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Cambridge Isotope Laboratories 2,3,7,8-tetrachlorodibenzofuran tcdf
2,3,7,8 Tetrachlorodibenzofuran Tcdf, supplied by Cambridge Isotope Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tcdf/2+3+7+8+tetrachlorodibenzo+p+dioxin/pmc11516111-183-9-12
Average 90 stars, based on 1 article reviews
2,3,7,8-tetrachlorodibenzofuran tcdf - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation
Article Snippet: Main reagents used in this manuscript were as follows; 2,3,7,8‐Tetrachlorodibenzofuran (TCDF, #EF‐903‐C, Cambridge Isotope Laboratories), myriocin (from Mycelia sterilia, #M1177, SIGMA), S1P bioactive lipid (#73 914, SIGMA), SPHK2 inhibitor ABC294640 (C 23 H 25 ClN 2 O, #B‐0025, Echelon Biosciences Inc.).

Article Title: Postnatal administration of S-adenosylmethionine restores developmental AHR activation-induced deficits in CD8+ T cell function during influenza A virus infection.
Article Snippet: Developmental exposures can influence life-long health; yet, counteracting negative consequences is challenging due to poor understanding of cellular mechanisms.. The aryl hydrocarbon receptor (AHR) binds many small molecules, including numerous pollutants.. Developmental exposure to the signature environmental AHR ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) significantly dampens adaptive immune responses to influenza A virus in adult offspring.

Article Title: Juvenile exposure to low-level 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) alters behavior and longitudinal morphometrics in zebrafish and F<sub>1</sub> offspring
Article Snippet: Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an environmental endocrine disruptor and model AhR agonist, is linked to skeletal abnormalities, cardiac edema, stunted growth rate, altered metabolism, and neurobehavioral deficits.. We have previously reported transgenerational reproductive outcomes of developmental TCDD exposure in adult zebrafish (Danio rerio), an NIH-validated model for developmental and generational toxicology.. Using the same paradigm of sublethal TCDD exposure (50 pg/ml) at both 3 and 7 weeks post fertilization (wpf), we investigated several novel endpoints, including longitudinal morphometrics and anxiety-linked behavior, in fish exposed as juveniles.

Sterility:

Article Title: Enhancer RNA transcription pinpoints functional genetic variants linked to asthma
Article Snippet: Recombinant Human TNF-alpha Protein (TNF) purchased from R&D Systems was diluted in sterile 1X Dulbecco’s phosphate buffered saline (DPBS) containing 0.1% bovine serum albumin (BSA) and used at a final concentration of 20 ng/ml. .. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) obtained from Cambridge Isotope Laboratories was diluted in sterile DMSO (vehicle) and used at a final concentration of 10 nM. ..

Concentration Assay:

Article Title: Enhancer RNA transcription pinpoints functional genetic variants linked to asthma
Article Snippet: Recombinant Human TNF-alpha Protein (TNF) purchased from R&D Systems was diluted in sterile 1X Dulbecco’s phosphate buffered saline (DPBS) containing 0.1% bovine serum albumin (BSA) and used at a final concentration of 20 ng/ml. .. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) obtained from Cambridge Isotope Laboratories was diluted in sterile DMSO (vehicle) and used at a final concentration of 10 nM. ..



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