Journal: Chemical & Biomedical Imaging
Article Title: Natural Selection-Guided ACE2-Targeted Molecular Imaging: A New Paradigm for PET Tracer Development
doi: 10.1021/cbmi.5c00053
Figure Lengend Snippet: Biosafety and chemical stability. (A) The cytotoxicity characterized by the cell division rate that was determined using the CFDA SE staining of HEK293-hACE2 cells treated with Omi-X. (B) The cell cycle analysis of HEK293-hACE2 cells treated with different concentrations of Omi-X. The percentage of cells in different phases was presented as bar graphs. (C) HPLC spectrum of chemical stability of Omi-X.
Article Snippet: The cell-division rate was assessed using Carboxyfluorescein diacetate, succinimidyl ester (CFDA SE) Cell Proliferation Assay and Tracking Kit (Beyotime Biotechnology) according to the manufacturer’s protocol.
Techniques: Staining, Cell Cycle Assay