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zanamivir  (MedChemExpress)


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    Structured Review

    MedChemExpress zanamivir
    Zanamivir, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 28 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/zanamivir/product/MedChemExpress
    Average 94 stars, based on 28 article reviews
    zanamivir - by Bioz Stars, 2026-02
    94/100 stars

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    High resistance barrier of compound A5 in vitro . (A) Is a diagrammatic drawing representing the serial viral passage experiment by Figdraw. P0 refers to infecting MDCK cells with A/WSN/1933 at a multiplicity of infection (MOI) of 0.01. P ( n +1) refers to the infection of cells with the supernatant collected from P n , followed by the addition of the compound at its half-maximal effective concentration (EC 50 ) of P n. The EC 50 values were tested by cell counting kit 8 assay. (B) Shows the resistance curves of A5 , oseltamivir, and <t>baloxavir.</t> Data are mean ± SD, n = 3. (C) Is an antiviral curve of A5 against oseltamivir-resistant WSN. (D) Is an antiviral curve of A5 against baloxavir-resistant WSN. The curves were created with nonlinear regression analysis. Data are mean ± SD, n = 3.
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    High resistance barrier of compound A5 in vitro . (A) Is a diagrammatic drawing representing the serial viral passage experiment by Figdraw. P0 refers to infecting MDCK cells with A/WSN/1933 at a multiplicity of infection (MOI) of 0.01. P ( n +1) refers to the infection of cells with the supernatant collected from P n , followed by the addition of the compound at its half-maximal effective concentration (EC 50 ) of P n. The EC 50 values were tested by cell counting kit 8 assay. (B) Shows the resistance curves of A5 , oseltamivir, and baloxavir. Data are mean ± SD, n = 3. (C) Is an antiviral curve of A5 against oseltamivir-resistant WSN. (D) Is an antiviral curve of A5 against baloxavir-resistant WSN. The curves were created with nonlinear regression analysis. Data are mean ± SD, n = 3.

    Journal: Acta Pharmaceutica Sinica. B

    Article Title: A novel C-3-substituted oleanolic acid benzyl amide derivative exhibits therapeutic potential against influenza A by targeting PA–PB1 interactions and modulating host macrophage inflammation

    doi: 10.1016/j.apsb.2025.05.031

    Figure Lengend Snippet: High resistance barrier of compound A5 in vitro . (A) Is a diagrammatic drawing representing the serial viral passage experiment by Figdraw. P0 refers to infecting MDCK cells with A/WSN/1933 at a multiplicity of infection (MOI) of 0.01. P ( n +1) refers to the infection of cells with the supernatant collected from P n , followed by the addition of the compound at its half-maximal effective concentration (EC 50 ) of P n. The EC 50 values were tested by cell counting kit 8 assay. (B) Shows the resistance curves of A5 , oseltamivir, and baloxavir. Data are mean ± SD, n = 3. (C) Is an antiviral curve of A5 against oseltamivir-resistant WSN. (D) Is an antiviral curve of A5 against baloxavir-resistant WSN. The curves were created with nonlinear regression analysis. Data are mean ± SD, n = 3.

    Article Snippet: Zanamivir, oseltamivir phosphate, favipiravir, and baloxavir were purchased from MedChemExpress (NJ, USA).

    Techniques: In Vitro, Infection, Concentration Assay, Cell Counting