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Genomatix gmbh transfac software
Transfac Software, supplied by Genomatix gmbh, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/transfac+program/transfac+software/pm18477455-280-19-21
Average 90 stars, based on 1 article reviews
transfac software - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Feedback inhibition of Jak/STAT signaling by apontic is required to limit an invasive cell population.
Article Snippet: Electrophoretic Mobility Shift Assay, EMSA To identify putative STAT binding sites in slbo and apt regulatory regions, we used Transfac software (http://www.genomatix.de/cgi-bin/gems/launch.pl).

Article Title: MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer
Article Snippet: To dissect the molecular mechanism for the transcriptional activation of mir-183-96-182 cluster by miR-155, we used TransFac and Genomatix softwares 7 to search for potential transcription-factor-binding sites in the promoter and found a putative binding site for Ets-1, a known miR-155 target 8 , located within P mir-183-96-182 ( , top).

Article Title: Tumor suppressor protein p53 exerts negative transcriptional regulation on human sodium iodide symporter gene expression in breast cancer.
Article Snippet: Purpose Aberrant expression of human sodium iodide symporter (NIS) in breast cancer (BC) is well documented but the transcription factors (TF) regulating its aberrant expression is poorly known.. We identify the presence of three p53 binding sites on the human NIS promoter sequence by conducting genome-wide TF analysis, and further investigate their regulatory role.. Methods The differences in transcription and translation were measured by real-time PCR, luciferase reporter assay, site-directed mutagenesis, in vivo optical imaging, and chromatin immunoprecipitation.

Article Title: Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation.
Article Snippet: Further, in silico analysis (using Genomatix and Transfac Software) as well as promoter binding array results provide confirmation on the presence of TF binding sites on NIS promoter (as listed in Table 2) supporting their potential direct role in modulating cellular NIS expression.

Article Title: MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo
Article Snippet: The conserved predicted binding sites for ETS factors in the R2 module of the nodal promoter [ ] were identified using the TransFac software and the MatInspector software from Genomatix.

Binding Assay:

Article Title: Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERα and growth factors via MAPK pathway
Article Snippet: Further analysis using Bioinformatics and Molecular Analysis Section (BIMAS) ProScan software [ ] was used to identify putative promoter sequences in this region of DNA. .. The VISTA Genome Browser [ ] was used to generate homology plots, whereas analysis using Genomatix TRANSFAC software analysis (Genomatix, Munich, Germany) identified binding sites for transcription factors in the putative promoter sequences. ..



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21 target genes of Hypoxia-inducible factor 1α (HIF-1α) out of 216 DEGs in diabetic mice through  TRANSFAC  ® .

Journal: Molecules

Article Title: Therapeutic Effects of HIF-1α on Bone Formation around Implants in Diabetic Mice Using Cell-Penetrating DNA-Binding Protein

doi: 10.3390/molecules24040760

Figure Lengend Snippet: 21 target genes of Hypoxia-inducible factor 1α (HIF-1α) out of 216 DEGs in diabetic mice through TRANSFAC ® .

Article Snippet: The software program, TRANSFAC ® (Qiagen N.V., Valencia, CA, USA), was used to select the target genes of HIF-1α.

Techniques: Binding Assay, Membrane, Ubiquitin Proteomics