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ana12  (MedChemExpress)


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    Structured Review

    MedChemExpress ana12
    Ana12, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 60 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ana12/ANA-12/bio_rxiv__64898__2026__03__12__711120-180-8-23
    Average 95 stars, based on 60 article reviews
    ana12 - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    other:

    Article Title: Differential contribution of TrkB and p75 NTR to BDNF-dependent self-renewal, proliferation, and differentiation of adult neural stem cells.
    Article Snippet: When indicated, NSC cultures were treated with 10μM ANA12 (MedChemExpress; Cat #HY-12497) (hereafter referred to as TrkB-i) or 10μM THX-B (MedChemExpress; Cat #HY-137322) (hereafter referred to as p75-i) at the time of plating to inhibit TrkB or p75NTR, respectively.

    Article Title: Fibroblasts neurotrophin signaling sustains pathological vascular maturation in rheumatoid arthritis
    Article Snippet: Small-molecule inhibitors, including GW-441756 (#2238, Tocris, TrkA inhibitor), ANA12 (#4781, Tocris, TrkB inhibitor), GNF 5837 (#4559, Tocris TrkA/BC inhibitor), Entrectinib (Cat. No.: HY-12678, MedChemExpress) Larotrectinib (Cat. No.: HY-12866, MedChemExpress) were used at concentrations of 1, 5, and 10 μM respectively.

    Article Title: Xiaochaihutang ameliorates depression-like behaviors induced via chronic social defeat stress by regulating exon-specific Bdnf transcription through H3K18 acetylation in the hippocampus of mice.
    Article Snippet: Introduction: Depression is a prevalent and persistent mental disease characterized by symptoms such as anhedonia, anxiety, and desperation.. Although our previous study shows that Xiaochaihutang (XCHT) upregulates hippocampal brain-derived neurotrophic factor (BDNF) levels in depressed mice and rats, the underlying mechanism requires further clarification.. Objectives: To assess the mechanism by which XCHT regulates hippocampal BDNF expression in chronic social defeat stress (CSDS)-induced mice.

    Article Title: Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway
    Article Snippet: ANA12, TrkB antagonist, was purchased from MedChemExpres (MCE, Catalog HY-12497, USA).

    Saline:

    Article Title: The causal involvement of the BDNF-TrkB pathway in dentate gyrus in early-life stress-induced cognitive deficits
    Article Snippet: .. Drug administration For intraperitoneal administration (i.p.), 7,8-dihydroxy avone (7,8-DHF; Catalog number: D5446, SigmaAldrich, United States, 5 mg/kg) was prepared in vehicle of 20% β-cyclodextrin in normal saline, and ANA12 (Catalog number: HY-12497, MedChem Express, USA, 0.5 mg/kg) was prepared in vehicle of 20% βcyclodextrin in normal saline. ..



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