Review



sta 21  (Selleck Chemicals)


Bioz Verified Symbol Selleck Chemicals is a verified supplier
Bioz Manufacturer Symbol Selleck Chemicals manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 91

    Structured Review

    Selleck Chemicals sta 21
    Sta 21, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/Ochromycinone/pmc09989825-24-0-2
    Average 91 stars, based on 2 article reviews
    sta 21 - by Bioz Stars, 2026-10
    91/100 stars

    Images

    Related Articles

    other:

    Article Title: Cationic amphiphilic antihistamines inhibit STAT3 via Ca 2+ -dependent lysosomal H + efflux
    Article Snippet: STA-21 , Selleckchem , Cat# S7951.

    Recombinant:

    Article Title: Cationic amphiphilic antihistamines inhibit STAT3 via Ca 2+ -dependent lysosomal H + efflux
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-STAT3 Cell Signaling Technology Cat# 4904, RRID:AB_331269 HRP-anti-a-Tubulin Abcam Cat# ab40742, RRID:AB_880625 Rabbit anti-CCND1 Millipore Cat# 06–137, RRID:AB_2070695 Rabbit anti-P-STAT3(S727) Abcam Cat# ab86430, RRID:AB_10713219 Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-Galectin 1 Abcam Cat# ab25138, RRID:AB_2136615 Rabbit anti-BAX Cell Signaling Technology Cat# 2772, RRID:AB_10695870 Donkey anti-rabbit IgG, Alexa Fluor 594 Thermo Fisher Scientific Cat# A-21207, RRID:AB_141637 Donkey anti-rabbit IgG, Alexa Fluor 488 Thermo Fisher Scientific Cat# A-21206, RRID:AB_2535792 Anti-rabbit IgG from goat Vector Laboratories Cat# PI-1000, RRID:AB_2336198 Chemicals, peptides, and recombinant proteins Terfenadine Sigma Aldrich Cat# T9652 Niclosamide Sigma Aldrich Cat# N3510 Forskolin Sigma Aldrich Cat# 93049 Penfluridol Sigma Aldrich Cat# P3371 Astemizole Sigma Aldrich Cat# A2861 EIPA Sigma Aldrich Cat# A3085 Ebastine Cayman Chemical Cat# T9652 WP1066 Merk Cat# N3510 STA-21 Selleckchem Cat# S7951 Stattic Abcam Cat# Ab120952 Hoechst 33,342 Sigma Aldrich Cat# B2261 Propidium iodide solution Sigma Aldrich Cat# P4864 Dextran, Fluorescein, 70,000 MW, Anionic Thermo Fisher Scientific Cat# D-1823 Dextran, Tetramethylrhodamine, 70,000 MW Thermo Fisher Scientific Cat# D-1818 BCECF-AM Thermo Fisher Scientific Cat# B1170 cOmplete Protease inhibitor Cocktail Merk Cat# 11697498001 Critical commercial assays TurboFectin 8.0 Origene Cat# TF81001 Lipofectamine 3000 Thermo Fisher Scientific Cat# L3000008 Lipofectamine RNAmax Thermo Fisher Scientific Cat# 13778075 NE-PERTM Nuclear Extraction Kit Thermo Fisher Scientific Cat# 78833 Quant-XTM One-Step qRT-PCR SYBR Kit Takara Bio Cat# 638317 Pierce Gaussia Luciferase Glow Assay Kit Thermo Fisher Scientific Cat# 16160 Fluo 4, AM Thermo Fisher Scientific Cat# F-14201 Venor GeM Classic PCR kit MB Minerva biolabs Cat# 11-1025G (Continued on next page) Cell Reports 42, 112137, February 28, 2023 15 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Cell lines HeLa cervix carcinoma cell ECACC Cat# 93021013, RRID:CVCL_0030 HeLa NC4, STAT3 KO1, STAT3 KO11 Liu et al.12 N/A PANC-1 pancreatic tumor cell Creative Bioarray CSC-C8212L A549 non-small cell lung carcinoma cell ATCC Cat# CCL-185, RRID:CVCL_0023 A549 triple cell Dmitry Malkov lab N/A MCF7 breast cancer cell, TNF-sensitive subclone S1 Jaattela et al.,62 N/A Experimental models: Organisms/strains BALB/c nude mouse Beijing Vital River Laboratory Animal Technology Co., Ltd N/A Oligonucleotides Primers for qPCR: See Table S1 This paper N/A Primers for cloning: See Table S1 This paper N/A siRNA targeting STAT3, P2RX4, ADCY1, TMEM165: See Table S1 This paper N/A Recombinant DNA pC1SypHer3S Addgene Cat# 108118 Flamindo2 Addgene Cat# 73938 pLentiCMVIE-IRES-BlastR Addgene Cat# 119863 Software and algorithms Fiji Schneider et al.63 ImageJ.net/Fiji GraphPad Prism 8.0 GraphPad Prism https://www.graphpad.com/scientific-software/prism/ Image Studio lite Li-COR https://www.licor.com/bio/image-studio-lite/ MetaXpress software Molecular Device https://www.moleculardevices.com/products/ cellular-imaging-systems/acquisition-andanalysis-software/metaxpress#gref Other MicroliteTM1 Luminescence Microtiter 96-well plate VWR Scientific Cat# 62403-124 pHrodo Green-AM Thermo Fisher Scientific Cat# P35373 Live Cell Imaging Solution Thermo Fisher Scientific Cat# A14291DJ Article ll OPEN ACCESS

    Protease Inhibitor:

    Article Title: Cationic amphiphilic antihistamines inhibit STAT3 via Ca 2+ -dependent lysosomal H + efflux
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-STAT3 Cell Signaling Technology Cat# 4904, RRID:AB_331269 HRP-anti-a-Tubulin Abcam Cat# ab40742, RRID:AB_880625 Rabbit anti-CCND1 Millipore Cat# 06–137, RRID:AB_2070695 Rabbit anti-P-STAT3(S727) Abcam Cat# ab86430, RRID:AB_10713219 Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-Galectin 1 Abcam Cat# ab25138, RRID:AB_2136615 Rabbit anti-BAX Cell Signaling Technology Cat# 2772, RRID:AB_10695870 Donkey anti-rabbit IgG, Alexa Fluor 594 Thermo Fisher Scientific Cat# A-21207, RRID:AB_141637 Donkey anti-rabbit IgG, Alexa Fluor 488 Thermo Fisher Scientific Cat# A-21206, RRID:AB_2535792 Anti-rabbit IgG from goat Vector Laboratories Cat# PI-1000, RRID:AB_2336198 Chemicals, peptides, and recombinant proteins Terfenadine Sigma Aldrich Cat# T9652 Niclosamide Sigma Aldrich Cat# N3510 Forskolin Sigma Aldrich Cat# 93049 Penfluridol Sigma Aldrich Cat# P3371 Astemizole Sigma Aldrich Cat# A2861 EIPA Sigma Aldrich Cat# A3085 Ebastine Cayman Chemical Cat# T9652 WP1066 Merk Cat# N3510 STA-21 Selleckchem Cat# S7951 Stattic Abcam Cat# Ab120952 Hoechst 33,342 Sigma Aldrich Cat# B2261 Propidium iodide solution Sigma Aldrich Cat# P4864 Dextran, Fluorescein, 70,000 MW, Anionic Thermo Fisher Scientific Cat# D-1823 Dextran, Tetramethylrhodamine, 70,000 MW Thermo Fisher Scientific Cat# D-1818 BCECF-AM Thermo Fisher Scientific Cat# B1170 cOmplete Protease inhibitor Cocktail Merk Cat# 11697498001 Critical commercial assays TurboFectin 8.0 Origene Cat# TF81001 Lipofectamine 3000 Thermo Fisher Scientific Cat# L3000008 Lipofectamine RNAmax Thermo Fisher Scientific Cat# 13778075 NE-PERTM Nuclear Extraction Kit Thermo Fisher Scientific Cat# 78833 Quant-XTM One-Step qRT-PCR SYBR Kit Takara Bio Cat# 638317 Pierce Gaussia Luciferase Glow Assay Kit Thermo Fisher Scientific Cat# 16160 Fluo 4, AM Thermo Fisher Scientific Cat# F-14201 Venor GeM Classic PCR kit MB Minerva biolabs Cat# 11-1025G (Continued on next page) Cell Reports 42, 112137, February 28, 2023 15 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Cell lines HeLa cervix carcinoma cell ECACC Cat# 93021013, RRID:CVCL_0030 HeLa NC4, STAT3 KO1, STAT3 KO11 Liu et al.12 N/A PANC-1 pancreatic tumor cell Creative Bioarray CSC-C8212L A549 non-small cell lung carcinoma cell ATCC Cat# CCL-185, RRID:CVCL_0023 A549 triple cell Dmitry Malkov lab N/A MCF7 breast cancer cell, TNF-sensitive subclone S1 Jaattela et al.,62 N/A Experimental models: Organisms/strains BALB/c nude mouse Beijing Vital River Laboratory Animal Technology Co., Ltd N/A Oligonucleotides Primers for qPCR: See Table S1 This paper N/A Primers for cloning: See Table S1 This paper N/A siRNA targeting STAT3, P2RX4, ADCY1, TMEM165: See Table S1 This paper N/A Recombinant DNA pC1SypHer3S Addgene Cat# 108118 Flamindo2 Addgene Cat# 73938 pLentiCMVIE-IRES-BlastR Addgene Cat# 119863 Software and algorithms Fiji Schneider et al.63 ImageJ.net/Fiji GraphPad Prism 8.0 GraphPad Prism https://www.graphpad.com/scientific-software/prism/ Image Studio lite Li-COR https://www.licor.com/bio/image-studio-lite/ MetaXpress software Molecular Device https://www.moleculardevices.com/products/ cellular-imaging-systems/acquisition-andanalysis-software/metaxpress#gref Other MicroliteTM1 Luminescence Microtiter 96-well plate VWR Scientific Cat# 62403-124 pHrodo Green-AM Thermo Fisher Scientific Cat# P35373 Live Cell Imaging Solution Thermo Fisher Scientific Cat# A14291DJ Article ll OPEN ACCESS

    Extraction:

    Article Title: Cationic amphiphilic antihistamines inhibit STAT3 via Ca 2+ -dependent lysosomal H + efflux
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-STAT3 Cell Signaling Technology Cat# 4904, RRID:AB_331269 HRP-anti-a-Tubulin Abcam Cat# ab40742, RRID:AB_880625 Rabbit anti-CCND1 Millipore Cat# 06–137, RRID:AB_2070695 Rabbit anti-P-STAT3(S727) Abcam Cat# ab86430, RRID:AB_10713219 Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-Galectin 1 Abcam Cat# ab25138, RRID:AB_2136615 Rabbit anti-BAX Cell Signaling Technology Cat# 2772, RRID:AB_10695870 Donkey anti-rabbit IgG, Alexa Fluor 594 Thermo Fisher Scientific Cat# A-21207, RRID:AB_141637 Donkey anti-rabbit IgG, Alexa Fluor 488 Thermo Fisher Scientific Cat# A-21206, RRID:AB_2535792 Anti-rabbit IgG from goat Vector Laboratories Cat# PI-1000, RRID:AB_2336198 Chemicals, peptides, and recombinant proteins Terfenadine Sigma Aldrich Cat# T9652 Niclosamide Sigma Aldrich Cat# N3510 Forskolin Sigma Aldrich Cat# 93049 Penfluridol Sigma Aldrich Cat# P3371 Astemizole Sigma Aldrich Cat# A2861 EIPA Sigma Aldrich Cat# A3085 Ebastine Cayman Chemical Cat# T9652 WP1066 Merk Cat# N3510 STA-21 Selleckchem Cat# S7951 Stattic Abcam Cat# Ab120952 Hoechst 33,342 Sigma Aldrich Cat# B2261 Propidium iodide solution Sigma Aldrich Cat# P4864 Dextran, Fluorescein, 70,000 MW, Anionic Thermo Fisher Scientific Cat# D-1823 Dextran, Tetramethylrhodamine, 70,000 MW Thermo Fisher Scientific Cat# D-1818 BCECF-AM Thermo Fisher Scientific Cat# B1170 cOmplete Protease inhibitor Cocktail Merk Cat# 11697498001 Critical commercial assays TurboFectin 8.0 Origene Cat# TF81001 Lipofectamine 3000 Thermo Fisher Scientific Cat# L3000008 Lipofectamine RNAmax Thermo Fisher Scientific Cat# 13778075 NE-PERTM Nuclear Extraction Kit Thermo Fisher Scientific Cat# 78833 Quant-XTM One-Step qRT-PCR SYBR Kit Takara Bio Cat# 638317 Pierce Gaussia Luciferase Glow Assay Kit Thermo Fisher Scientific Cat# 16160 Fluo 4, AM Thermo Fisher Scientific Cat# F-14201 Venor GeM Classic PCR kit MB Minerva biolabs Cat# 11-1025G (Continued on next page) Cell Reports 42, 112137, February 28, 2023 15 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Cell lines HeLa cervix carcinoma cell ECACC Cat# 93021013, RRID:CVCL_0030 HeLa NC4, STAT3 KO1, STAT3 KO11 Liu et al.12 N/A PANC-1 pancreatic tumor cell Creative Bioarray CSC-C8212L A549 non-small cell lung carcinoma cell ATCC Cat# CCL-185, RRID:CVCL_0023 A549 triple cell Dmitry Malkov lab N/A MCF7 breast cancer cell, TNF-sensitive subclone S1 Jaattela et al.,62 N/A Experimental models: Organisms/strains BALB/c nude mouse Beijing Vital River Laboratory Animal Technology Co., Ltd N/A Oligonucleotides Primers for qPCR: See Table S1 This paper N/A Primers for cloning: See Table S1 This paper N/A siRNA targeting STAT3, P2RX4, ADCY1, TMEM165: See Table S1 This paper N/A Recombinant DNA pC1SypHer3S Addgene Cat# 108118 Flamindo2 Addgene Cat# 73938 pLentiCMVIE-IRES-BlastR Addgene Cat# 119863 Software and algorithms Fiji Schneider et al.63 ImageJ.net/Fiji GraphPad Prism 8.0 GraphPad Prism https://www.graphpad.com/scientific-software/prism/ Image Studio lite Li-COR https://www.licor.com/bio/image-studio-lite/ MetaXpress software Molecular Device https://www.moleculardevices.com/products/ cellular-imaging-systems/acquisition-andanalysis-software/metaxpress#gref Other MicroliteTM1 Luminescence Microtiter 96-well plate VWR Scientific Cat# 62403-124 pHrodo Green-AM Thermo Fisher Scientific Cat# P35373 Live Cell Imaging Solution Thermo Fisher Scientific Cat# A14291DJ Article ll OPEN ACCESS

    Quantitative RT-PCR:

    Article Title: Cationic amphiphilic antihistamines inhibit STAT3 via Ca 2+ -dependent lysosomal H + efflux
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-STAT3 Cell Signaling Technology Cat# 4904, RRID:AB_331269 HRP-anti-a-Tubulin Abcam Cat# ab40742, RRID:AB_880625 Rabbit anti-CCND1 Millipore Cat# 06–137, RRID:AB_2070695 Rabbit anti-P-STAT3(S727) Abcam Cat# ab86430, RRID:AB_10713219 Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-Galectin 1 Abcam Cat# ab25138, RRID:AB_2136615 Rabbit anti-BAX Cell Signaling Technology Cat# 2772, RRID:AB_10695870 Donkey anti-rabbit IgG, Alexa Fluor 594 Thermo Fisher Scientific Cat# A-21207, RRID:AB_141637 Donkey anti-rabbit IgG, Alexa Fluor 488 Thermo Fisher Scientific Cat# A-21206, RRID:AB_2535792 Anti-rabbit IgG from goat Vector Laboratories Cat# PI-1000, RRID:AB_2336198 Chemicals, peptides, and recombinant proteins Terfenadine Sigma Aldrich Cat# T9652 Niclosamide Sigma Aldrich Cat# N3510 Forskolin Sigma Aldrich Cat# 93049 Penfluridol Sigma Aldrich Cat# P3371 Astemizole Sigma Aldrich Cat# A2861 EIPA Sigma Aldrich Cat# A3085 Ebastine Cayman Chemical Cat# T9652 WP1066 Merk Cat# N3510 STA-21 Selleckchem Cat# S7951 Stattic Abcam Cat# Ab120952 Hoechst 33,342 Sigma Aldrich Cat# B2261 Propidium iodide solution Sigma Aldrich Cat# P4864 Dextran, Fluorescein, 70,000 MW, Anionic Thermo Fisher Scientific Cat# D-1823 Dextran, Tetramethylrhodamine, 70,000 MW Thermo Fisher Scientific Cat# D-1818 BCECF-AM Thermo Fisher Scientific Cat# B1170 cOmplete Protease inhibitor Cocktail Merk Cat# 11697498001 Critical commercial assays TurboFectin 8.0 Origene Cat# TF81001 Lipofectamine 3000 Thermo Fisher Scientific Cat# L3000008 Lipofectamine RNAmax Thermo Fisher Scientific Cat# 13778075 NE-PERTM Nuclear Extraction Kit Thermo Fisher Scientific Cat# 78833 Quant-XTM One-Step qRT-PCR SYBR Kit Takara Bio Cat# 638317 Pierce Gaussia Luciferase Glow Assay Kit Thermo Fisher Scientific Cat# 16160 Fluo 4, AM Thermo Fisher Scientific Cat# F-14201 Venor GeM Classic PCR kit MB Minerva biolabs Cat# 11-1025G (Continued on next page) Cell Reports 42, 112137, February 28, 2023 15 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Cell lines HeLa cervix carcinoma cell ECACC Cat# 93021013, RRID:CVCL_0030 HeLa NC4, STAT3 KO1, STAT3 KO11 Liu et al.12 N/A PANC-1 pancreatic tumor cell Creative Bioarray CSC-C8212L A549 non-small cell lung carcinoma cell ATCC Cat# CCL-185, RRID:CVCL_0023 A549 triple cell Dmitry Malkov lab N/A MCF7 breast cancer cell, TNF-sensitive subclone S1 Jaattela et al.,62 N/A Experimental models: Organisms/strains BALB/c nude mouse Beijing Vital River Laboratory Animal Technology Co., Ltd N/A Oligonucleotides Primers for qPCR: See Table S1 This paper N/A Primers for cloning: See Table S1 This paper N/A siRNA targeting STAT3, P2RX4, ADCY1, TMEM165: See Table S1 This paper N/A Recombinant DNA pC1SypHer3S Addgene Cat# 108118 Flamindo2 Addgene Cat# 73938 pLentiCMVIE-IRES-BlastR Addgene Cat# 119863 Software and algorithms Fiji Schneider et al.63 ImageJ.net/Fiji GraphPad Prism 8.0 GraphPad Prism https://www.graphpad.com/scientific-software/prism/ Image Studio lite Li-COR https://www.licor.com/bio/image-studio-lite/ MetaXpress software Molecular Device https://www.moleculardevices.com/products/ cellular-imaging-systems/acquisition-andanalysis-software/metaxpress#gref Other MicroliteTM1 Luminescence Microtiter 96-well plate VWR Scientific Cat# 62403-124 pHrodo Green-AM Thermo Fisher Scientific Cat# P35373 Live Cell Imaging Solution Thermo Fisher Scientific Cat# A14291DJ Article ll OPEN ACCESS

    Luciferase:

    Article Title: Cationic amphiphilic antihistamines inhibit STAT3 via Ca 2+ -dependent lysosomal H + efflux
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-STAT3 Cell Signaling Technology Cat# 4904, RRID:AB_331269 HRP-anti-a-Tubulin Abcam Cat# ab40742, RRID:AB_880625 Rabbit anti-CCND1 Millipore Cat# 06–137, RRID:AB_2070695 Rabbit anti-P-STAT3(S727) Abcam Cat# ab86430, RRID:AB_10713219 Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-Galectin 1 Abcam Cat# ab25138, RRID:AB_2136615 Rabbit anti-BAX Cell Signaling Technology Cat# 2772, RRID:AB_10695870 Donkey anti-rabbit IgG, Alexa Fluor 594 Thermo Fisher Scientific Cat# A-21207, RRID:AB_141637 Donkey anti-rabbit IgG, Alexa Fluor 488 Thermo Fisher Scientific Cat# A-21206, RRID:AB_2535792 Anti-rabbit IgG from goat Vector Laboratories Cat# PI-1000, RRID:AB_2336198 Chemicals, peptides, and recombinant proteins Terfenadine Sigma Aldrich Cat# T9652 Niclosamide Sigma Aldrich Cat# N3510 Forskolin Sigma Aldrich Cat# 93049 Penfluridol Sigma Aldrich Cat# P3371 Astemizole Sigma Aldrich Cat# A2861 EIPA Sigma Aldrich Cat# A3085 Ebastine Cayman Chemical Cat# T9652 WP1066 Merk Cat# N3510 STA-21 Selleckchem Cat# S7951 Stattic Abcam Cat# Ab120952 Hoechst 33,342 Sigma Aldrich Cat# B2261 Propidium iodide solution Sigma Aldrich Cat# P4864 Dextran, Fluorescein, 70,000 MW, Anionic Thermo Fisher Scientific Cat# D-1823 Dextran, Tetramethylrhodamine, 70,000 MW Thermo Fisher Scientific Cat# D-1818 BCECF-AM Thermo Fisher Scientific Cat# B1170 cOmplete Protease inhibitor Cocktail Merk Cat# 11697498001 Critical commercial assays TurboFectin 8.0 Origene Cat# TF81001 Lipofectamine 3000 Thermo Fisher Scientific Cat# L3000008 Lipofectamine RNAmax Thermo Fisher Scientific Cat# 13778075 NE-PERTM Nuclear Extraction Kit Thermo Fisher Scientific Cat# 78833 Quant-XTM One-Step qRT-PCR SYBR Kit Takara Bio Cat# 638317 Pierce Gaussia Luciferase Glow Assay Kit Thermo Fisher Scientific Cat# 16160 Fluo 4, AM Thermo Fisher Scientific Cat# F-14201 Venor GeM Classic PCR kit MB Minerva biolabs Cat# 11-1025G (Continued on next page) Cell Reports 42, 112137, February 28, 2023 15 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Cell lines HeLa cervix carcinoma cell ECACC Cat# 93021013, RRID:CVCL_0030 HeLa NC4, STAT3 KO1, STAT3 KO11 Liu et al.12 N/A PANC-1 pancreatic tumor cell Creative Bioarray CSC-C8212L A549 non-small cell lung carcinoma cell ATCC Cat# CCL-185, RRID:CVCL_0023 A549 triple cell Dmitry Malkov lab N/A MCF7 breast cancer cell, TNF-sensitive subclone S1 Jaattela et al.,62 N/A Experimental models: Organisms/strains BALB/c nude mouse Beijing Vital River Laboratory Animal Technology Co., Ltd N/A Oligonucleotides Primers for qPCR: See Table S1 This paper N/A Primers for cloning: See Table S1 This paper N/A siRNA targeting STAT3, P2RX4, ADCY1, TMEM165: See Table S1 This paper N/A Recombinant DNA pC1SypHer3S Addgene Cat# 108118 Flamindo2 Addgene Cat# 73938 pLentiCMVIE-IRES-BlastR Addgene Cat# 119863 Software and algorithms Fiji Schneider et al.63 ImageJ.net/Fiji GraphPad Prism 8.0 GraphPad Prism https://www.graphpad.com/scientific-software/prism/ Image Studio lite Li-COR https://www.licor.com/bio/image-studio-lite/ MetaXpress software Molecular Device https://www.moleculardevices.com/products/ cellular-imaging-systems/acquisition-andanalysis-software/metaxpress#gref Other MicroliteTM1 Luminescence Microtiter 96-well plate VWR Scientific Cat# 62403-124 pHrodo Green-AM Thermo Fisher Scientific Cat# P35373 Live Cell Imaging Solution Thermo Fisher Scientific Cat# A14291DJ Article ll OPEN ACCESS

    Polymerase Chain Reaction:

    Article Title: Cationic amphiphilic antihistamines inhibit STAT3 via Ca 2+ -dependent lysosomal H + efflux
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-STAT3 Cell Signaling Technology Cat# 4904, RRID:AB_331269 HRP-anti-a-Tubulin Abcam Cat# ab40742, RRID:AB_880625 Rabbit anti-CCND1 Millipore Cat# 06–137, RRID:AB_2070695 Rabbit anti-P-STAT3(S727) Abcam Cat# ab86430, RRID:AB_10713219 Rabbit anti-P-STAT3(Y705) Cell Signaling Technology Cat# 9145, RRID:AB_2491009 Rabbit anti-Galectin 1 Abcam Cat# ab25138, RRID:AB_2136615 Rabbit anti-BAX Cell Signaling Technology Cat# 2772, RRID:AB_10695870 Donkey anti-rabbit IgG, Alexa Fluor 594 Thermo Fisher Scientific Cat# A-21207, RRID:AB_141637 Donkey anti-rabbit IgG, Alexa Fluor 488 Thermo Fisher Scientific Cat# A-21206, RRID:AB_2535792 Anti-rabbit IgG from goat Vector Laboratories Cat# PI-1000, RRID:AB_2336198 Chemicals, peptides, and recombinant proteins Terfenadine Sigma Aldrich Cat# T9652 Niclosamide Sigma Aldrich Cat# N3510 Forskolin Sigma Aldrich Cat# 93049 Penfluridol Sigma Aldrich Cat# P3371 Astemizole Sigma Aldrich Cat# A2861 EIPA Sigma Aldrich Cat# A3085 Ebastine Cayman Chemical Cat# T9652 WP1066 Merk Cat# N3510 STA-21 Selleckchem Cat# S7951 Stattic Abcam Cat# Ab120952 Hoechst 33,342 Sigma Aldrich Cat# B2261 Propidium iodide solution Sigma Aldrich Cat# P4864 Dextran, Fluorescein, 70,000 MW, Anionic Thermo Fisher Scientific Cat# D-1823 Dextran, Tetramethylrhodamine, 70,000 MW Thermo Fisher Scientific Cat# D-1818 BCECF-AM Thermo Fisher Scientific Cat# B1170 cOmplete Protease inhibitor Cocktail Merk Cat# 11697498001 Critical commercial assays TurboFectin 8.0 Origene Cat# TF81001 Lipofectamine 3000 Thermo Fisher Scientific Cat# L3000008 Lipofectamine RNAmax Thermo Fisher Scientific Cat# 13778075 NE-PERTM Nuclear Extraction Kit Thermo Fisher Scientific Cat# 78833 Quant-XTM One-Step qRT-PCR SYBR Kit Takara Bio Cat# 638317 Pierce Gaussia Luciferase Glow Assay Kit Thermo Fisher Scientific Cat# 16160 Fluo 4, AM Thermo Fisher Scientific Cat# F-14201 Venor GeM Classic PCR kit MB Minerva biolabs Cat# 11-1025G (Continued on next page) Cell Reports 42, 112137, February 28, 2023 15 .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Cell lines HeLa cervix carcinoma cell ECACC Cat# 93021013, RRID:CVCL_0030 HeLa NC4, STAT3 KO1, STAT3 KO11 Liu et al.12 N/A PANC-1 pancreatic tumor cell Creative Bioarray CSC-C8212L A549 non-small cell lung carcinoma cell ATCC Cat# CCL-185, RRID:CVCL_0023 A549 triple cell Dmitry Malkov lab N/A MCF7 breast cancer cell, TNF-sensitive subclone S1 Jaattela et al.,62 N/A Experimental models: Organisms/strains BALB/c nude mouse Beijing Vital River Laboratory Animal Technology Co., Ltd N/A Oligonucleotides Primers for qPCR: See Table S1 This paper N/A Primers for cloning: See Table S1 This paper N/A siRNA targeting STAT3, P2RX4, ADCY1, TMEM165: See Table S1 This paper N/A Recombinant DNA pC1SypHer3S Addgene Cat# 108118 Flamindo2 Addgene Cat# 73938 pLentiCMVIE-IRES-BlastR Addgene Cat# 119863 Software and algorithms Fiji Schneider et al.63 ImageJ.net/Fiji GraphPad Prism 8.0 GraphPad Prism https://www.graphpad.com/scientific-software/prism/ Image Studio lite Li-COR https://www.licor.com/bio/image-studio-lite/ MetaXpress software Molecular Device https://www.moleculardevices.com/products/ cellular-imaging-systems/acquisition-andanalysis-software/metaxpress#gref Other MicroliteTM1 Luminescence Microtiter 96-well plate VWR Scientific Cat# 62403-124 pHrodo Green-AM Thermo Fisher Scientific Cat# P35373 Live Cell Imaging Solution Thermo Fisher Scientific Cat# A14291DJ Article ll OPEN ACCESS



    Similar Products

    96
    Santa Cruz Biotechnology stat3 inhibitor sta 21
    Stat3 Inhibitor Sta 21, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/Stat3/pm39487455-81-3-8
    Average 96 stars, based on 1 article reviews
    stat3 inhibitor sta 21 - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    92
    MedChemExpress ochromycinone rac sta
    Ochromycinone Rac Sta, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/Ochromycinone/pm39137465-101-30-32
    Average 92 stars, based on 1 article reviews
    ochromycinone rac sta - by Bioz Stars, 2026-10
    92/100 stars
      Buy from Supplier

    90
    Cayman Chemical sta-21 (ochromycinone)
    Sta 21 (Ochromycinone), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/sta+21++ochromycinone+/pm37802209-71-25-27
    Average 90 stars, based on 1 article reviews
    sta-21 (ochromycinone) - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    96
    Selleck Chemicals n3510 sta 21 selleckchem
    N3510 Sta 21 Selleckchem, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/Stattic/pm36807142-491-138-140
    Average 96 stars, based on 1 article reviews
    n3510 sta 21 selleckchem - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    93
    Santa Cruz Biotechnology sta 21
    Sta 21, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/STA-21/pm36933092-39-10-19
    Average 93 stars, based on 1 article reviews
    sta 21 - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    93
    Santa Cruz Biotechnology tnf α
    Tnf α, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/STA-21/pm36933092-39-8-19
    Average 93 stars, based on 1 article reviews
    tnf α - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    91
    Selleck Chemicals sta 21
    Sta 21, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/Ochromycinone/pmc09989825-24-0-2
    Average 91 stars, based on 1 article reviews
    sta 21 - by Bioz Stars, 2026-10
    91/100 stars
      Buy from Supplier

    92
    MedChemExpress 20mg body weight kg sta 21 mce hy 18061
    20mg Body Weight Kg Sta 21 Mce Hy 18061, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sta-21/Ochromycinone/pmc09951332__ADVS___10___2206335___s001-186-64-68
    Average 92 stars, based on 1 article reviews
    20mg body weight kg sta 21 mce hy 18061 - by Bioz Stars, 2026-10
    92/100 stars
      Buy from Supplier

    Image Search Results