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prazosin hydrochloride  (MedChemExpress)


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    MedChemExpress prazosin hydrochloride
    Prazosin Hydrochloride, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 18 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/prazosin hydrochloride/product/MedChemExpress
    Average 94 stars, based on 18 article reviews
    prazosin hydrochloride - by Bioz Stars, 2026-02
    94/100 stars

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    Effects of α- and β-adrenoceptor antagonists on NE-induced oxidative stress in VAFs of WKY and SHR. NE (20 μM) was administered 1 h after the application of α-receptor antagonist prazosin (10 μM) or β-receptor antagonist propranolol (3 μM). Measurements were made 4 h after the application of NE. (a) superoxide level. (b) bar graph showing the relative DHE fluorescence intensity. (c) representative images showing DHE fluorescent staining (red) of VAFs. Nuclei were stained with Hoechst33342 (blue). (d) NOX activity. (e) NOX2 protein expression. (f) representative images showing the NOX2 protein expressions. Values are mean ± SD. Two-way ANOVA followed by Bonferroni post hoc test. * P < 0.05 vs Ctrl; † P < 0.05 vs PBS; # P < 0.05 vs WKY. n = 6 in (a–d); n = 4 in e.

    Journal: Redox Report : Communications in Free Radical Research

    Article Title: Norepinephrine promotes oxidative stress in vascular adventitial fibroblasts via PKC/NFκB-mediated NOX2 upregulation

    doi: 10.1080/13510002.2025.2494314

    Figure Lengend Snippet: Effects of α- and β-adrenoceptor antagonists on NE-induced oxidative stress in VAFs of WKY and SHR. NE (20 μM) was administered 1 h after the application of α-receptor antagonist prazosin (10 μM) or β-receptor antagonist propranolol (3 μM). Measurements were made 4 h after the application of NE. (a) superoxide level. (b) bar graph showing the relative DHE fluorescence intensity. (c) representative images showing DHE fluorescent staining (red) of VAFs. Nuclei were stained with Hoechst33342 (blue). (d) NOX activity. (e) NOX2 protein expression. (f) representative images showing the NOX2 protein expressions. Values are mean ± SD. Two-way ANOVA followed by Bonferroni post hoc test. * P < 0.05 vs Ctrl; † P < 0.05 vs PBS; # P < 0.05 vs WKY. n = 6 in (a–d); n = 4 in e.

    Article Snippet: Norepinephrine bitartrate monohydrate, prazosin, propranolol, tempol, ML171, GSK2795039, GLX351322, BAY11-7082 and Go 6983 were bought from MCE (Monmouth Junction, NJ, USA).

    Techniques: Fluorescence, Staining, Activity Assay, Expressing

    Journal: iScience

    Article Title: Stimulation of TRPV1+ peripheral somatosensory nerves suppress inflammation via the somato-autonomic reflex

    doi: 10.1016/j.isci.2025.111831

    Figure Lengend Snippet:

    Article Snippet: Prazosin , MedChemExpress , Cat# HY-B0193A.

    Techniques: Recombinant, Cream, Enzyme-linked Immunosorbent Assay, RNAscope, Multiplex Assay, Software, Microscopy