Review



bxpc 3  (ATCC)


Bioz Verified Symbol ATCC is a verified supplier
Bioz Manufacturer Symbol ATCC manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 99
      Buy from Supplier

    Structured Review

    ATCC bxpc 3
    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, <t>BxPC-3,</t> PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.
    Bxpc 3, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 5080 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bxpc 3/product/ATCC
    Average 99 stars, based on 5080 article reviews
    bxpc 3 - by Bioz Stars, 2026-03
    99/100 stars

    Images

    1) Product Images from "Ubiquitination of Oncogenic Mutant p53 via Attenuation of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth"

    Article Title: Ubiquitination of Oncogenic Mutant p53 via Attenuation of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth

    Journal: Molecular Cancer Therapeutics

    doi: 10.1158/1535-7163.MCT-25-0097

    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, BxPC-3, PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.
    Figure Legend Snippet: BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, BxPC-3, PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.

    Techniques Used: MTT Assay, Stripping Membranes, Control, Labeling



    Similar Products

    bxpc 3  (ATCC)
    99
    ATCC bxpc 3
    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, <t>BxPC-3,</t> PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.
    Bxpc 3, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bxpc 3/product/ATCC
    Average 99 stars, based on 1 article reviews
    bxpc 3 - by Bioz Stars, 2026-03
    99/100 stars
    		  Buy from Supplier
    bxpc3  (ATCC)
    99
    ATCC bxpc3
    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, <t>BxPC-3,</t> PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.
    Bxpc3, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bxpc3/product/ATCC
    Average 99 stars, based on 1 article reviews
    bxpc3 - by Bioz Stars, 2026-03
    99/100 stars
    		  Buy from Supplier
    bxpc 3 cells  (ATCC)
    99
    ATCC bxpc 3 cells
    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, <t>BxPC-3,</t> PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.
    Bxpc 3 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bxpc 3 cells/product/ATCC
    Average 99 stars, based on 1 article reviews
    bxpc 3 cells - by Bioz Stars, 2026-03
    99/100 stars
    		  Buy from Supplier
    bxpc3 cells  (ATCC)
    99
    ATCC bxpc3 cells
    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, <t>BxPC-3,</t> PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.
    Bxpc3 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bxpc3 cells/product/ATCC
    Average 99 stars, based on 1 article reviews
    bxpc3 cells - by Bioz Stars, 2026-03
    99/100 stars
    		  Buy from Supplier
    1687 lncap atcc cat  (ATCC)
    99
    ATCC 1687 lncap atcc cat
    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, <t>BxPC-3,</t> PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.
    1687 Lncap Atcc Cat, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/1687 lncap atcc cat/product/ATCC
    Average 99 stars, based on 1 article reviews
    1687 lncap atcc cat - by Bioz Stars, 2026-03
    99/100 stars
    		  Buy from Supplier

    Image Search Results


    BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, BxPC-3, PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.

    Journal: Molecular Cancer Therapeutics

    Article Title: Ubiquitination of Oncogenic Mutant p53 via Attenuation of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth

    doi: 10.1158/1535-7163.MCT-25-0097

    Figure Lengend Snippet: BMH-21 preferentially inhibits cell viability and induces apoptosis in pancreatic cancer cells. A, Effect of BMH-21 on cell viability of HPDEC and pancreatic cancer cells (Capan-2, AsPC-1, BxPC-3, PANC-1, HPAF-II, and MIA PaCa-2). Cells were treated with indicated concentrations of BMH-21 for 24 hours, and cell viability was analyzed via MTT assay. B–E, Effect of BMH-21 on apoptosis induction in HPDEC and pancreatic cancer cells. B, Effect of BMH-21 on PARP in HPDEC and pancreatic cancer cells as assessed using WB. Briefly, cells were treated with indicated concentrations of BMH-21 for 12 hours. Total PARP and cleaved PARP (cl-PARP) were detected by WB analysis. Equal loading of protein was determined by stripping and probing the blots with β-actin antibody. C and D, Flow cytometric analysis to detect apoptotic cells in control and BMH-21 (2 μmol/L)–treated HPDEC and MIA PaCa-2 cells using Alexa Fluor 488–labeled Annexin V. Representative flow cytometric images showing percent Alexa Fluor 488–tagged Annexin V–positive cells. E, The bar graph represents the percentage of live and apoptotic HPDEC and MIA PaCa-2 cells after BMH-21 treatment. The data represent the mean ± SEM of three samples. The P values were expressed as follows: **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001. PI, propidium iodide.

    Article Snippet: Capan-2, AsPC-1, MIA PaCa-2, HPAF-II, BxPC-3, PANC-1, and HPNE were obtained from ATCC.

    Techniques: MTT Assay, Stripping Membranes, Control, Labeling