Journal: Animals : an open access journal from MDPI
Article Title: Estradiol Reverses Ovariectomy-Induced Disruption of Hypothalamic Gene Expression and Behavior via Modulation of Gonadotropin Releasing Hormone and Calcium Signaling Pathways.
doi: 10.3390/ani15101467
Figure Lengend Snippet: Figure 10. An illustration of the GO enrichment analysis for the comparison groups. (A) CK_vs_E2, (B) CK_vs_OVX, (C) CK_vs_OVX+E2, (D) E2_vs_OVX, (E) E2_vs_OVX+E2, and (F) OVX_vs_OVX+E2, after ovariectomy and 17β-estradiol treatments. The analysis highlights molec- ular activities, cellular components, and biological processes. The treatments tested were CK (control), E2 (0.2 mg/kg dissolved in sesame oil), OVX (ovariectomized), and OVX+E2 (0.2 mg/kg dissolved in sesame oil).
Article Snippet: E2 was purchased from Med Chem Express (Nanjing, China) and dissolved in sesame oil.
Techniques: Comparison, Control