Review



amk  (TargetMol)


Bioz Verified Symbol TargetMol is a verified supplier
Bioz Manufacturer Symbol TargetMol manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    TargetMol amk
    Amk, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/amk/product/TargetMol
    Average 93 stars, based on 1 article reviews
    amk - by Bioz Stars, 2026-05
    93/100 stars

    Images



    Similar Products

    biofilm amr mechanisms s aureus atcc 25923 van oxa cip rif gen tob stp kan amk hurdle  (ATCC)
    99
    ATCC biofilm amr mechanisms s aureus atcc 25923 van oxa cip rif gen tob stp kan amk hurdle
    Biofilm Amr Mechanisms S Aureus Atcc 25923 Van Oxa Cip Rif Gen Tob Stp Kan Amk Hurdle, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/biofilm amr mechanisms s aureus atcc 25923 van oxa cip rif gen tob stp kan amk hurdle/product/ATCC
    Average 99 stars, based on 1 article reviews
    biofilm amr mechanisms s aureus atcc 25923 van oxa cip rif gen tob stp kan amk hurdle - by Bioz Stars, 2026-05
    99/100 stars
    		  Buy from Supplier
    a7699 amikacin disulfate salt amk acros organics 455190050 au1235 medchemexpress hy 101867 az7371 cayman chemical 19310 bedaquiline bdq  (MedChemExpress)
    94
    MedChemExpress a7699 amikacin disulfate salt amk acros organics 455190050 au1235 medchemexpress hy 101867 az7371 cayman chemical 19310 bedaquiline bdq
    A7699 Amikacin Disulfate Salt Amk Acros Organics 455190050 Au1235 Medchemexpress Hy 101867 Az7371 Cayman Chemical 19310 Bedaquiline Bdq, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/a7699 amikacin disulfate salt amk acros organics 455190050 au1235 medchemexpress hy 101867 az7371 cayman chemical 19310 bedaquiline bdq/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    a7699 amikacin disulfate salt amk acros organics 455190050 au1235 medchemexpress hy 101867 az7371 cayman chemical 19310 bedaquiline bdq - by Bioz Stars, 2026-05
    94/100 stars
    		  Buy from Supplier
    amikacin amk  (Shanghai Yuanye Biochemicals)
    86
    Shanghai Yuanye Biochemicals amikacin amk
    Amikacin Amk, supplied by Shanghai Yuanye Biochemicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/amikacin amk/product/Shanghai Yuanye Biochemicals
    Average 86 stars, based on 1 article reviews
    amikacin amk - by Bioz Stars, 2026-05
    86/100 stars
    		  Buy from Supplier
    amk  (TargetMol)
    93
    TargetMol amk
    Amk, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/amk/product/TargetMol
    Average 93 stars, based on 1 article reviews
    amk - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    amikacin amk  (MedChemExpress)
    92
    MedChemExpress amikacin amk
    Amikacin Amk, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/amikacin amk/product/MedChemExpress
    Average 92 stars, based on 1 article reviews
    amikacin amk - by Bioz Stars, 2026-05
    92/100 stars
    		  Buy from Supplier
    amikacin amk  (Sangon Biotech)
    86
    Sangon Biotech amikacin amk
    IleRS-silenced (IleRS_KD) strains were compared with empty vector strains (PLJR962_KD) under four treatment conditions: untreated, PZA without ATC (no IleRS silencing), ATC alone (silencing control), and ATC + PZA. A Bar charts demonstrates the synergistic bactericidal effect of IleRS silencing and PZA on M. abscessus and M. marinum under acidic conditions (pH 5.0 and 5.5), with greater killing when ATC + PZA are combined than with either treatment alone ( n = 3). B In the NR medium (non-replicating stress model; see Methods), IleRS silencing further enhances PZA activity, indicating a synergistic interaction under stress ( n = 3). C alamarBlue microplate assay determining minimum inhibitory concentrations (MICs) of isoniazid (INH), rifampicin (RFP), ethambutol (EMB), pyrazinamide (PZA), <t>amikacin</t> <t>(AMK),</t> moxifloxacin (MXF), ethionamide (ETH), D-cycloserine (DCS), sodium para-aminosalicylic acid (PAS), linezolid (LZD), bedaquiline (BDQ), meropenem (MEM), clofazimine (CFZ), and clarithromycin (CLA). Drugs were tested at 0.004×–0.5× MIC. Empty vector strains and IleRS-silenced strains were tested with or without ATC induction. D Survival of M. abscessus and M. marinum in RAW 264.7 and THP-1 macrophage infected at MOI = 1. At 24 and 72 h post-infection, macrophages were washed, extracellular bacteria were removed with gentamicin (see Methods), cells were lysed with 0.01% SDS, and lysates were plated on 7H10 to quantify viable bacteria ( n = 3). Error bars represent mean ± SD. Statistical significance was determined by two-way ANOVA. Differences were considered statistically significant at P < 0.05 (*), P < 0.01 (**), P < 0.001 (***), and P < 0.0001 (****). “ns” denotes no significant difference.
    Amikacin Amk, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/amikacin amk/product/Sangon Biotech
    Average 86 stars, based on 1 article reviews
    amikacin amk - by Bioz Stars, 2026-05
    86/100 stars
    		  Buy from Supplier
    amk  (Santa Cruz Biotechnology)
    93
    Santa Cruz Biotechnology amk
    IleRS-silenced (IleRS_KD) strains were compared with empty vector strains (PLJR962_KD) under four treatment conditions: untreated, PZA without ATC (no IleRS silencing), ATC alone (silencing control), and ATC + PZA. A Bar charts demonstrates the synergistic bactericidal effect of IleRS silencing and PZA on M. abscessus and M. marinum under acidic conditions (pH 5.0 and 5.5), with greater killing when ATC + PZA are combined than with either treatment alone ( n = 3). B In the NR medium (non-replicating stress model; see Methods), IleRS silencing further enhances PZA activity, indicating a synergistic interaction under stress ( n = 3). C alamarBlue microplate assay determining minimum inhibitory concentrations (MICs) of isoniazid (INH), rifampicin (RFP), ethambutol (EMB), pyrazinamide (PZA), <t>amikacin</t> <t>(AMK),</t> moxifloxacin (MXF), ethionamide (ETH), D-cycloserine (DCS), sodium para-aminosalicylic acid (PAS), linezolid (LZD), bedaquiline (BDQ), meropenem (MEM), clofazimine (CFZ), and clarithromycin (CLA). Drugs were tested at 0.004×–0.5× MIC. Empty vector strains and IleRS-silenced strains were tested with or without ATC induction. D Survival of M. abscessus and M. marinum in RAW 264.7 and THP-1 macrophage infected at MOI = 1. At 24 and 72 h post-infection, macrophages were washed, extracellular bacteria were removed with gentamicin (see Methods), cells were lysed with 0.01% SDS, and lysates were plated on 7H10 to quantify viable bacteria ( n = 3). Error bars represent mean ± SD. Statistical significance was determined by two-way ANOVA. Differences were considered statistically significant at P < 0.05 (*), P < 0.01 (**), P < 0.001 (***), and P < 0.0001 (****). “ns” denotes no significant difference.
    Amk, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/amk/product/Santa Cruz Biotechnology
    Average 93 stars, based on 1 article reviews
    amk - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    reference strain subspecies clrb amk ipm fox mxf rfb lzd cfz tgc bdq atcc 19977 abscessus  (ATCC)
    99
    ATCC reference strain subspecies clrb amk ipm fox mxf rfb lzd cfz tgc bdq atcc 19977 abscessus
    IleRS-silenced (IleRS_KD) strains were compared with empty vector strains (PLJR962_KD) under four treatment conditions: untreated, PZA without ATC (no IleRS silencing), ATC alone (silencing control), and ATC + PZA. A Bar charts demonstrates the synergistic bactericidal effect of IleRS silencing and PZA on M. abscessus and M. marinum under acidic conditions (pH 5.0 and 5.5), with greater killing when ATC + PZA are combined than with either treatment alone ( n = 3). B In the NR medium (non-replicating stress model; see Methods), IleRS silencing further enhances PZA activity, indicating a synergistic interaction under stress ( n = 3). C alamarBlue microplate assay determining minimum inhibitory concentrations (MICs) of isoniazid (INH), rifampicin (RFP), ethambutol (EMB), pyrazinamide (PZA), <t>amikacin</t> <t>(AMK),</t> moxifloxacin (MXF), ethionamide (ETH), D-cycloserine (DCS), sodium para-aminosalicylic acid (PAS), linezolid (LZD), bedaquiline (BDQ), meropenem (MEM), clofazimine (CFZ), and clarithromycin (CLA). Drugs were tested at 0.004×–0.5× MIC. Empty vector strains and IleRS-silenced strains were tested with or without ATC induction. D Survival of M. abscessus and M. marinum in RAW 264.7 and THP-1 macrophage infected at MOI = 1. At 24 and 72 h post-infection, macrophages were washed, extracellular bacteria were removed with gentamicin (see Methods), cells were lysed with 0.01% SDS, and lysates were plated on 7H10 to quantify viable bacteria ( n = 3). Error bars represent mean ± SD. Statistical significance was determined by two-way ANOVA. Differences were considered statistically significant at P < 0.05 (*), P < 0.01 (**), P < 0.001 (***), and P < 0.0001 (****). “ns” denotes no significant difference.
    Reference Strain Subspecies Clrb Amk Ipm Fox Mxf Rfb Lzd Cfz Tgc Bdq Atcc 19977 Abscessus, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/reference strain subspecies clrb amk ipm fox mxf rfb lzd cfz tgc bdq atcc 19977 abscessus/product/ATCC
    Average 99 stars, based on 1 article reviews
    reference strain subspecies clrb amk ipm fox mxf rfb lzd cfz tgc bdq atcc 19977 abscessus - by Bioz Stars, 2026-05
    99/100 stars
    		  Buy from Supplier
    amikacin amk  (Euromedex)
    90
    Euromedex amikacin amk
    IleRS-silenced (IleRS_KD) strains were compared with empty vector strains (PLJR962_KD) under four treatment conditions: untreated, PZA without ATC (no IleRS silencing), ATC alone (silencing control), and ATC + PZA. A Bar charts demonstrates the synergistic bactericidal effect of IleRS silencing and PZA on M. abscessus and M. marinum under acidic conditions (pH 5.0 and 5.5), with greater killing when ATC + PZA are combined than with either treatment alone ( n = 3). B In the NR medium (non-replicating stress model; see Methods), IleRS silencing further enhances PZA activity, indicating a synergistic interaction under stress ( n = 3). C alamarBlue microplate assay determining minimum inhibitory concentrations (MICs) of isoniazid (INH), rifampicin (RFP), ethambutol (EMB), pyrazinamide (PZA), <t>amikacin</t> <t>(AMK),</t> moxifloxacin (MXF), ethionamide (ETH), D-cycloserine (DCS), sodium para-aminosalicylic acid (PAS), linezolid (LZD), bedaquiline (BDQ), meropenem (MEM), clofazimine (CFZ), and clarithromycin (CLA). Drugs were tested at 0.004×–0.5× MIC. Empty vector strains and IleRS-silenced strains were tested with or without ATC induction. D Survival of M. abscessus and M. marinum in RAW 264.7 and THP-1 macrophage infected at MOI = 1. At 24 and 72 h post-infection, macrophages were washed, extracellular bacteria were removed with gentamicin (see Methods), cells were lysed with 0.01% SDS, and lysates were plated on 7H10 to quantify viable bacteria ( n = 3). Error bars represent mean ± SD. Statistical significance was determined by two-way ANOVA. Differences were considered statistically significant at P < 0.05 (*), P < 0.01 (**), P < 0.001 (***), and P < 0.0001 (****). “ns” denotes no significant difference.
    Amikacin Amk, supplied by Euromedex, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/amikacin amk/product/Euromedex
    Average 90 stars, based on 1 article reviews
    amikacin amk - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    IleRS-silenced (IleRS_KD) strains were compared with empty vector strains (PLJR962_KD) under four treatment conditions: untreated, PZA without ATC (no IleRS silencing), ATC alone (silencing control), and ATC + PZA. A Bar charts demonstrates the synergistic bactericidal effect of IleRS silencing and PZA on M. abscessus and M. marinum under acidic conditions (pH 5.0 and 5.5), with greater killing when ATC + PZA are combined than with either treatment alone ( n = 3). B In the NR medium (non-replicating stress model; see Methods), IleRS silencing further enhances PZA activity, indicating a synergistic interaction under stress ( n = 3). C alamarBlue microplate assay determining minimum inhibitory concentrations (MICs) of isoniazid (INH), rifampicin (RFP), ethambutol (EMB), pyrazinamide (PZA), amikacin (AMK), moxifloxacin (MXF), ethionamide (ETH), D-cycloserine (DCS), sodium para-aminosalicylic acid (PAS), linezolid (LZD), bedaquiline (BDQ), meropenem (MEM), clofazimine (CFZ), and clarithromycin (CLA). Drugs were tested at 0.004×–0.5× MIC. Empty vector strains and IleRS-silenced strains were tested with or without ATC induction. D Survival of M. abscessus and M. marinum in RAW 264.7 and THP-1 macrophage infected at MOI = 1. At 24 and 72 h post-infection, macrophages were washed, extracellular bacteria were removed with gentamicin (see Methods), cells were lysed with 0.01% SDS, and lysates were plated on 7H10 to quantify viable bacteria ( n = 3). Error bars represent mean ± SD. Statistical significance was determined by two-way ANOVA. Differences were considered statistically significant at P < 0.05 (*), P < 0.01 (**), P < 0.001 (***), and P < 0.0001 (****). “ns” denotes no significant difference.

    Journal: Communications Biology

    Article Title: Isoleucyl-tRNA synthetase depletion reveals vulnerabilities in Mycobacterium abscessus and Mycobacterium marinum

    doi: 10.1038/s42003-025-08841-y

    Figure Lengend Snippet: IleRS-silenced (IleRS_KD) strains were compared with empty vector strains (PLJR962_KD) under four treatment conditions: untreated, PZA without ATC (no IleRS silencing), ATC alone (silencing control), and ATC + PZA. A Bar charts demonstrates the synergistic bactericidal effect of IleRS silencing and PZA on M. abscessus and M. marinum under acidic conditions (pH 5.0 and 5.5), with greater killing when ATC + PZA are combined than with either treatment alone ( n = 3). B In the NR medium (non-replicating stress model; see Methods), IleRS silencing further enhances PZA activity, indicating a synergistic interaction under stress ( n = 3). C alamarBlue microplate assay determining minimum inhibitory concentrations (MICs) of isoniazid (INH), rifampicin (RFP), ethambutol (EMB), pyrazinamide (PZA), amikacin (AMK), moxifloxacin (MXF), ethionamide (ETH), D-cycloserine (DCS), sodium para-aminosalicylic acid (PAS), linezolid (LZD), bedaquiline (BDQ), meropenem (MEM), clofazimine (CFZ), and clarithromycin (CLA). Drugs were tested at 0.004×–0.5× MIC. Empty vector strains and IleRS-silenced strains were tested with or without ATC induction. D Survival of M. abscessus and M. marinum in RAW 264.7 and THP-1 macrophage infected at MOI = 1. At 24 and 72 h post-infection, macrophages were washed, extracellular bacteria were removed with gentamicin (see Methods), cells were lysed with 0.01% SDS, and lysates were plated on 7H10 to quantify viable bacteria ( n = 3). Error bars represent mean ± SD. Statistical significance was determined by two-way ANOVA. Differences were considered statistically significant at P < 0.05 (*), P < 0.01 (**), P < 0.001 (***), and P < 0.0001 (****). “ns” denotes no significant difference.

    Article Snippet: All antibiotics used in this study—including isoniazid (INH), rifampicin (RFP), ethambutol (EMB), pyrazinamide (PZA), amikacin (AMK), moxifloxacin (MXF), ethionamide (ETH), D-cycloserine (DCS), sodium para-aminosalicylic acid (PAS), linezolid (LZD), bedaquiline (BDQ), meropenem (MEM), clofazimine (CFZ), doxycycline (DOX) and clarithromycin (CLA)—were obtained from Sangon Biotech (Shanghai, China).

    Techniques: Plasmid Preparation, Control, Activity Assay, Infection, Bacteria