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Caris Life Sciences transcriptome sequencing wts data
Transcriptome Sequencing Wts Data, supplied by Caris Life Sciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/transcriptome+data/sequencing+transcriptome+whole/pm42236117-215-17-22
Average 86 stars, based on 1 article reviews
transcriptome sequencing wts data - by Bioz Stars, 2026-09
86/100 stars

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Sequencing:

Article Title: Genomic landscape, immune microenvironment and survival in male versus female breast cancer
Article Snippet: .. We analyzed whole-transcriptome (WTS) and whole exome sequencing from 19 697 deidentified tumor samples provided to Caris Life Sciences. ..

Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

Article Title: Spatially resolved single-cell landscape of tumor immunotypes reveals the central role of interferon signaling and plasmacytoid dendritic cells in triple-negative breast cancer.
Article Snippet: In collaboration with Caris Life Sciences (Phoenix, AZ), we used the CODEai data platform and identified a cohort of 2899 patients with TNBC with available genomic and clinical outcome data (demographic characteristics summarized in online supplemental table S11). .. Within the CODEai data platform, we applied a transcriptomic deconvolution approach to estimate pDC abundance from whole transcriptome sequencing (WTS) data (NovaSeq; Caris Life Sciences, Phoenix, AZ). ..

Article Title: DICER1-mutated renal neoplasia: A series of 5 cases demonstrating the spectrum of cystic nephroma, Wilms tumor, and anaplastic sarcoma.
Article Snippet: Objectives: The DICER1 gene encodes a ribonuclease essential for microRNA processing and regulates diverse cellular functions.. Germline DICER1 alterations underlie DICER1-related tumor predisposition syndrome, which can lead to renal neoplasia.. Herein, we studied the spectrum of DICER1-altered renal neoplasia.

Article Title: Proactive identification of candidates for newly approved targeted therapies using a clinical decision support program
Article Snippet: .. Between 2018 and 2025, tumor samples were submitted to Caris Life Sciences for whole-exome sequencing, whole-transcriptome sequencing, and immunohistochemistry. ..

Article Title: Genomic landscape, immune microenvironment and survival in male versus female breast cancer.
Article Snippet: .. Materials and methods: We analyzed whole-transcriptome (WTS) and whole exome sequencing from 19 697 deidentified tumor samples provided to Caris Life Sciences. ..

Biomarker Discovery:

Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

Next-Generation Sequencing:

Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

Article Title: DICER1-mutated renal neoplasia: A series of 5 cases demonstrating the spectrum of cystic nephroma, Wilms tumor, and anaplastic sarcoma.
Article Snippet: Objectives: The DICER1 gene encodes a ribonuclease essential for microRNA processing and regulates diverse cellular functions.. Germline DICER1 alterations underlie DICER1-related tumor predisposition syndrome, which can lead to renal neoplasia.. Herein, we studied the spectrum of DICER1-altered renal neoplasia.

Mutagenesis:

Article Title: Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment
Article Snippet: .. To confirm the diagnosis, molecular testing (next-generation sequencing (NGS); whole exome and whole transcriptome sequencing, Caris Life Sciences (Irving, Texas, United States)) revealed an S419P mutation in the FH gene, along with pathogenic mutations in KMT2A , NF2 , and TP53 , discussed in greater detail below. .. Germline testing (Ambry Genetics CancerNext-Expanded ® + RNAinsight ® 71 gene panel) confirmed the S419P mutation to be in the germline.

Immunohistochemistry:

Article Title: Proactive identification of candidates for newly approved targeted therapies using a clinical decision support program
Article Snippet: .. Between 2018 and 2025, tumor samples were submitted to Caris Life Sciences for whole-exome sequencing, whole-transcriptome sequencing, and immunohistochemistry. ..



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a) Log 2 ([elevated temperature/control] average total accumulation) of metabolic categories (n≥3) at six different seed developmental stages. b) Untargeted metabolomic data statistical analysis. c) Differentially accumulated metabolic features during seed development. d) Number of major metabolic categories (Flavonoids, Cinnamic acids and derivatives, and Glucosinolates) induced by elevated temperature at each seed developmental stage. e) Transcriptomic data statistical analysis. f) Differentially expressed genes during seed development. g) Percentages of genes coding for enzymes putatively involved in specialized metabolite modifications (Acyltransferases, Glycosyltransferases, Hydroxylases and Methyltransferases) induced, and repressed, at each seed developmental stage by elevated temperature.

Journal: bioRxiv

Article Title: Elevated temperature drives the biosynthesis of novel acylated glucosinolates in Arabidopsis thaliana seeds

doi: 10.64898/2026.06.03.729804

Figure Lengend Snippet: a) Log 2 ([elevated temperature/control] average total accumulation) of metabolic categories (n≥3) at six different seed developmental stages. b) Untargeted metabolomic data statistical analysis. c) Differentially accumulated metabolic features during seed development. d) Number of major metabolic categories (Flavonoids, Cinnamic acids and derivatives, and Glucosinolates) induced by elevated temperature at each seed developmental stage. e) Transcriptomic data statistical analysis. f) Differentially expressed genes during seed development. g) Percentages of genes coding for enzymes putatively involved in specialized metabolite modifications (Acyltransferases, Glycosyltransferases, Hydroxylases and Methyltransferases) induced, and repressed, at each seed developmental stage by elevated temperature.

Article Snippet: Untargeted metabolomic raw data (.mzXML) for both negative and positive ESI modes, and metadata have been deposited at the MassiVE data repository portal with the following identifiers: The transcriptomic RNA-Seq raw data (FASTQ) have been deposited at the National Center for Biotechnology Information (NCBI) Transcriptome Shotgun Assembly Sequence Database (TSA) with BioProject identification PRJNA1344327.

Techniques: Control, Metabolomic