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1307007s  (ATCC)


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    Structured Review

    ATCC 1307007s
    In vitro and in vivo activities of GSK1322322 against S. pneumoniae , H. influenzae , and S. aureus isolates
    1307007s, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/1307007s/product/ATCC
    Average 90 stars, based on 2 article reviews
    1307007s - by Bioz Stars, 2026-06
    90/100 stars

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    1) Product Images from "Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae , Haemophilus influenzae , and Staphylococcus aureus in Rodent Models of Infection"

    Article Title: Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae , Haemophilus influenzae , and Staphylococcus aureus in Rodent Models of Infection

    Journal: Antimicrobial Agents and Chemotherapy

    doi: 10.1128/AAC.01842-15

    In vitro and in vivo activities of GSK1322322 against S. pneumoniae , H. influenzae , and S. aureus isolates
    Figure Legend Snippet: In vitro and in vivo activities of GSK1322322 against S. pneumoniae , H. influenzae , and S. aureus isolates

    Techniques Used: In Vitro, In Vivo



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    90
    ATCC 1307007s
    In vitro and in vivo activities of GSK1322322 against S. pneumoniae , H. influenzae , and S. aureus isolates
    1307007s, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/1307007s/product/ATCC
    Average 90 stars, based on 1 article reviews
    1307007s - by Bioz Stars, 2026-06
    90/100 stars
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    In vitro and in vivo activities of GSK1322322 against S. pneumoniae , H. influenzae , and S. aureus isolates

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae , Haemophilus influenzae , and Staphylococcus aureus in Rodent Models of Infection

    doi: 10.1128/AAC.01842-15

    Figure Lengend Snippet: In vitro and in vivo activities of GSK1322322 against S. pneumoniae , H. influenzae , and S. aureus isolates

    Article Snippet: TABLE 2 Organism MIC (μg/ml) R 2 for line fit (%) Stasis 1-log 10 reduction Max killing (log 10 reduction) f AUC f AUC/MIC f AUC f AUC/MIC S. pneumoniae 10127 0.25 99.9 2.0 8.1 3.6 14.4 2.8 1316009S 0.25 96.1 6.5 26.0 15.1 60.3 1.8 ATCC 10813 0.5 100 8.4 16.9 22.2 44.5 1.2 1307007S 1 95.8 16.1 16.1 20.1 20.1 2.7 ATCC 6303 1 99.8 19.8 19.8 24.8 24.8 2.8 1629 2 100 15.8 7.9 21.2 10.6 2.4 298443 2 99.9 26.5 13.2 31.0 15.5 2.3 336808 2 86 8.2 4.2 19.0 9.5 2.6 338860 2 99.5 2.9 1.5 6.7 3.4 2.8 340449 2 94.6 8.0 4.0 14.9 7.4 2.1 L11259 2 100 7.1 3.5 9.0 4.5 2.0 Mean ± SD NA d NA 11.0 ± 7.5 11.0 ± 7.9 17.0 ± 8.2 19.5 ± 17.8 2.3 ± 0.5 Median NA NA 8.2 8.1 19.0 14.4 2.4 H. influenzae 1998-100-126H 1 99.7 7.3 7.3 13.4 13.4 2.9 503-008H 1 99.8 7.1 7.1 13.9 13.9 2.7 08003H 2 99.9 14.5 7.2 16.7 8.3 2.7 H128 2 96.6 15.3 7.6 26.0 13.0 2.7 19001H 4 91.9 14.8 3.7 37.3 9.3 3.0 Mean ± SD NA NA 11.8 ± 4.2 6.6 ± 1.6 21.5 ± 10.2 11.6 ± 2.6 2.8 ± 0.1 Median NA NA 14.5 7.2 16.7 13.0 2.7 S. aureus 1312007A 0.5 96.6 3.9 7.8 9.0 17.9 1.8 1307005A a 0.5 98.9 3.8 7.6 7.7 15.5 2.0 X32601 a , b , c 1 99.8 1.6 1.6 4.3 4.3 3.2 1309006 a 1 99.7 0.2 0.2 2.3 2.3 2.9 PVL-2 a , b 2 99.2 1.9 0.9 5.5 2.8 3.4 PK-2 2 97 2.3 1.1 14.2 7.1 2.5 A-24 4 99.9 2.7 0.7 3.8 1.0 3.1 T63256 a , b , c 4 99.9 2.0 0.5 7.1 1.8 3.4 Mean ± SD NA NA 2.3 ± 1.2 2.6 ± 3.2 6.7 ± 3.7 6.6 ± 6.6 2.8 ± 0.6 Median NA NA 2.1 1.0 6.3 3.5 3.0 Open in a separate window a Macrolide resistant. b Methicillin resistant. c Quinolone resistant. d NA, not applicable.

    Techniques: In Vitro, In Vivo