Review



betaxolol  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    MedChemExpress betaxolol
    Mitigation of β2-AR blockage on dry eye severity. ( A ) Schematic diagram of dry eye mice with ICI 118,551 (ICI), <t>Betaxolol,</t> Tamsulosin, or PBS treatment. ( B ) Measurement of tear secretion in mice with ICI treatment in dry eye mice ( n = 6 per group). ( C ) Corneal fluorescein staining and score at day 14 ( n = 6 per group). ( D , E ) Representative images and quantitative analysis of MMP3, MMP9, and TUNEL + cells in the corneal epithelium. Scale bar = 20 µm, n = 5 per group. ( F ) Representative immunohistochemical images of TNF-α and IL-1β. Scale bar = 20 µm. ( G ) Comparisons of protein levels of TNF-α and IL-1β in mouse corneas ( n = 5 per group). ( H ) Comparison of TNF-α and IL-1β mRNA transcripts in mouse corneas ( n = 5 per group). ( I ) Representative immunofluorescence images of the pan-neuronal marker TUBB3. Scale bar = 20 µm. ( J ) Comparison of NGF and Sema3a mRNA transcripts in mouse corneas ( n = 5 per group). ( K ) Comparisons of protein levels of TNF-α and IL-1β in mouse conjunctivae ( n = 5 per group). ( L ) PAS staining of conjunctival goblet cells and comparison of goblet cell density. Scale bar = 50 µm, n = 5 per group. ( M , N ) Effects of Betaxolol and Tamsulosin on tear secretion and corneal barrier ( n = 6 per group). Data are shown as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant.
    Betaxolol, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/betaxolol/product/MedChemExpress
    Average 94 stars, based on 5 article reviews
    betaxolol - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "Activation of Sympathetic Nervous System Drives Dry Eye Onset Via Norepinephrine-β2-Adrenergic Receptor Signaling in Mice"

    Article Title: Activation of Sympathetic Nervous System Drives Dry Eye Onset Via Norepinephrine-β2-Adrenergic Receptor Signaling in Mice

    Journal: Investigative Ophthalmology & Visual Science

    doi: 10.1167/iovs.66.6.13

    Mitigation of β2-AR blockage on dry eye severity. ( A ) Schematic diagram of dry eye mice with ICI 118,551 (ICI), Betaxolol, Tamsulosin, or PBS treatment. ( B ) Measurement of tear secretion in mice with ICI treatment in dry eye mice ( n = 6 per group). ( C ) Corneal fluorescein staining and score at day 14 ( n = 6 per group). ( D , E ) Representative images and quantitative analysis of MMP3, MMP9, and TUNEL + cells in the corneal epithelium. Scale bar = 20 µm, n = 5 per group. ( F ) Representative immunohistochemical images of TNF-α and IL-1β. Scale bar = 20 µm. ( G ) Comparisons of protein levels of TNF-α and IL-1β in mouse corneas ( n = 5 per group). ( H ) Comparison of TNF-α and IL-1β mRNA transcripts in mouse corneas ( n = 5 per group). ( I ) Representative immunofluorescence images of the pan-neuronal marker TUBB3. Scale bar = 20 µm. ( J ) Comparison of NGF and Sema3a mRNA transcripts in mouse corneas ( n = 5 per group). ( K ) Comparisons of protein levels of TNF-α and IL-1β in mouse conjunctivae ( n = 5 per group). ( L ) PAS staining of conjunctival goblet cells and comparison of goblet cell density. Scale bar = 50 µm, n = 5 per group. ( M , N ) Effects of Betaxolol and Tamsulosin on tear secretion and corneal barrier ( n = 6 per group). Data are shown as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant.
    Figure Legend Snippet: Mitigation of β2-AR blockage on dry eye severity. ( A ) Schematic diagram of dry eye mice with ICI 118,551 (ICI), Betaxolol, Tamsulosin, or PBS treatment. ( B ) Measurement of tear secretion in mice with ICI treatment in dry eye mice ( n = 6 per group). ( C ) Corneal fluorescein staining and score at day 14 ( n = 6 per group). ( D , E ) Representative images and quantitative analysis of MMP3, MMP9, and TUNEL + cells in the corneal epithelium. Scale bar = 20 µm, n = 5 per group. ( F ) Representative immunohistochemical images of TNF-α and IL-1β. Scale bar = 20 µm. ( G ) Comparisons of protein levels of TNF-α and IL-1β in mouse corneas ( n = 5 per group). ( H ) Comparison of TNF-α and IL-1β mRNA transcripts in mouse corneas ( n = 5 per group). ( I ) Representative immunofluorescence images of the pan-neuronal marker TUBB3. Scale bar = 20 µm. ( J ) Comparison of NGF and Sema3a mRNA transcripts in mouse corneas ( n = 5 per group). ( K ) Comparisons of protein levels of TNF-α and IL-1β in mouse conjunctivae ( n = 5 per group). ( L ) PAS staining of conjunctival goblet cells and comparison of goblet cell density. Scale bar = 50 µm, n = 5 per group. ( M , N ) Effects of Betaxolol and Tamsulosin on tear secretion and corneal barrier ( n = 6 per group). Data are shown as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant.

    Techniques Used: Staining, TUNEL Assay, Immunohistochemical staining, Comparison, Immunofluorescence, Marker



    Similar Products

    betaxolol  (MedChemExpress)
    94
    MedChemExpress betaxolol
    Mitigation of β2-AR blockage on dry eye severity. ( A ) Schematic diagram of dry eye mice with ICI 118,551 (ICI), <t>Betaxolol,</t> Tamsulosin, or PBS treatment. ( B ) Measurement of tear secretion in mice with ICI treatment in dry eye mice ( n = 6 per group). ( C ) Corneal fluorescein staining and score at day 14 ( n = 6 per group). ( D , E ) Representative images and quantitative analysis of MMP3, MMP9, and TUNEL + cells in the corneal epithelium. Scale bar = 20 µm, n = 5 per group. ( F ) Representative immunohistochemical images of TNF-α and IL-1β. Scale bar = 20 µm. ( G ) Comparisons of protein levels of TNF-α and IL-1β in mouse corneas ( n = 5 per group). ( H ) Comparison of TNF-α and IL-1β mRNA transcripts in mouse corneas ( n = 5 per group). ( I ) Representative immunofluorescence images of the pan-neuronal marker TUBB3. Scale bar = 20 µm. ( J ) Comparison of NGF and Sema3a mRNA transcripts in mouse corneas ( n = 5 per group). ( K ) Comparisons of protein levels of TNF-α and IL-1β in mouse conjunctivae ( n = 5 per group). ( L ) PAS staining of conjunctival goblet cells and comparison of goblet cell density. Scale bar = 50 µm, n = 5 per group. ( M , N ) Effects of Betaxolol and Tamsulosin on tear secretion and corneal barrier ( n = 6 per group). Data are shown as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant.
    Betaxolol, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/betaxolol/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    betaxolol - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier
    hy-b0381a  (medchemexpress)
    94
    medchemexpress hy-b0381a

    Hy B0381a, supplied by medchemexpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hy-b0381a/product/medchemexpress
    Average 94 stars, based on 1 article reviews
    hy-b0381a - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier
    hy b0381a  (MedChemExpress)
    94
    MedChemExpress hy b0381a

    Hy B0381a, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hy b0381a/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    hy b0381a - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier
    betaxolol hydrochloride  (MedChemExpress)
    94
    MedChemExpress betaxolol hydrochloride

    Betaxolol Hydrochloride, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/betaxolol hydrochloride/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    betaxolol hydrochloride - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Mitigation of β2-AR blockage on dry eye severity. ( A ) Schematic diagram of dry eye mice with ICI 118,551 (ICI), Betaxolol, Tamsulosin, or PBS treatment. ( B ) Measurement of tear secretion in mice with ICI treatment in dry eye mice ( n = 6 per group). ( C ) Corneal fluorescein staining and score at day 14 ( n = 6 per group). ( D , E ) Representative images and quantitative analysis of MMP3, MMP9, and TUNEL + cells in the corneal epithelium. Scale bar = 20 µm, n = 5 per group. ( F ) Representative immunohistochemical images of TNF-α and IL-1β. Scale bar = 20 µm. ( G ) Comparisons of protein levels of TNF-α and IL-1β in mouse corneas ( n = 5 per group). ( H ) Comparison of TNF-α and IL-1β mRNA transcripts in mouse corneas ( n = 5 per group). ( I ) Representative immunofluorescence images of the pan-neuronal marker TUBB3. Scale bar = 20 µm. ( J ) Comparison of NGF and Sema3a mRNA transcripts in mouse corneas ( n = 5 per group). ( K ) Comparisons of protein levels of TNF-α and IL-1β in mouse conjunctivae ( n = 5 per group). ( L ) PAS staining of conjunctival goblet cells and comparison of goblet cell density. Scale bar = 50 µm, n = 5 per group. ( M , N ) Effects of Betaxolol and Tamsulosin on tear secretion and corneal barrier ( n = 6 per group). Data are shown as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Activation of Sympathetic Nervous System Drives Dry Eye Onset Via Norepinephrine-β2-Adrenergic Receptor Signaling in Mice

    doi: 10.1167/iovs.66.6.13

    Figure Lengend Snippet: Mitigation of β2-AR blockage on dry eye severity. ( A ) Schematic diagram of dry eye mice with ICI 118,551 (ICI), Betaxolol, Tamsulosin, or PBS treatment. ( B ) Measurement of tear secretion in mice with ICI treatment in dry eye mice ( n = 6 per group). ( C ) Corneal fluorescein staining and score at day 14 ( n = 6 per group). ( D , E ) Representative images and quantitative analysis of MMP3, MMP9, and TUNEL + cells in the corneal epithelium. Scale bar = 20 µm, n = 5 per group. ( F ) Representative immunohistochemical images of TNF-α and IL-1β. Scale bar = 20 µm. ( G ) Comparisons of protein levels of TNF-α and IL-1β in mouse corneas ( n = 5 per group). ( H ) Comparison of TNF-α and IL-1β mRNA transcripts in mouse corneas ( n = 5 per group). ( I ) Representative immunofluorescence images of the pan-neuronal marker TUBB3. Scale bar = 20 µm. ( J ) Comparison of NGF and Sema3a mRNA transcripts in mouse corneas ( n = 5 per group). ( K ) Comparisons of protein levels of TNF-α and IL-1β in mouse conjunctivae ( n = 5 per group). ( L ) PAS staining of conjunctival goblet cells and comparison of goblet cell density. Scale bar = 50 µm, n = 5 per group. ( M , N ) Effects of Betaxolol and Tamsulosin on tear secretion and corneal barrier ( n = 6 per group). Data are shown as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant.

    Article Snippet: For the administration of AR antagonists, mice with dry eye were treated topically with ICI 118,551 (β2-AR antagonist, 20 micromolar [μM], MCE, HY-13951), Betaxolol (β1-AR antagonist, 10 mM, MCE, HY-B0381A), Tamsulosin (α1a-AR antagonist, 0.1 mM, MCE, HY-B0661) 4 times daily for a continuous period of 7 days.

    Techniques: Staining, TUNEL Assay, Immunohistochemical staining, Comparison, Immunofluorescence, Marker

    Journal: Cell Reports Methods

    Article Title: RECOVER identifies synergistic drug combinations in vitro through sequential model optimization

    doi: 10.1016/j.crmeth.2023.100599

    Figure Lengend Snippet:

    Article Snippet: Betaxolol (hydrochloride) , MedChem Express , HY-B0381A.

    Techniques: Software, Recombinant

    Journal: Cell Reports Methods

    Article Title: RECOVER identifies synergistic drug combinations in vitro through sequential model optimization

    doi: 10.1016/j.crmeth.2023.100599

    Figure Lengend Snippet:

    Article Snippet: Betaxolol (hydrochloride) , MedChem Express , HY-B0381A.

    Techniques: Software, Recombinant