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jph203 s 2 amino 3  (MedChemExpress)


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    Structured Review

    MedChemExpress jph203 s 2 amino 3
    Determination of dissociation ( K D ) and inhibition constants ( K i ) of selected substrates and inhibitors for human 4F2hc-LAT1 by SPA. Competitive binding curves for determination of K D [L-leucine (A) , orange], and K i values [L-histidine (B) , light blue; BCH (C) , violet; <t>JPH203</t> (D) , green; T3 (E) , blue and T4 (F) , dark pink]. Determined K D and K i values, and 95% confidence intervals (CIs) are indicated. Mean ± standard deviation of normalized data from three independent experiments, each at least in triplicate, are shown. If not visible, error bars are smaller than symbols.
    Jph203 S 2 Amino 3, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/jph203 s 2 amino 3/product/MedChemExpress
    Average 91 stars, based on 2 article reviews
    jph203 s 2 amino 3 - by Bioz Stars, 2026-02
    91/100 stars

    Images

    1) Product Images from "Characterization of substrates and inhibitors of the human heterodimeric transporter 4F2hc-LAT1 using purified protein and the scintillation proximity radioligand binding assay"

    Article Title: Characterization of substrates and inhibitors of the human heterodimeric transporter 4F2hc-LAT1 using purified protein and the scintillation proximity radioligand binding assay

    Journal: Frontiers in Physiology

    doi: 10.3389/fphys.2023.1148055

    Determination of dissociation ( K D ) and inhibition constants ( K i ) of selected substrates and inhibitors for human 4F2hc-LAT1 by SPA. Competitive binding curves for determination of K D [L-leucine (A) , orange], and K i values [L-histidine (B) , light blue; BCH (C) , violet; JPH203 (D) , green; T3 (E) , blue and T4 (F) , dark pink]. Determined K D and K i values, and 95% confidence intervals (CIs) are indicated. Mean ± standard deviation of normalized data from three independent experiments, each at least in triplicate, are shown. If not visible, error bars are smaller than symbols.
    Figure Legend Snippet: Determination of dissociation ( K D ) and inhibition constants ( K i ) of selected substrates and inhibitors for human 4F2hc-LAT1 by SPA. Competitive binding curves for determination of K D [L-leucine (A) , orange], and K i values [L-histidine (B) , light blue; BCH (C) , violet; JPH203 (D) , green; T3 (E) , blue and T4 (F) , dark pink]. Determined K D and K i values, and 95% confidence intervals (CIs) are indicated. Mean ± standard deviation of normalized data from three independent experiments, each at least in triplicate, are shown. If not visible, error bars are smaller than symbols.

    Techniques Used: Inhibition, Binding Assay, Standard Deviation



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    MedChemExpress jph203 s 2 amino 3
    Determination of dissociation ( K D ) and inhibition constants ( K i ) of selected substrates and inhibitors for human 4F2hc-LAT1 by SPA. Competitive binding curves for determination of K D [L-leucine (A) , orange], and K i values [L-histidine (B) , light blue; BCH (C) , violet; <t>JPH203</t> (D) , green; T3 (E) , blue and T4 (F) , dark pink]. Determined K D and K i values, and 95% confidence intervals (CIs) are indicated. Mean ± standard deviation of normalized data from three independent experiments, each at least in triplicate, are shown. If not visible, error bars are smaller than symbols.
    Jph203 S 2 Amino 3, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/jph203 s 2 amino 3/product/MedChemExpress
    Average 91 stars, based on 1 article reviews
    jph203 s 2 amino 3 - by Bioz Stars, 2026-02
    91/100 stars
      Buy from Supplier

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    Determination of dissociation ( K D ) and inhibition constants ( K i ) of selected substrates and inhibitors for human 4F2hc-LAT1 by SPA. Competitive binding curves for determination of K D [L-leucine (A) , orange], and K i values [L-histidine (B) , light blue; BCH (C) , violet; JPH203 (D) , green; T3 (E) , blue and T4 (F) , dark pink]. Determined K D and K i values, and 95% confidence intervals (CIs) are indicated. Mean ± standard deviation of normalized data from three independent experiments, each at least in triplicate, are shown. If not visible, error bars are smaller than symbols.

    Journal: Frontiers in Physiology

    Article Title: Characterization of substrates and inhibitors of the human heterodimeric transporter 4F2hc-LAT1 using purified protein and the scintillation proximity radioligand binding assay

    doi: 10.3389/fphys.2023.1148055

    Figure Lengend Snippet: Determination of dissociation ( K D ) and inhibition constants ( K i ) of selected substrates and inhibitors for human 4F2hc-LAT1 by SPA. Competitive binding curves for determination of K D [L-leucine (A) , orange], and K i values [L-histidine (B) , light blue; BCH (C) , violet; JPH203 (D) , green; T3 (E) , blue and T4 (F) , dark pink]. Determined K D and K i values, and 95% confidence intervals (CIs) are indicated. Mean ± standard deviation of normalized data from three independent experiments, each at least in triplicate, are shown. If not visible, error bars are smaller than symbols.

    Article Snippet: The binding kinetics of hydrophobic compounds such as JPH203 [(S)-2-amino-3-(4-((5-amino-2-phenylbenzo [d] oxazol-7-yl)-methoxy)-3,5-dichlorophenyl)-propanoic acid] also known as KYT-0353 (MedChemExpress, Monmouth Junction, NJ, United States), and the thyroid hormones T3 (triiodothyronine) and T4 (thyroxine) (Sigma, St. Louis, MO, United States) were also determined by SPA.

    Techniques: Inhibition, Binding Assay, Standard Deviation