Review



bay876  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 95
      Buy from Supplier

    Structured Review

    MedChemExpress bay876
    Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + <t>BAY876</t> (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.
    Bay876, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 63 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bay876/product/MedChemExpress
    Average 95 stars, based on 63 article reviews
    bay876 - by Bioz Stars, 2026-02
    95/100 stars

    Images

    1) Product Images from "Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis ☆ "

    Article Title: Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis ☆

    Journal: The World Allergy Organization Journal

    doi: 10.1016/j.waojou.2025.101158

    Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + BAY876 (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.
    Figure Legend Snippet: Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + BAY876 (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.

    Techniques Used: Marker, Expressing, Immunofluorescence, Staining, Western Blot

    GLUT1 inhibitor alleviates allergen-mediated nasal mucosal inflammation and barrier function damage in murine AR model. (A) Representative HE and immunofluorescence images of nasal mucosal in PBS, AR and AR + BAY876 groups (n = 5); (B) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (C) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (D) IL-4, IL-13, IL-17A and IFN-γ concentrations in nasal lavage fluid (n = 5). AR, allergic rhinitis; GLUT1, glucose transporter 1; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.
    Figure Legend Snippet: GLUT1 inhibitor alleviates allergen-mediated nasal mucosal inflammation and barrier function damage in murine AR model. (A) Representative HE and immunofluorescence images of nasal mucosal in PBS, AR and AR + BAY876 groups (n = 5); (B) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (C) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (D) IL-4, IL-13, IL-17A and IFN-γ concentrations in nasal lavage fluid (n = 5). AR, allergic rhinitis; GLUT1, glucose transporter 1; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.

    Techniques Used: Immunofluorescence, Fluorescence



    Similar Products

    bay876  (MedChemExpress)
    95
    MedChemExpress bay876
    Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + <t>BAY876</t> (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.
    Bay876, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bay876/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    bay876 - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    glut1 inhibitor bay876  (MedChemExpress)
    95
    MedChemExpress glut1 inhibitor bay876
    Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + <t>BAY876</t> (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.
    Glut1 Inhibitor Bay876, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/glut1 inhibitor bay876/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    glut1 inhibitor bay876 - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    bay876  (Millipore)
    90
    Millipore bay876
    Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + <t>BAY876</t> (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.
    Bay876, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bay876/product/Millipore
    Average 90 stars, based on 1 article reviews
    bay876 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + BAY876 (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.

    Journal: The World Allergy Organization Journal

    Article Title: Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis ☆

    doi: 10.1016/j.waojou.2025.101158

    Figure Lengend Snippet: Inhibiting GLUT1 alleviates the suppression of tight junction marker expression in nasal epithelial cells mediated by HDM. (A–B) Cell immunofluorescence staining for GLUT1, ZO-1 and occluding in nasal epithelial cells treated with PBS, HDM and HDM + BAY876 (n = 6); WB showing GLUT1, ZO-1 and occluding protein expression in nasal epithelial cells among the 3 groups (n = 6). HDM, house dust mite; GLUT1, glucose transporter 1; WB, western blotting. ∗P < 0.05, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.

    Article Snippet: To investigate the effects of inhibiting GLUT1 on cellular function, cells were pretreated with 50 nM BAY876 (MedChemExpress, Monmouth Junction, USA) for 6 h before exposure to 20 μg/mL HDM, followed by a combined intervention for 48 h.

    Techniques: Marker, Expressing, Immunofluorescence, Staining, Western Blot

    GLUT1 inhibitor alleviates allergen-mediated nasal mucosal inflammation and barrier function damage in murine AR model. (A) Representative HE and immunofluorescence images of nasal mucosal in PBS, AR and AR + BAY876 groups (n = 5); (B) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (C) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (D) IL-4, IL-13, IL-17A and IFN-γ concentrations in nasal lavage fluid (n = 5). AR, allergic rhinitis; GLUT1, glucose transporter 1; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.

    Journal: The World Allergy Organization Journal

    Article Title: Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis ☆

    doi: 10.1016/j.waojou.2025.101158

    Figure Lengend Snippet: GLUT1 inhibitor alleviates allergen-mediated nasal mucosal inflammation and barrier function damage in murine AR model. (A) Representative HE and immunofluorescence images of nasal mucosal in PBS, AR and AR + BAY876 groups (n = 5); (B) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (C) Relative fluorescence intensity of GLUT1, ZO-1 and occluding among the 3 groups (n = 5); (D) IL-4, IL-13, IL-17A and IFN-γ concentrations in nasal lavage fluid (n = 5). AR, allergic rhinitis; GLUT1, glucose transporter 1; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.

    Article Snippet: To investigate the effects of inhibiting GLUT1 on cellular function, cells were pretreated with 50 nM BAY876 (MedChemExpress, Monmouth Junction, USA) for 6 h before exposure to 20 μg/mL HDM, followed by a combined intervention for 48 h.

    Techniques: Immunofluorescence, Fluorescence