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lurasidone hydrochloride  (MedChemExpress)


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    MedChemExpress lurasidone hydrochloride
    Lurasidone Hydrochloride, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/lurasidone hydrochloride/product/MedChemExpress
    Average 94 stars, based on 8 article reviews
    lurasidone hydrochloride - by Bioz Stars, 2026-02
    94/100 stars

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    Competition binding results from test ligands at [ 3 H]5-CT-labeled 5-HT7 receptors across experimental conditions; data are fit to a one-site fit K i model. Note the increased affinity of SB-269970 and lurasidone observed when incubations were performed in abECF (bottom) compared to SBB (top). Physiological temperature also modestly enhanced the affinity of SB-269970 and lurasidone.

    Journal: bioRxiv

    Article Title: Artificial Brain Extracellular Fluid in Radioligand Binding Assays: Effects on Affinities of Ligands at Serotonin 5-HT7 Receptors

    doi: 10.1101/2025.09.04.674239

    Figure Lengend Snippet: Competition binding results from test ligands at [ 3 H]5-CT-labeled 5-HT7 receptors across experimental conditions; data are fit to a one-site fit K i model. Note the increased affinity of SB-269970 and lurasidone observed when incubations were performed in abECF (bottom) compared to SBB (top). Physiological temperature also modestly enhanced the affinity of SB-269970 and lurasidone.

    Article Snippet: Radioligand competition binding assays were performed to evaluate the affinities of 5-CT maleate (Tocris), SB-269970 hydrochloride (Tocris), and lurasidone (MedChemExpress) ( ).

    Techniques: Binding Assay, Labeling

    Competition binding results from antagonist ligands at [ 3 H]5-CT-labeled 5-HT7 receptors across experimental conditions; data (same as in ) are fit to a two-site fit K i model. Note the increased affinity of SB-269970 and lurasidone observed when incubations were performed in abECF (bottom) compared to SBB (top). Physiological temperature also modestly enhanced the affinity of SB-269970 and lurasidone.

    Journal: bioRxiv

    Article Title: Artificial Brain Extracellular Fluid in Radioligand Binding Assays: Effects on Affinities of Ligands at Serotonin 5-HT7 Receptors

    doi: 10.1101/2025.09.04.674239

    Figure Lengend Snippet: Competition binding results from antagonist ligands at [ 3 H]5-CT-labeled 5-HT7 receptors across experimental conditions; data (same as in ) are fit to a two-site fit K i model. Note the increased affinity of SB-269970 and lurasidone observed when incubations were performed in abECF (bottom) compared to SBB (top). Physiological temperature also modestly enhanced the affinity of SB-269970 and lurasidone.

    Article Snippet: Radioligand competition binding assays were performed to evaluate the affinities of 5-CT maleate (Tocris), SB-269970 hydrochloride (Tocris), and lurasidone (MedChemExpress) ( ).

    Techniques: Binding Assay, Labeling