rt112 (DSMZ)
Structured Review

Rt112, supplied by DSMZ, used in various techniques. Bioz Stars score: 95/100, based on 157 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rt112/RT-112/pmc13046741-53-0-1
Average 95 stars, based on 157 article reviews
Images
1) Product Images from "Combining 5-ALA-PDT with berbamine as an in vitro multimodal therapy approach against bladder cancer cells"
Article Title: Combining 5-ALA-PDT with berbamine as an in vitro multimodal therapy approach against bladder cancer cells
Journal: Scientific Reports
doi: 10.1038/s41598-026-46092-x
Figure Legend Snippet: Effect of berbamine on 5-ALA-induced PpIX accumulation. RT112, RT112 LTT, RT112 CSC (top), and J82, J82 LTT, J82 CSC (bottom) were treated with 5-ALA (0–100 µg/ml) and berbamine (no, ½ IC 50 , IC 50 ). PpIX fluorescence intensity was normalized to cell viability and is shown as individual values with mean as a line. Asterisks indicate significance compared to the sample without berbamine (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).
Techniques Used: Fluorescence
Figure Legend Snippet: Cell viability of RT112, RT112 LTT and RT112 CSC following 5-ALA-PDT treatment with increasing irradiation doses and varying concentrations of 5-ALA and berbamine. Bars represent weighted means ± SD from three independent experiments ( n = 3 × 6; controls without irradiation n = 3 × 36). Asterisks indicate significance of unweighted means compared to the irradiated control sample without 5-ALA C1.1-C1.4 (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).
Techniques Used: Irradiation, Control
Figure Legend Snippet: Berbamine has cytotoxic effects in ROS generation, cell migration and apoptosis rate for cisplatin-resistant cell lines RT112 LTT and J82 LTT. Tert-butyl hydroperoxide (TBHP; 150 µM) served as positive control for determination of reactive oxygen species (ROS). Detailed data presentation for all cell lines are available in the supplementary section (Supplementary Figs. , and ). Data represent mean ± SD ( n = 3). Asterisks indicate significance relative to the control without berbamine (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).
Techniques Used: Migration, Positive Control, Control
Related Articles
Cell Culture:Article Title: Combining 5-ALA-PDT with berbamine as an in vitro multimodal therapy approach against bladder cancer cells. Article Snippet: .. Cell culture, general cell handling procedures, and Article Title: Preferential HER4 stimulation preserves neuregulin-induced improvement of myocardial function Article Snippet: All cancer cell lines were obtained from ATCC, except the human bladder tumor cell line RT-112 which was provided by DSMZ. .. Human NCI-N87 gastric carcinoma (CRL-5822, ATCC, Manassas, VA), T-47D breast carcinoma (HTB-133, ATCC), and RT-112 urinary Article Title: Multi‐omic profiling defines three distinct molecular subtypes of urothelial carcinoma with implications for precision therapy Article Snippet: UMUC3 cells (Sigma‐Aldrich) were cultured in DMEM‐low glucose medium (PAN‐Biotech). .. |