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software program transfac  (Qiagen)


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    Structured Review

    Qiagen software program transfac
    21 target genes of Hypoxia-inducible factor 1α (HIF-1α) out of 216 DEGs in diabetic mice through <t> TRANSFAC </t> ® .
    Software Program Transfac, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/transfac+program/transfac+software/pmc06412638-65-3-5
    Average 90 stars, based on 1 article reviews
    software program transfac - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein"

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein

    Journal: Molecules

    doi: 10.3390/molecules24040760

    21 target genes of Hypoxia-inducible factor 1α (HIF-1α) out of 216 DEGs in diabetic mice through  TRANSFAC  ® .
    Figure Legend Snippet: 21 target genes of Hypoxia-inducible factor 1α (HIF-1α) out of 216 DEGs in diabetic mice through TRANSFAC ® .

    Techniques Used: Binding Assay, Membrane, Ubiquitin Proteomics

    Related Articles

    Binding Assay:

    Article Title: A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors
    Article Snippet: We used a professional version of TRANSFAC (BIOBASE, Qiagen) software to identify transcriptional factors and RESs in the promote region (+500 bp around the TSS) of 113 genes with poised POL II binding sites in high HER2-expressing breast cancer cell lines and differentially expressed in HER2+/− breast cancer tissues ( e.g. tissue context dependen t) [ , ].

    Article Title: lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms
    Article Snippet: Transcription factor binding sites enriched in DRAIR promoter were analyzed using TRANSFAC software (Qiagen).

    Article Title: The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: The autotaxin-LPA 2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates estrogen-induced visceral hypersensitivity
    Article Snippet: We searched putative cis -elements within ±2Kb of the TSS using TRANSFAC software (BIOBASE Biological Database, Qiagen, Frederick, MD, USA) and designed primers to cover five regions containing motifs for potential positive transcription factors ( ).

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Software:

    Article Title: A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors
    Article Snippet: We used a professional version of TRANSFAC (BIOBASE, Qiagen) software to identify transcriptional factors and RESs in the promote region (+500 bp around the TSS) of 113 genes with poised POL II binding sites in high HER2-expressing breast cancer cell lines and differentially expressed in HER2+/− breast cancer tissues ( e.g. tissue context dependen t) [ , ].

    Article Title: lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms
    Article Snippet: Transcription factor binding sites enriched in DRAIR promoter were analyzed using TRANSFAC software (Qiagen).

    Article Title: The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: The autotaxin-LPA 2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates estrogen-induced visceral hypersensitivity
    Article Snippet: We searched putative cis -elements within ±2Kb of the TSS using TRANSFAC software (BIOBASE Biological Database, Qiagen, Frederick, MD, USA) and designed primers to cover five regions containing motifs for potential positive transcription factors ( ).

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Membrane:

    Article Title: A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors
    Article Snippet: We used a professional version of TRANSFAC (BIOBASE, Qiagen) software to identify transcriptional factors and RESs in the promote region (+500 bp around the TSS) of 113 genes with poised POL II binding sites in high HER2-expressing breast cancer cell lines and differentially expressed in HER2+/− breast cancer tissues ( e.g. tissue context dependen t) [ , ].

    Article Title: lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms
    Article Snippet: Transcription factor binding sites enriched in DRAIR promoter were analyzed using TRANSFAC software (Qiagen).

    Article Title: The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: The autotaxin-LPA 2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates estrogen-induced visceral hypersensitivity
    Article Snippet: We searched putative cis -elements within ±2Kb of the TSS using TRANSFAC software (BIOBASE Biological Database, Qiagen, Frederick, MD, USA) and designed primers to cover five regions containing motifs for potential positive transcription factors ( ).

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Ubiquitin Proteomics:

    Article Title: A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors
    Article Snippet: We used a professional version of TRANSFAC (BIOBASE, Qiagen) software to identify transcriptional factors and RESs in the promote region (+500 bp around the TSS) of 113 genes with poised POL II binding sites in high HER2-expressing breast cancer cell lines and differentially expressed in HER2+/− breast cancer tissues ( e.g. tissue context dependen t) [ , ].

    Article Title: lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms
    Article Snippet: Transcription factor binding sites enriched in DRAIR promoter were analyzed using TRANSFAC software (Qiagen).

    Article Title: The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: The autotaxin-LPA 2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates estrogen-induced visceral hypersensitivity
    Article Snippet: We searched putative cis -elements within ±2Kb of the TSS using TRANSFAC software (BIOBASE Biological Database, Qiagen, Frederick, MD, USA) and designed primers to cover five regions containing motifs for potential positive transcription factors ( ).

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    In Silico:

    Article Title: A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors
    Article Snippet: We used a professional version of TRANSFAC (BIOBASE, Qiagen) software to identify transcriptional factors and RESs in the promote region (+500 bp around the TSS) of 113 genes with poised POL II binding sites in high HER2-expressing breast cancer cell lines and differentially expressed in HER2+/− breast cancer tissues ( e.g. tissue context dependen t) [ , ].

    Article Title: lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms
    Article Snippet: Transcription factor binding sites enriched in DRAIR promoter were analyzed using TRANSFAC software (Qiagen).

    Article Title: The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: The autotaxin-LPA 2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates estrogen-induced visceral hypersensitivity
    Article Snippet: We searched putative cis -elements within ±2Kb of the TSS using TRANSFAC software (BIOBASE Biological Database, Qiagen, Frederick, MD, USA) and designed primers to cover five regions containing motifs for potential positive transcription factors ( ).

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Sequencing:

    Article Title: A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors
    Article Snippet: We used a professional version of TRANSFAC (BIOBASE, Qiagen) software to identify transcriptional factors and RESs in the promote region (+500 bp around the TSS) of 113 genes with poised POL II binding sites in high HER2-expressing breast cancer cell lines and differentially expressed in HER2+/− breast cancer tissues ( e.g. tissue context dependen t) [ , ].

    Article Title: lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms
    Article Snippet: Transcription factor binding sites enriched in DRAIR promoter were analyzed using TRANSFAC software (Qiagen).

    Article Title: The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: The autotaxin-LPA 2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair
    Article Snippet: To elucidate the transcription-factor pathway responsible for the upregulation of the lpa2 gene, we performed an in silico search using the Transfac software (Qiagen) for predicted transcription factor binding sites in the human lpa2 promoter.

    Article Title: Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates estrogen-induced visceral hypersensitivity
    Article Snippet: We searched putative cis -elements within ±2Kb of the TSS using TRANSFAC software (BIOBASE Biological Database, Qiagen, Frederick, MD, USA) and designed primers to cover five regions containing motifs for potential positive transcription factors ( ).

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein
    Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.



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    Image Search Results


    21 target genes of Hypoxia-inducible factor 1α (HIF-1α) out of 216 DEGs in diabetic mice through  TRANSFAC  ® .

    Journal: Molecules

    Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein

    doi: 10.3390/molecules24040760

    Figure Lengend Snippet: 21 target genes of Hypoxia-inducible factor 1α (HIF-1α) out of 216 DEGs in diabetic mice through TRANSFAC ® .

    Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

    Techniques: Binding Assay, Membrane, Ubiquitin Proteomics