Journal: Poultry Science
Article Title: A Novel PLGA-based nano-adjuvant augments mucosal and systemic immunity in chicks through intestinal targeting and IgA production
doi: 10.1016/j.psj.2026.106641
Figure Lengend Snippet: (A) Transmission electron microscopy (TEM) image of PEI-LSP-RA-PLGA, (B) Scanning electron microscopy (SEM) image of freeze-dried PEI-LSP-RA-PLGA, (C) Stability photographs, (D) Particle size change graph, (E) Zeta potential and PDI variation graph, (F) Loading efficiency of LSP, RA, and H9N2 in PEI-LSP-RA-PLGA, (G) In vitro release profile of H9N2.
Article Snippet: The H9N2 antigen (Luoyang Pulike, China) was mixed with the adjuvants PEI-LSP-RA-PLGA, PEI-RA-PLGA, LSP, and Alum (Thermo, USA) at a volume ratio of 1:3 and shaken on a shaker for 30 minutes to prepare PEI-LSP-RA-PLGA/H9N2, PEI-LSP-PLGA/H9N2, LSP/H9N2, and Alum/H9N2.
Techniques: Transmission Assay, Electron Microscopy, Zeta Potential Analyzer, In Vitro