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artesunate  (MedChemExpress)


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    Structured Review

    MedChemExpress artesunate
    Artesunate, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 42 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/artesunate/Artesunate/custom%40hy-n0193%4042390957
    Average 95 stars, based on 42 article reviews
    artesunate - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    other:

    Article Title: Artesunate ameliorates experimental autoimmune uveitis by inhibiting the LCN2-STAT3 axis and suppressing microglial activation
    Article Snippet: Artesunate (MedChemExpress, HY-N0193) was initially dissolved in DMSO and further diluted with PBS to yield a 4 mg/mL solution.

    Injection:

    Article Title: Artesunate ameliorates experimental autoimmune uveitis by inhibiting the LCN2-STAT3 axis and suppressing microglial activation.
    Article Snippet: .. Artesunate (MedChemExpress, HY-N0193) was serially diluted in running buffer to six concentrations (0–500 μM) and injected over all flow cells at 30 μL/min using a multi-cycle kinetics method (120 s association, 200 s dissociation). ..

    Article Title: Artesunate ameliorates experimental autoimmune uveitis by inhibiting the LCN2-STAT3 axis and suppressing microglial activation
    Article Snippet: .. Artesunate (MedChemExpress, HY-N0193) was serially diluted in running buffer to six concentrations (0–500 μM) and injected over all flow cells at 30 μL/min using a multi-cycle kinetics method (120 s association, 200 s dissociation). ..



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    Prediction-corrected visual predictive checks (pcVPCs) for the final pharmacokinetic models of ( a ) mefloquine and ( b ) <t>artesunate.</t> Closed circles represent the prediction-corrected observed plasma concentrations. The black dashed lines indicate the median and 90% prediction interval (PI) of the observed data, overlaid on the model-simulated prediction intervals.
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    Shanghai Yuanye Biochemicals artesunate
    <t>Artesunate</t> (ART) alleviates APAP‐induced liver injury. (A) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 400 mg/kg APAP, and 1 h later, they were injected with ART. The samples were collected 24 h later (n = 8). (B,C) The levels of ALT and AST in the serum of the mice (n = 8). (D–F) The levels of TNF‐α, IL‐6, and IL‐1β in the serum of the mice (n = 8). (G) LDH levels in the serum of the mice (n = 8). (H) Representative images of H&E and TUNEL staining of the livers of the mice. (I) Quantification of necrotic area in the livers of the mice (n = 8). (J) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 400 mg/kg APAP, and 10 h later, they were injected with ART. The samples were collected 24 h later (n = 8). (K,L) The levels of ALT and AST in the serum of the mice (n = 8). (M) Representative images of HE‐stained livers from the mice. (N) Quantification of the necrotic area in the livers of the mice (n = 8). (O) LDH levels in the serum of the mice (n = 8). (P) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 650 mg/kg APAP, and 10 h later, they were injected with ART (n = 10). (Q) Survival curve of mice treated with ART after the administration of a lethal dose of APAP (n = 10). Data are presented as mean ± SEM. ** P < 0.01.
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    Image Search Results


    Prediction-corrected visual predictive checks (pcVPCs) for the final pharmacokinetic models of ( a ) mefloquine and ( b ) artesunate. Closed circles represent the prediction-corrected observed plasma concentrations. The black dashed lines indicate the median and 90% prediction interval (PI) of the observed data, overlaid on the model-simulated prediction intervals.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Pharmacokinetic and pharmacodynamic modeling of anti-plasmodial drugs mefloquine plus artesunate: insights on translational application

    doi: 10.1128/aac.01717-25

    Figure Lengend Snippet: Prediction-corrected visual predictive checks (pcVPCs) for the final pharmacokinetic models of ( a ) mefloquine and ( b ) artesunate. Closed circles represent the prediction-corrected observed plasma concentrations. The black dashed lines indicate the median and 90% prediction interval (PI) of the observed data, overlaid on the model-simulated prediction intervals.

    Article Snippet: Mefloquine hydrochloride (MQ) was purchased from Sigma-Aldrich, and Artesunate was purchased from TCI Chemicals.

    Techniques: Clinical Proteomics

    Simulated effect of mefloquine (left panel) and artesunate (right panel) on parasitemia reduction following a single dose of ASMQ combination therapy in mice. The black line represents the median predicted response, and the shaded area indicates the 5th to 95th percentile prediction interval.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Pharmacokinetic and pharmacodynamic modeling of anti-plasmodial drugs mefloquine plus artesunate: insights on translational application

    doi: 10.1128/aac.01717-25

    Figure Lengend Snippet: Simulated effect of mefloquine (left panel) and artesunate (right panel) on parasitemia reduction following a single dose of ASMQ combination therapy in mice. The black line represents the median predicted response, and the shaded area indicates the 5th to 95th percentile prediction interval.

    Article Snippet: Mefloquine hydrochloride (MQ) was purchased from Sigma-Aldrich, and Artesunate was purchased from TCI Chemicals.

    Techniques:

    Simulated parasitemia percentage profiles generated using “true” pharmacokinetic parameters of mefloquine + artesunate ( a ) and artesuane alone ( b ). A total of 1,000 simulations were performed; the black line represents the median prediction, and the shaded area indicates the 5th to 95th percentile prediction interval.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Pharmacokinetic and pharmacodynamic modeling of anti-plasmodial drugs mefloquine plus artesunate: insights on translational application

    doi: 10.1128/aac.01717-25

    Figure Lengend Snippet: Simulated parasitemia percentage profiles generated using “true” pharmacokinetic parameters of mefloquine + artesunate ( a ) and artesuane alone ( b ). A total of 1,000 simulations were performed; the black line represents the median prediction, and the shaded area indicates the 5th to 95th percentile prediction interval.

    Article Snippet: Mefloquine hydrochloride (MQ) was purchased from Sigma-Aldrich, and Artesunate was purchased from TCI Chemicals.

    Techniques: Generated

    Artesunate (ART) alleviates APAP‐induced liver injury. (A) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 400 mg/kg APAP, and 1 h later, they were injected with ART. The samples were collected 24 h later (n = 8). (B,C) The levels of ALT and AST in the serum of the mice (n = 8). (D–F) The levels of TNF‐α, IL‐6, and IL‐1β in the serum of the mice (n = 8). (G) LDH levels in the serum of the mice (n = 8). (H) Representative images of H&E and TUNEL staining of the livers of the mice. (I) Quantification of necrotic area in the livers of the mice (n = 8). (J) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 400 mg/kg APAP, and 10 h later, they were injected with ART. The samples were collected 24 h later (n = 8). (K,L) The levels of ALT and AST in the serum of the mice (n = 8). (M) Representative images of HE‐stained livers from the mice. (N) Quantification of the necrotic area in the livers of the mice (n = 8). (O) LDH levels in the serum of the mice (n = 8). (P) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 650 mg/kg APAP, and 10 h later, they were injected with ART (n = 10). (Q) Survival curve of mice treated with ART after the administration of a lethal dose of APAP (n = 10). Data are presented as mean ± SEM. ** P < 0.01.

    Journal: Advanced Science

    Article Title: Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

    doi: 10.1002/advs.202521818

    Figure Lengend Snippet: Artesunate (ART) alleviates APAP‐induced liver injury. (A) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 400 mg/kg APAP, and 1 h later, they were injected with ART. The samples were collected 24 h later (n = 8). (B,C) The levels of ALT and AST in the serum of the mice (n = 8). (D–F) The levels of TNF‐α, IL‐6, and IL‐1β in the serum of the mice (n = 8). (G) LDH levels in the serum of the mice (n = 8). (H) Representative images of H&E and TUNEL staining of the livers of the mice. (I) Quantification of necrotic area in the livers of the mice (n = 8). (J) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 400 mg/kg APAP, and 10 h later, they were injected with ART. The samples were collected 24 h later (n = 8). (K,L) The levels of ALT and AST in the serum of the mice (n = 8). (M) Representative images of HE‐stained livers from the mice. (N) Quantification of the necrotic area in the livers of the mice (n = 8). (O) LDH levels in the serum of the mice (n = 8). (P) Schematic diagram of the experimental procedure. The mice were fasted for 16 h, then intraperitoneally injected with 650 mg/kg APAP, and 10 h later, they were injected with ART (n = 10). (Q) Survival curve of mice treated with ART after the administration of a lethal dose of APAP (n = 10). Data are presented as mean ± SEM. ** P < 0.01.

    Article Snippet: Artesunate (S24000;98%/ B20992 ) and Acetaminophen ( S31044 ;99%, AR/ B20338 ) were purchased from Shanghai Yuanye Bio‐Technology Co., Ltd. (Shanghai, China).

    Techniques: Injection, TUNEL Assay, Staining