Review



v2r  (Bioss)


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    Structured Review

    Bioss v2r
    ZWD inhibits renal MR and <t>V2R</t> expression in NS. (A) Protein levels of MR and V2R detected by WB ( n = 6). (B–C) mRNA levels of MR and V2R detected by RT-qPCR ( n = 6). Model group vs. control group (** p < 0.01, ANOVA followed by LSD); ZWD and prednisone groups vs. model group (# p < 0.05, ## p < 0.01, ANOVA followed by LSD). V2R: type 2 <t>vasopressin</t> <t>receptor;</t> MR: mineralocorticoid receptor; ZWD: Zhenwu Decoction; LSD: least significant difference; WB: western blot.
    V2r, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/v2r/product/Bioss
    Average 94 stars, based on 2 article reviews
    v2r - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "Zhenwu decoction ameliorates adriamycin-induced nephrotic syndrome in rats via dual modulation of AVP-V2R-AQP2 and RAAS-MR-AQP3 pathways"

    Article Title: Zhenwu decoction ameliorates adriamycin-induced nephrotic syndrome in rats via dual modulation of AVP-V2R-AQP2 and RAAS-MR-AQP3 pathways

    Journal: Renal Failure

    doi: 10.1080/0886022X.2025.2599570

    ZWD inhibits renal MR and V2R expression in NS. (A) Protein levels of MR and V2R detected by WB ( n = 6). (B–C) mRNA levels of MR and V2R detected by RT-qPCR ( n = 6). Model group vs. control group (** p < 0.01, ANOVA followed by LSD); ZWD and prednisone groups vs. model group (# p < 0.05, ## p < 0.01, ANOVA followed by LSD). V2R: type 2 vasopressin receptor; MR: mineralocorticoid receptor; ZWD: Zhenwu Decoction; LSD: least significant difference; WB: western blot.
    Figure Legend Snippet: ZWD inhibits renal MR and V2R expression in NS. (A) Protein levels of MR and V2R detected by WB ( n = 6). (B–C) mRNA levels of MR and V2R detected by RT-qPCR ( n = 6). Model group vs. control group (** p < 0.01, ANOVA followed by LSD); ZWD and prednisone groups vs. model group (# p < 0.05, ## p < 0.01, ANOVA followed by LSD). V2R: type 2 vasopressin receptor; MR: mineralocorticoid receptor; ZWD: Zhenwu Decoction; LSD: least significant difference; WB: western blot.

    Techniques Used: Expressing, Quantitative RT-PCR, Control, Western Blot

    Compound–major target molecular docking analysis. (A) Initial 3D conformation of unoptimized bioactive compounds. (B) 3D conformation of optimized bioactive compounds. (C) Interaction mode of AQP1 with benzoylpaeoniflorin. (D–F) Interaction mode of AQP2, V2R, and MR with 6-gingerol. (G) Interaction mode of AQP3 with paeoniflorin. AQP: aquaporin; V2R: type 2 vasopressin receptor; MR: mineralocorticoid receptor.
    Figure Legend Snippet: Compound–major target molecular docking analysis. (A) Initial 3D conformation of unoptimized bioactive compounds. (B) 3D conformation of optimized bioactive compounds. (C) Interaction mode of AQP1 with benzoylpaeoniflorin. (D–F) Interaction mode of AQP2, V2R, and MR with 6-gingerol. (G) Interaction mode of AQP3 with paeoniflorin. AQP: aquaporin; V2R: type 2 vasopressin receptor; MR: mineralocorticoid receptor.

    Techniques Used:



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