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thermosensitive liposomes (her2(+) affisomes  (Affibody)

 
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    Structured Review

    Affibody thermosensitive liposomes (her2(+) affisomes
    Thermosensitive Liposomes (Her2(+) Affisomes, supplied by Affibody, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/affisomes/anti+her2+affibody/pm40490771-1453-31-29
    Average 90 stars, based on 1 article reviews
    thermosensitive liposomes (her2(+) affisomes - by Bioz Stars, 2026-09
    90/100 stars

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    Article Title: HER2-Specific Affibody -Conjugated Thermosensitive Liposomes (Affisomes) for Improved Delivery of Anti-Cancer Agents
    Article Snippet: Both liposomes released calcein only at or above 40°C, confirming that affibody conjugation did not alter thermosensitivity of liposomes. fig ft0 fig mode=article f1 caption a4 caption a8 Effect of Affibody Conjugation on thermo-sensitivity of Liposomes For future medical applications, it is critical that physical properties of Affisomes are not altered upon storage or upon interactions with plasma components prior to targeting to permissive cells and/or tissues.

    Article Title: Affibody molecules for molecular imaging and targeted drug delivery in the management of breast cancer.
    Article Snippet: Breast cancer is one of the leading reasons for the morbidity and mortality of cancer related death globally.. The modern therapies are basically the combination of the breast-preserving surgeries or ablation with or without node biopsy or destroying the carcinoma cells adjuvant with chemotherapy, radiotherapy, hormonal or biological therapies depending upon the nature of the receptor of the cancerous cells, nature of the lymph node, as well as the tendency of the recurrence.. For decade’s carcinoma management suffered by the limitation of imagining, targeting and penetrability problem associated with management and cure of this deadly disease leads to unwanted chemo-toxicity and side effects.

    Article Title: HER2-Specific Affibody -Conjugated Thermosensitive Liposomes (Affisomes) for Improved Delivery of Anti-Cancer Agents
    Article Snippet: It is evident from the data (shown in ) that affibody-conjugation did not have an adverse effect on the time-dependent integrity of liposomes (control-III liposomes, 2.8–3.73%, Affisomes, 3.0–4.0%, days 0–18 respectively).

    Liposomes:

    Article Title: Targeting, bio distributive and tumor growth inhibiting characterization of anti-HER2 affibody coupling to liposomal doxorubicin using BALB/c mice bearing TUBO tumors.
    Article Snippet: Please cite this article as: Akhtari, Javad, Rezayat, Seyed Mahdi, Teymouri, Manouchehr, Alavizadeh, Seyedeh Hoda, Gheybi, Fatemeh, Badiee, Ali, Jaafari, Mahmoud Reza, Targeting, bio distributive and tumor growth inhibiting characterization of anti-HER2 affibody coupling to liposomal doxorubicin using BALB/c mice bearing TUBO tumors.International Journal of Pharmaceutics http://dx.doi.org/10.1016/j.ijpharm.2016.03.060

    Article Title: Artificial Scaffold Polypeptides As an Efficient Tool for the Targeted Delivery of Nanostructures In Vitro and In Vivo
    Article Snippet: .. Affisomes Compounds based on affibody-conjugated liposomes are known as affisomes [ , ]. .. A number of liposomes covalently modified with the ZHER2:342 anti-HER2 affibody [ ] and via a polyethyleneglycol linker (Z HER2:477 anti-HER2 affibody [ ], (Z 00477 ) 2 -Cys [ ], and (Z EGFR:955 ) 2 anti-EGFR affibody [ ]) have been obtained and used to treat HER2- and EGFR-positive tumors.



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