Review



ferroptosis model  (TargetMol)


Bioz Verified Symbol TargetMol is a verified supplier
Bioz Manufacturer Symbol TargetMol manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 96

    Structured Review

    TargetMol ferroptosis model
    Mining of key genes for <t>ferroptosis</t> and verification in external databases. (A) The 5-set Venn diagram showing the comprehensive strategy among suppressor ferroptosis-associated genes (green circle), unclassified ferroptosis-associated genes (orange circle), marker ferroptosis-associated genes (blue circle), driver ferroptosis-associated genes (pink circle), and differentially expressed genes (DEGs) (purple circle). (B) ROC analysis for DUSP1 in the discovery dataset. (C) ROC analysis for PTGS2 in the discovery dataset. (D) ROC analysis for DUSP1 in the validation dataset. (E) ROC analysis for PTGS2 in the validation dataset. ROC, receiver operating characteristic.
    Ferroptosis Model, supplied by TargetMol, used in various techniques. Bioz Stars score: 96/100, based on 122 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/Ferroptosis+Compound+Library/pmc12354519-82-9-4
    Average 96 stars, based on 122 article reviews
    ferroptosis model - by Bioz Stars, 2026-11
    96/100 stars

    Images

    1) Product Images from "Exosomal circ_0093708 as a potential ferroptosis biomarker in cerebral ischemia–reperfusion injury"

    Article Title: Exosomal circ_0093708 as a potential ferroptosis biomarker in cerebral ischemia–reperfusion injury

    Journal: Frontiers in Neurology

    doi: 10.3389/fneur.2025.1633393

    Mining of key genes for ferroptosis and verification in external databases. (A) The 5-set Venn diagram showing the comprehensive strategy among suppressor ferroptosis-associated genes (green circle), unclassified ferroptosis-associated genes (orange circle), marker ferroptosis-associated genes (blue circle), driver ferroptosis-associated genes (pink circle), and differentially expressed genes (DEGs) (purple circle). (B) ROC analysis for DUSP1 in the discovery dataset. (C) ROC analysis for PTGS2 in the discovery dataset. (D) ROC analysis for DUSP1 in the validation dataset. (E) ROC analysis for PTGS2 in the validation dataset. ROC, receiver operating characteristic.
    Figure Legend Snippet: Mining of key genes for ferroptosis and verification in external databases. (A) The 5-set Venn diagram showing the comprehensive strategy among suppressor ferroptosis-associated genes (green circle), unclassified ferroptosis-associated genes (orange circle), marker ferroptosis-associated genes (blue circle), driver ferroptosis-associated genes (pink circle), and differentially expressed genes (DEGs) (purple circle). (B) ROC analysis for DUSP1 in the discovery dataset. (C) ROC analysis for PTGS2 in the discovery dataset. (D) ROC analysis for DUSP1 in the validation dataset. (E) ROC analysis for PTGS2 in the validation dataset. ROC, receiver operating characteristic.

    Techniques Used: Marker, Biomarker Discovery

    Inhibition of DUSP1 exacerbates ferroptosis in PC12 cells. (A) Cell viability after CIL56 treatment. (B) Intracellular MDA levels. (C) Effect of BCI on DUSP1 inhibition in the ferroptosis model. (D) Intracellular ROS levels (scale bar: 20 μm). (E) Protein expression of DUSP1, GPX4, and TFRC. (F) Quantification of GPX4 levels. (G) Quantification of TFRC levels. Data were analyzed by one-way ANOVA with Tukey’s post hoc test and presented as mean ± SD. Con, control.
    Figure Legend Snippet: Inhibition of DUSP1 exacerbates ferroptosis in PC12 cells. (A) Cell viability after CIL56 treatment. (B) Intracellular MDA levels. (C) Effect of BCI on DUSP1 inhibition in the ferroptosis model. (D) Intracellular ROS levels (scale bar: 20 μm). (E) Protein expression of DUSP1, GPX4, and TFRC. (F) Quantification of GPX4 levels. (G) Quantification of TFRC levels. Data were analyzed by one-way ANOVA with Tukey’s post hoc test and presented as mean ± SD. Con, control.

    Techniques Used: Inhibition, Expressing, Control

    Related Articles

    other:

    Article Title: Direct coupling and protective activation of DRP1 by the DNA-PKcs inhibitor KU-57788 synergizes with ferroptosis in anaplastic thyroid cancer cells.
    Article Snippet: 8505C and Hth-7 cells were treated with KU-57788 for 24 hours, then harvested and fixed with an electron microscope fixative (HaoKe Biotechnology Co. Ltd, China).

    Article Title: MXD4 enhances resistance to KRAS G12C-targeted therapy in lung adenocarcinoma by suppressing ACSL4-mediated ferroptosis.
    Article Snippet: A range of reagents was procured from various suppliers, including KRAS G12C inhibitors such as fulzerasib (#T73190, TargetMol, Boston, Massachusetts, USA), garsorasib (#E1578, Selleck, Shanghai, China), sotorasib (#T8684, TargetMol), and adagrasib (#T8369, TargetMol); Mitogen-activated protein kinase (MAPK) pathway inhibitors including trametinib (#T2125, TargetMol) and SCH772984 (#T6066, AR TIC LE IN PR ES S TargetMol); the pan-RAS inhibitor RMC-7977 (#T81263, TargetMol); ferroptosis inducers, including RSL3 (#R302648, Aladdin, Shanghai, China) and Imidazole ketone erastin (IKE) (#T5523, TargetMol); as well as other inhibitors of cell death such as ferrostatin-1 (fer-1) (#T6500, TargetMol), deferoxamine (DFO) (#T1637, TargetMol), Z-VAD-FMK (Z-VAD) (#T7020, TargetMol), and necrosulfonamide (necro) (#T6904, TargetMol).

    Cell Culture:

    Article Title: Psychological stress drives aging-like hematopoietic stem cell dysfunction through a brain-gut-bone marrow axis.
    Article Snippet: Article Psychological stress drives aging-like hematopoietic stem cell dysfunction through a brain-gut-bone marrow axis

    Cell Viability Assay:

    Article Title: Inhibition of the lipocalin-2-phosphatidylserine axis restores natural killer cell immune surveillance.
    Article Snippet: Ferroptosis induction and cell viability assay Cell viability was assessed using a Cell Counting Kit-8 (CCK8, TargetMol, C0005). .. Ferroptosis induction and cell viability assay Cell viability was assessed using a Cell Counting Kit-8 (CCK8, TargetMol, C0005). .. Briefly, 10,000 tumor cells were seeded in 96-well plates and allowed to adhere for 24 h. Ferroptosis agonists, RSL3 (1 μM, Selleck, S8155) and Erastin (5 μM, Selleck, S7242), Semapimod, the ferroptosis inhibitor Ferrostatin-1 (10 μM, Selleck, S7243), and a co-treatment group were then added.

    CCK-8 Assay:

    Article Title: Inhibition of the lipocalin-2-phosphatidylserine axis restores natural killer cell immune surveillance.
    Article Snippet: Ferroptosis induction and cell viability assay Cell viability was assessed using a Cell Counting Kit-8 (CCK8, TargetMol, C0005). .. Ferroptosis induction and cell viability assay Cell viability was assessed using a Cell Counting Kit-8 (CCK8, TargetMol, C0005). .. Briefly, 10,000 tumor cells were seeded in 96-well plates and allowed to adhere for 24 h. Ferroptosis agonists, RSL3 (1 μM, Selleck, S8155) and Erastin (5 μM, Selleck, S7242), Semapimod, the ferroptosis inhibitor Ferrostatin-1 (10 μM, Selleck, S7243), and a co-treatment group were then added.



    Similar Products

    94
    Danaher Inc flipr penta
    Flipr Penta, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/FLIPR+Penta+High-Throughput+Cellular+Screening+System/pm42906386-232-42-52
    Average 94 stars, based on 1 article reviews
    flipr penta - by Bioz Stars, 2026-11
    94/100 stars
      Buy from Supplier

    95
    TargetMol fda drug library high throughput screen
    Fda Drug Library High Throughput Screen, supplied by TargetMol, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/FDA-Approved+Drug+Library/pm42880285-1948-0-11
    Average 95 stars, based on 1 article reviews
    fda drug library high throughput screen - by Bioz Stars, 2026-11
    95/100 stars
      Buy from Supplier

    94
    Danaher Inc flipr system
    Flipr System, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/FLIPR+Penta+High-Throughput+Cellular+Screening+System/pm42869148-182-3-5
    Average 94 stars, based on 1 article reviews
    flipr system - by Bioz Stars, 2026-11
    94/100 stars
      Buy from Supplier

    94
    Danaher Inc flipr high throughput calcium imaging system
    Flipr High Throughput Calcium Imaging System, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/FLIPR+Penta+High-Throughput+Cellular+Screening+System/pm42810298-152-14-19
    Average 94 stars, based on 1 article reviews
    flipr high throughput calcium imaging system - by Bioz Stars, 2026-11
    94/100 stars
      Buy from Supplier

    94
    Danaher Inc flipr penta system
    Flipr Penta System, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/FLIPR+Penta+High-Throughput+Cellular+Screening+System/pmc13649475-50-5-8
    Average 94 stars, based on 1 article reviews
    flipr penta system - by Bioz Stars, 2026-11
    94/100 stars
      Buy from Supplier

    86
    Omics Data Automation high throughput screening
    High Throughput Screening, supplied by Omics Data Automation, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/high+screening+throughput/pm42277912-503-8-1
    Average 86 stars, based on 1 article reviews
    high throughput screening - by Bioz Stars, 2026-11
    86/100 stars
      Buy from Supplier

    95
    Twist Bioscience throughput screening libraries
    Throughput Screening Libraries, supplied by Twist Bioscience, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/Screening/pm42168701-316-1-11
    Average 95 stars, based on 1 article reviews
    throughput screening libraries - by Bioz Stars, 2026-11
    95/100 stars
      Buy from Supplier

    95
    Twist Bioscience throughput screening
    Throughput Screening, supplied by Twist Bioscience, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/Screening/bio_rxiv__64898__2026__04__27__720408-254-1-44
    Average 95 stars, based on 1 article reviews
    throughput screening - by Bioz Stars, 2026-11
    95/100 stars
      Buy from Supplier

    96
    Revvity opera phenix plus high throughput microplate confocal imager
    Opera Phenix Plus High Throughput Microplate Confocal Imager, supplied by Revvity, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/throughput+screening/Opera+Phenix+Plus+high-content+screening+system/pm42033519-108-9-16
    Average 96 stars, based on 1 article reviews
    opera phenix plus high throughput microplate confocal imager - by Bioz Stars, 2026-11
    96/100 stars
      Buy from Supplier

    Image Search Results