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anakinra  (MedChemExpress)


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    MedChemExpress anakinra
    Anakinra, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 72 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anakinra/product/MedChemExpress
    Average 95 stars, based on 72 article reviews
    anakinra - by Bioz Stars, 2026-02
    95/100 stars

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    Anakinra exerts potential therapeutic effects on a MASH mouse model. ( A ) Therapeutic schedule of anakinra treatment in the MASH mouse model and changes in body weight and serum ALT levels before and after treatment. ( B ) Histological evaluation of liver tissues (n = 8 mice/group). ( C ) Inflammation and fibrosis-related gene expression in liver tissues (n = 8 mice/group).

    Journal: Cellular and Molecular Gastroenterology and Hepatology

    Article Title: Liver Sinusoidal Endothelial Cells Promote Metabolic Dysfunction-associated Steatohepatitis Progression via Interleukin-1R1-mediated Chemokine Production Induced by Macrophage-derived Interleukin-1β

    doi: 10.1016/j.jcmgh.2025.101698

    Figure Lengend Snippet: Anakinra exerts potential therapeutic effects on a MASH mouse model. ( A ) Therapeutic schedule of anakinra treatment in the MASH mouse model and changes in body weight and serum ALT levels before and after treatment. ( B ) Histological evaluation of liver tissues (n = 8 mice/group). ( C ) Inflammation and fibrosis-related gene expression in liver tissues (n = 8 mice/group).

    Article Snippet: We performed an experiment using the pharmacological inhibitor anakinra (Raleukin; Synonyms: Kineret; Anakinra; HY-108841; MedChemExpress) to evaluate the therapeutic effect of IL1R1 signaling on MASH progression.

    Techniques: Gene Expression