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accelerated rotarod test  (Panlab)

 
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    Structured Review

    Panlab accelerated rotarod test
    Accelerated Rotarod Test, supplied by Panlab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/accelerated+rotarod+test/apparatus+rotarod/pm42045381-83-15-19
    Average 86 stars, based on 1 article reviews
    accelerated rotarod test - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    Animal Model:

    Article Title: Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression
    Article Snippet: Motor coordination was assessed using the accelerated rotarod (Panlab 76-0772, Harvard apparatus) test.

    Article Title: TRPM7 kinase inhibitor TG100-115 provides neuroprotection against neonatal hypoxic-ischemic brain injury.
    Article Snippet: Hypoxic-ischemic brain injury (HIBI) is a major cause of perinatal brain damage, contributing to significant neonatal mortality and disability, yet its therapeutics remain limited.. Transient receptor potential melastatin 7 (TRPM7), a channel-kinase with kinase activity involved in neuronal death and neuroinflammation, has been implicated in ischemic and hypoxic brain damage.. Although the ion channel function of TRPM7 has been widely explored, the specific contribution of its kinase activity to HIBI pathophysiology remains poorly understood, mainly due to the lack of potent TRPM7 kinase inhibitors.

    Article Title: Electroacupuncture on the Scalp over the Motor Cortex Ameliorates Behavioral Deficits Following Neonatal Hypoxia-Ischemia in Rats via the Activation of Neural Stem Cells
    Article Snippet: The accelerated rotarod test was used to assess motor coordination and balance after HI (Panlab S.L.U., Barcelona, Spain).

    Staining:

    Article Title: Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression
    Article Snippet: Motor coordination was assessed using the accelerated rotarod (Panlab 76-0772, Harvard apparatus) test.

    Article Title: TRPM7 kinase inhibitor TG100-115 provides neuroprotection against neonatal hypoxic-ischemic brain injury.
    Article Snippet: Hypoxic-ischemic brain injury (HIBI) is a major cause of perinatal brain damage, contributing to significant neonatal mortality and disability, yet its therapeutics remain limited.. Transient receptor potential melastatin 7 (TRPM7), a channel-kinase with kinase activity involved in neuronal death and neuroinflammation, has been implicated in ischemic and hypoxic brain damage.. Although the ion channel function of TRPM7 has been widely explored, the specific contribution of its kinase activity to HIBI pathophysiology remains poorly understood, mainly due to the lack of potent TRPM7 kinase inhibitors.

    Article Title: Electroacupuncture on the Scalp over the Motor Cortex Ameliorates Behavioral Deficits Following Neonatal Hypoxia-Ischemia in Rats via the Activation of Neural Stem Cells
    Article Snippet: The accelerated rotarod test was used to assess motor coordination and balance after HI (Panlab S.L.U., Barcelona, Spain).



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    (A) Percentage of freezing detected in the cued task of the fear-conditioning assay in WT and TIMP2 KO mice (2-3 months of age, N = 12 mice per group). (B) Latency of TIMP2 KO and WT mice to fall in the <t>rotarod</t> in the fixed and (C) acceleration protocol at 4, 20 and 40 rpm (N = 12 mice per group). (D) Total distance traveled by TIMP2 KO and WT mice in the open field, as well as (E) velocity, and (F) percentage of time spent in the center of the arena (N = 11-12 mice per group). (G) Latency of TIMP2 KO and WT mice to fall in the wire test (N = 12 mice per group). (H) Time for TIMP2 KO and WT mice to descend the pole in the pole test (N = 11-12 mice per group). (I) Grip strength of the fore-, hind- and four limbs in TIMP2 KO and WT mice (N = 12 mice per group). (J) Hindlimb extension by clasping score in TIMP2 KO and WT mice (N = 10-11 mice per group). Data are represented as mean ± SEM. Student’s t -test for two-group comparisons. n.s., not significant.
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    (A) Percentage of freezing detected in the cued task of the fear-conditioning assay in WT and TIMP2 KO mice (2-3 months of age, N = 12 mice per group). (B) Latency of TIMP2 KO and WT mice to fall in the <t>rotarod</t> in the fixed and (C) acceleration protocol at 4, 20 and 40 rpm (N = 12 mice per group). (D) Total distance traveled by TIMP2 KO and WT mice in the open field, as well as (E) velocity, and (F) percentage of time spent in the center of the arena (N = 11-12 mice per group). (G) Latency of TIMP2 KO and WT mice to fall in the wire test (N = 12 mice per group). (H) Time for TIMP2 KO and WT mice to descend the pole in the pole test (N = 11-12 mice per group). (I) Grip strength of the fore-, hind- and four limbs in TIMP2 KO and WT mice (N = 12 mice per group). (J) Hindlimb extension by clasping score in TIMP2 KO and WT mice (N = 10-11 mice per group). Data are represented as mean ± SEM. Student’s t -test for two-group comparisons. n.s., not significant.
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    Image Search Results


    (A) Percentage of freezing detected in the cued task of the fear-conditioning assay in WT and TIMP2 KO mice (2-3 months of age, N = 12 mice per group). (B) Latency of TIMP2 KO and WT mice to fall in the rotarod in the fixed and (C) acceleration protocol at 4, 20 and 40 rpm (N = 12 mice per group). (D) Total distance traveled by TIMP2 KO and WT mice in the open field, as well as (E) velocity, and (F) percentage of time spent in the center of the arena (N = 11-12 mice per group). (G) Latency of TIMP2 KO and WT mice to fall in the wire test (N = 12 mice per group). (H) Time for TIMP2 KO and WT mice to descend the pole in the pole test (N = 11-12 mice per group). (I) Grip strength of the fore-, hind- and four limbs in TIMP2 KO and WT mice (N = 12 mice per group). (J) Hindlimb extension by clasping score in TIMP2 KO and WT mice (N = 10-11 mice per group). Data are represented as mean ± SEM. Student’s t -test for two-group comparisons. n.s., not significant.

    Journal: bioRxiv

    Article Title: Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity

    doi: 10.1101/2022.12.28.522138

    Figure Lengend Snippet: (A) Percentage of freezing detected in the cued task of the fear-conditioning assay in WT and TIMP2 KO mice (2-3 months of age, N = 12 mice per group). (B) Latency of TIMP2 KO and WT mice to fall in the rotarod in the fixed and (C) acceleration protocol at 4, 20 and 40 rpm (N = 12 mice per group). (D) Total distance traveled by TIMP2 KO and WT mice in the open field, as well as (E) velocity, and (F) percentage of time spent in the center of the arena (N = 11-12 mice per group). (G) Latency of TIMP2 KO and WT mice to fall in the wire test (N = 12 mice per group). (H) Time for TIMP2 KO and WT mice to descend the pole in the pole test (N = 11-12 mice per group). (I) Grip strength of the fore-, hind- and four limbs in TIMP2 KO and WT mice (N = 12 mice per group). (J) Hindlimb extension by clasping score in TIMP2 KO and WT mice (N = 10-11 mice per group). Data are represented as mean ± SEM. Student’s t -test for two-group comparisons. n.s., not significant.

    Article Snippet: Balance and motor function was measured using the fixed and standard accelerated rotarod test (Med Associates, St. Albans, VT).

    Techniques:

    (A) Percentage of freezing detected in the cued task of the fear-conditioning assay in TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice (2-3 months of age, N = 13-15 mice per group). (B) Latency of TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice to fall in the rotarod in the fixed and (C) acceleration protocol at 4, 10 and 20 rpm (N = 13-15 mice per group). (D) Total distance traveled by TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice in the open field, as well as (E) velocity, and (F) percentage of time spent in the center of the arena (N = 13-15 mice per group). (G) Latency of TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice to fall in the wire test (N = 12-14 mice per group). (H) Time for TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice to descend the pole in the pole test (N = 12-14 mice per group). (I) Grip strength of the fore-, hind- and four limbs in TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice (N = 13-15 mice per group). (J) Hindlimb extension by clasping score in TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice (N = 12-14 mice per group). Data are represented as mean ± SEM. Student’s t -test for two-group comparisons. n.s., not significant.

    Journal: bioRxiv

    Article Title: Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity

    doi: 10.1101/2022.12.28.522138

    Figure Lengend Snippet: (A) Percentage of freezing detected in the cued task of the fear-conditioning assay in TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice (2-3 months of age, N = 13-15 mice per group). (B) Latency of TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice to fall in the rotarod in the fixed and (C) acceleration protocol at 4, 10 and 20 rpm (N = 13-15 mice per group). (D) Total distance traveled by TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice in the open field, as well as (E) velocity, and (F) percentage of time spent in the center of the arena (N = 13-15 mice per group). (G) Latency of TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice to fall in the wire test (N = 12-14 mice per group). (H) Time for TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice to descend the pole in the pole test (N = 12-14 mice per group). (I) Grip strength of the fore-, hind- and four limbs in TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice (N = 13-15 mice per group). (J) Hindlimb extension by clasping score in TIMP2 fl/fl and Syn Cre/+ ; TIMP2 fl/fl mice (N = 12-14 mice per group). Data are represented as mean ± SEM. Student’s t -test for two-group comparisons. n.s., not significant.

    Article Snippet: Balance and motor function was measured using the fixed and standard accelerated rotarod test (Med Associates, St. Albans, VT).

    Techniques: