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hy19707  (MedChemExpress)


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    Structured Review

    MedChemExpress hy19707
    Hy19707, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 95 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/4%CE%BC8c/4%CE%BC8C/pm42304385-88-3-4
    Average 95 stars, based on 95 article reviews
    hy19707 - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Incubation:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Cell Culture:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Recombinant:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Virus:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Protease Inhibitor:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Polymerase Chain Reaction:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Transfection:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Cleavage Assay:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used

    Isolation:

    Article Title: The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.
    Article Snippet: rum, 1% penicillin/streptomycin, and mycoplasma elimination reagent (40607ES03, YEASON) to ensure regular mycoplasma test results were negative. ER stress inducer Tunicamycin (2.5μM for 24h; HY-A0098, MedChemExpress), ER pathways inhibitors ISRIB (0.5μM for 24h; HY-12495A, MedChemExpress), 4μ8C (50μM for 24h; HY-19707, MedChemExpress) and Ceapin-A7 (2μM for 24h; HY-108434, MedChemExpress) were used



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    Image Search Results


    ER stress inducers promote keretinocyte differentiation partially through UPR activation. Primary mouse keretinocyte were treated with UPR pathway inhibitors: 4μ8C or Kira 6 (IRE1/XPB1 inhibitors), GSK2606414 or GSK2656157 (PERK inhibitors) with or without TM (a and b) or BFA (c and d) for 48 h, followed by detection of ER stress and differentiation markers. Data are mean ± SEM. ns: not significant, ** P < 0.01, *** P < 0.001, **** P < 0.0001.

    Journal: Cell Stress & Chaperones

    Article Title: Activation of unfolded protein response pathways promotes keratinocyte differentiation and ameliorates psoriasis phenotypes

    doi: 10.1016/j.cstres.2026.100163

    Figure Lengend Snippet: ER stress inducers promote keretinocyte differentiation partially through UPR activation. Primary mouse keretinocyte were treated with UPR pathway inhibitors: 4μ8C or Kira 6 (IRE1/XPB1 inhibitors), GSK2606414 or GSK2656157 (PERK inhibitors) with or without TM (a and b) or BFA (c and d) for 48 h, followed by detection of ER stress and differentiation markers. Data are mean ± SEM. ns: not significant, ** P < 0.01, *** P < 0.001, **** P < 0.0001.

    Article Snippet: The IRE1α inhibitor 4μ8C (Selleck, S7272) and Kira6 (Selleck, S8658), as well as the PERK inhibitors GSK2606414 (Selleck, S7307) or GSK2656157 (Selleck, S7033), were dissolved in DMSO and used at a final concentration of 4μ8C 1 mM, Kira6 5 μM, GSK2606414 140 μM, GSK2656157 3 μM.

    Techniques: Activation Assay