Journal: Frontiers in Immunology
Article Title: Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a bronchoscopy endobronchial biopsy study
doi: 10.3389/fimmu.2025.1531279
Figure Lengend Snippet: Relative expression changes of N-cadherin and E-cadherin in human-derived lung primary epithelial cells (HC and ACO patients) post induction with Th-2 cytokine IL-13, CSE and EMT activator TGF-β. # p<0.05, *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.
Article Snippet: Cigarette smoke extract (CSE) was prepared by bubbling smoke from one filter-less Kentucky research cigarette, 3R4F, which contains 9.5 mg of tar and 0.8 mg of nicotine, through 10 mL of Bronchial Epithelial Basal Medium (BEBM, Lonza) at a rate of one cigarette every 5 minutes ( ).
Techniques: Expressing, Derivative Assay