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netupitant  (MedChemExpress)


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    MedChemExpress netupitant
    Netupitant, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/netupitant/product/MedChemExpress
    Average 94 stars, based on 4 article reviews
    netupitant - by Bioz Stars, 2026-02
    94/100 stars

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    intravesical netupitant  (MedChemExpress)
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    MedChemExpress intravesical netupitant
    Effects of a neurokinin (NK)-1 receptor antagonist (RA), <t>netupitant,</t> on micturition reflex function from open outlet, continuous fill cystometry in NGF-OE mice and littermate WT mice at postnatal (P) day 7, P14, P28 and Adult (A). <t>Intravesical</t> netupitant (0.1 μg/ml) significantly (p ≤ 0.01) increased voided volume (A) and intercontraction interval (ICI) (B) in NGF-OE mice at all postnatal ages examined. Intravesical netupitant (0.1 μg/ml) was without effect on voided volume (A) or ICI (B) in WT mice except at P14 where there was a significant (p ≤ 0.01) increase in voided volume. *, p ≤ 0.01 compared to vehicle. Values are means ± S.E.M. (n = 6–8 for each group).
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    Effects of a neurokinin (NK)-1 receptor antagonist (RA), netupitant, on micturition reflex function from open outlet, continuous fill cystometry in NGF-OE mice and littermate WT mice at postnatal (P) day 7, P14, P28 and Adult (A). Intravesical netupitant (0.1 μg/ml) significantly (p ≤ 0.01) increased voided volume (A) and intercontraction interval (ICI) (B) in NGF-OE mice at all postnatal ages examined. Intravesical netupitant (0.1 μg/ml) was without effect on voided volume (A) or ICI (B) in WT mice except at P14 where there was a significant (p ≤ 0.01) increase in voided volume. *, p ≤ 0.01 compared to vehicle. Values are means ± S.E.M. (n = 6–8 for each group).

    Journal: Experimental neurology

    Article Title: Accelerated onset of the vesicovesical reflex in postnatal NGF-OE mice and the role of neuropeptides

    doi: 10.1016/j.expneurol.2016.06.021

    Figure Lengend Snippet: Effects of a neurokinin (NK)-1 receptor antagonist (RA), netupitant, on micturition reflex function from open outlet, continuous fill cystometry in NGF-OE mice and littermate WT mice at postnatal (P) day 7, P14, P28 and Adult (A). Intravesical netupitant (0.1 μg/ml) significantly (p ≤ 0.01) increased voided volume (A) and intercontraction interval (ICI) (B) in NGF-OE mice at all postnatal ages examined. Intravesical netupitant (0.1 μg/ml) was without effect on voided volume (A) or ICI (B) in WT mice except at P14 where there was a significant (p ≤ 0.01) increase in voided volume. *, p ≤ 0.01 compared to vehicle. Values are means ± S.E.M. (n = 6–8 for each group).

    Article Snippet: The effectiveness of intravesical netupitant (Med Chem Express (MCE), Monmouth Junction, NJ; 0.1 μg/ml) administration was evaluated in littermate WT and NGF-OE mice from various postnatal ages (P7-A).

    Techniques:

    Effects of a neurokinin (NK)-1 receptor antagonist (RA), netupitant, on micturition reflex function from open outlet, continuous fill cystometry in NGF-OE mice and littermate WT mice at postnatal (P) day 7, P14, P28 and Adult (A). Intravesical netupitant (0.1 μg/ml) significantly (p ≤ 0.01) decreased the number of nonvoiding contractions (NVCs) in NGF-OE mice at P7 and P28 but was without effect on NVCs in WT mice that exhibited few NVCs (A). Intravesical netupitant (0.1 μg/ml) was without effect on bladder pressures (baseline (BP), threshold pressure (TP), peak micturition pressure (MP)) in NGF-OE and WT mice at any postnatal age examined (B). *, p ≤ 0.01 compared to vehicle. Values are means ± S.E.M. (n = 6–8 for each group).

    Journal: Experimental neurology

    Article Title: Accelerated onset of the vesicovesical reflex in postnatal NGF-OE mice and the role of neuropeptides

    doi: 10.1016/j.expneurol.2016.06.021

    Figure Lengend Snippet: Effects of a neurokinin (NK)-1 receptor antagonist (RA), netupitant, on micturition reflex function from open outlet, continuous fill cystometry in NGF-OE mice and littermate WT mice at postnatal (P) day 7, P14, P28 and Adult (A). Intravesical netupitant (0.1 μg/ml) significantly (p ≤ 0.01) decreased the number of nonvoiding contractions (NVCs) in NGF-OE mice at P7 and P28 but was without effect on NVCs in WT mice that exhibited few NVCs (A). Intravesical netupitant (0.1 μg/ml) was without effect on bladder pressures (baseline (BP), threshold pressure (TP), peak micturition pressure (MP)) in NGF-OE and WT mice at any postnatal age examined (B). *, p ≤ 0.01 compared to vehicle. Values are means ± S.E.M. (n = 6–8 for each group).

    Article Snippet: The effectiveness of intravesical netupitant (Med Chem Express (MCE), Monmouth Junction, NJ; 0.1 μg/ml) administration was evaluated in littermate WT and NGF-OE mice from various postnatal ages (P7-A).

    Techniques: