interactive web-based tools (Novartis)
90
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Novartis
interactive web-based tools
Interactive Web Based Tools, supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/web-based+interactive+tools/web+tool/pm22436390-64-35-34
Average 90 stars, based on 1 article reviews
Interactive Web Based Tools, supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/web-based+interactive+tools/web+tool/pm22436390-64-35-34
Average 90 stars, based on 1 article reviews
interactive web-based tools - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Applications of self-organizing neural networks in virtual screening and diversity selection. Article Snippet: Artificial neural networks provide a powerful technique for the analysis and modeling of nonlinear relationships between molecular structures and pharmacological activity.. Many network types, including Kohonen and counterpropagation, also provide an intuitive method for the visual assessment of correspondence between the input and output data.. This work shows how a combination of neural networks and radial distribution function molecular descriptors can be applied in various areas of industrial pharmaceutical research. Article Title: Bioisosteric Replacement and Scaffold Hopping in Lead Generation and Optimization. Article Snippet: The twin concepts of bioisosteric replacement and scaffold hopping (or lead hopping) are widely used techniques in medicinal chemistry.. They can be defined generally as the replacement of a part of a bioactive molecule with a substructure that is similar in size and exhibits similar properties.. Bioisosteric transformations are used in the process of lead optimization to improve the properties of potential drug candidates, such as selectivity or transport characteristics, or to remove unwanted side effects such as toxicity and metabolic liabilities. Article Title: Database of bioactive ring systems with calculated properties and its use in bioisosteric design and scaffold hopping. Article Snippet: 0968-0896/$ see front matter 2012 Elsevier Ltd. A doi:10.1016/j.bmc.2012.02.058 ⇑ Corresponding author.. E-mail address: peter.ertl@novartis.com URL: http://peter-ertl.com A system for identification of bioisosteric scaffolds is presented.. The system uses a database of over 7000 scaffolds extracted from bioactive molecules. Article Title: Health assessment of commercial drivers: a meta-narrative systematic review Article Snippet: • I believe this was Operation Downshift and sponsored by a pharma company but did it have a relationship to crash or just passing the exam. in other parts of paper discussed crash -need to choose an endpoint you are evaluating Authors’ response: The program is a free Article Title: Estimation of pKa for druglike compounds using semiempirical and information-based descriptors. Article Snippet: A pragmatic approach has been developed for the estimation of aqueous ionization constants (pKa) for druglike compounds.. The method involves an algorithm that assigns ionization constants in a stepwise manner to the acidic and basic groups present in a compound.. Predictions are made for each ionizable group using models derived from semiempirical quantum chemical properties and information-based descriptors. Article Title: Web-based cheminformatics and molecular property prediction tools supporting drug design and development at Novartis. Article Snippet: This article was downloaded by: [University of Saskatchewan Library] On: 06 June 2012, At: 05:48 Publisher: Taylor & Francis Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK SAR and QSAR in Environmental Research Publication details, including instructions for authors and subscription information: http://www.tandfonline.com/loi/gsar20 Web-based cheminformatics and molecular property prediction tools supporting drug design and development at Novartis P. Ertl, J. Mühlbacher, B. Rohde & P. Selzer a Novartis Institute for Biomedical Research, WKL-125.14.20, CH-4002, Basel, Switzerland Available online: 01 Feb 2007 To cite this article: P. Ertl, J. Mühlbacher, B. Rohde & P. Selzer (2003): Web-based cheminformatics and molecular property prediction tools supporting drug design and development at Novartis, SAR and QSAR in Environmental Research, 14:5-6, 321-328 To link to this article: http://dx.doi.org/10.1080/10629360310001673917 PLEASE SCROLL DOWN FOR ARTICLE Full terms and conditions of use: http://www.tandfonline.com/page/terms-and-conditions This article may be used for research, teaching, and private study purposes.. Any substantial or systematic reproduction, redistribution, reselling, loan, sub-licensing, systematic supply, or distribution in any form to anyone is expressly forbidden.. The publisher does not give any warranty express or implied or make any representation that the contents will be complete or accurate or up to date. Functional Assay:Article Title: BioisoIdentifier: an online free tool to investigate local structural replacements from PDB. Article Snippet: .. A web tool to automate |
