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Molecular Dynamics Inc md simulation model
Md Simulation Model, supplied by Molecular Dynamics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/simulation/dynamics+molecular+simulations/pmc12749539-142-113-111
Average 86 stars, based on 1 article reviews
md simulation model - by Bioz Stars, 2026-09
86/100 stars

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Article Title: Selenium-Containing 1,4-Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple-Negative Breast Cancer Cells.
Article Snippet: Additionally, Molecular Dynamics Simulations (MD) were performed to investigate the molecular recognition of the ligands by topoisomerase II and evaluate their potential as enzyme inhibitors.

Article Title: Formulation of amorphous solid dispersion of clofazimine, an extremely water-insoluble basic drug, via hot-melt extrusion by applying acid-base supersolubilization principle.
Article Snippet: Clofazimine (CFZ) is an anti-leprosy and anti-tuberculosis drug listed on the World Health Organization's (WHO) Model List of Essential Medicines, but it is extremely water-insoluble and has major dissolution and bioavailability issues, and presumably for these reasons, its only commercially available formulation, Lamprene®, was withdrawn from the US market by its manufacturer.. The present investigation was undertaken to develop amorphous solid dispersions (ASDs) of CFZ using hot-melt extrusion (HME) to increase its dissolution rate.. The process was, however, challenging because CFZ has a high melting point of 224 °C, requiring high processing temperatures, at which the drug and the polymer used could degrade.

Functional Assay:

Article Title: Protein fibril-based delivery systems for bioactive substances: Structural design, functional regulation, and food applications.
Article Snippet: Protein fibrils (PFs) are β-sheet-rich supramolecular assemblies with high aspect ratios, tunable surface chemistry, and multiscale assembly behavior, making them promising food-grade carriers for bioactive compounds.. However, their delivery performance depends not simply on increasing fibril order or structural stability, but on balancing carrier robustness with molecular binding and release behavior.. This review examines the regulatory mechanisms of PFs and the roles of key structural features in governing their physicochemical and biological activities, treating PFs as foundational templates rather than direct raw materials.

Binding Assay:

Article Title: Protein fibril-based delivery systems for bioactive substances: Structural design, functional regulation, and food applications.
Article Snippet: Protein fibrils (PFs) are β-sheet-rich supramolecular assemblies with high aspect ratios, tunable surface chemistry, and multiscale assembly behavior, making them promising food-grade carriers for bioactive compounds.. However, their delivery performance depends not simply on increasing fibril order or structural stability, but on balancing carrier robustness with molecular binding and release behavior.. This review examines the regulatory mechanisms of PFs and the roles of key structural features in governing their physicochemical and biological activities, treating PFs as foundational templates rather than direct raw materials.



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