chamber med associates rat conditioned place preference box (Med Associates Inc)

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Med Associates Inc chamber med associates rat conditioned place preference box

a) Pavlovian <t>Conditioned</t> Approach (PCA) score across training days. Black line=control, grey line=ACRS. Positive values indicate bias toward the CS+ lever (sign tracking), negative values indicated bias toward food cup (goal tracking) *p<0.05, group × day interaction. b) Mean+SEM PCA Score on training days 7&8 show with black (control) or grey (ACRS) horizontal lines and error bars. Individual rats’ data are represented with white or grey circles. c) Rat-by-rat PCA scores, ranked from most negative to most positive. Control rats=black bars, ACRS rats=grey bars, ACRS rats defined as intermediates (PCA<0.3 and >−0.3)=white bars). d) CS+ lever (solid black, grey lines) and during cue food cup entries (dashed black, grey lines) emitted during the first, second, or third 25-cue blocks on sign/goal tracking extinction training test. * p<0.05, Main effect of ACRS on food cup entries.

Chamber Med Associates Rat Conditioned Place Preference Box, supplied by Med Associates Inc, used in various techniques. Bioz Stars score: 95/100, based on 282 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rat+cpp+boxes/CPP+Chamber/pmc05790819-94-32-33
Average 95 stars, based on 282 article reviews

chamber med associates rat conditioned place preference box - by Bioz Stars, 2026-11

95/100 stars

Images

1) Product Images from "Adolescent Cannabinoid Exposure Effects on Natural Reward Seeking and Learning in Rats"

Article Title: Adolescent Cannabinoid Exposure Effects on Natural Reward Seeking and Learning in Rats

Journal: Psychopharmacology

doi: 10.1007/s00213-017-4749-8

a) Pavlovian Conditioned Approach (PCA) score across training days. Black line=control, grey line=ACRS. Positive values indicate bias toward the CS+ lever (sign tracking), negative values indicated bias toward food cup (goal tracking) *p<0.05, group × day interaction. b) Mean+SEM PCA Score on training days 7&8 show with black (control) or grey (ACRS) horizontal lines and error bars. Individual rats’ data are represented with white or grey circles. c) Rat-by-rat PCA scores, ranked from most negative to most positive. Control rats=black bars, ACRS rats=grey bars, ACRS rats defined as intermediates (PCA<0.3 and >−0.3)=white bars). d) CS+ lever (solid black, grey lines) and during cue food cup entries (dashed black, grey lines) emitted during the first, second, or third 25-cue blocks on sign/goal tracking extinction training test. * p<0.05, Main effect of ACRS on food cup entries.

Figure Legend Snippet: a) Pavlovian Conditioned Approach (PCA) score across training days. Black line=control, grey line=ACRS. Positive values indicate bias toward the CS+ lever (sign tracking), negative values indicated bias toward food cup (goal tracking) *p<0.05, group × day interaction. b) Mean+SEM PCA Score on training days 7&8 show with black (control) or grey (ACRS) horizontal lines and error bars. Individual rats’ data are represented with white or grey circles. c) Rat-by-rat PCA scores, ranked from most negative to most positive. Control rats=black bars, ACRS rats=grey bars, ACRS rats defined as intermediates (PCA<0.3 and >−0.3)=white bars). d) CS+ lever (solid black, grey lines) and during cue food cup entries (dashed black, grey lines) emitted during the first, second, or third 25-cue blocks on sign/goal tracking extinction training test. * p<0.05, Main effect of ACRS on food cup entries.

Techniques Used: Control, Positive Control

other:

Article Title: Identification of small molecule ligands for GPR83 that modulate morphine antinociception and reward.
Article Snippet: The opioid crisis showcases a need for novel therapeutic avenues to treat drug abuse.. GPR83, a recently deorphanized G protein-coupled receptor shown to blunt morphine reward learning and regulate pain, is activated by the neuropeptide PEN and peptides derived from cholecystokinin.. To identify small molecule ligands, we generated a homology model based on the crystal structure of related receptors and used virtual screening on a library of 7 million compounds.

Article Title: Essential Roles of Heparan Sulfate Endosulfatase Sulf1 in Reward and Aversion Learning Through Distinct Dopamine D1 and D2 Receptor Pathways in Male Mice
Article Snippet: A three‐compartment apparatus (ENV‐3013; MED Associates, Fairfax, VT, USA), composed of a white chamber with a white mesh floor, a black chamber with a black grid rod floor, and a gray center compartment connecting the two chambers, was used.

Article Title: Astrocytic CREB regulates transcriptomic, neuronal, and behavioral responses to cocaine
Article Snippet: Astrocyte-specific CREB viruses were generated by Virovek by cloning CREB with the GfaABC1D promoter into an AAV2/5 with either a GFP or a tdTomato fluorescent tag.

Conditioned Place Preference:

Article Title: Adolescent mice exhibit lower reward sensitivity than adults.
Article Snippet: .. Cocaine conditioned place preference The cocaine CPP test was conducted using an automatic three-chamber apparatus (Med Associates, St. Albans, VT, USA, MED-CPP-MSAT) as described previously (Sora et al., 1998; Harda et al., 2020, 2025b). ..

Article Title: Acetazolamide inhibition of carbonic anhydrase 4 reverses opioid-induced synaptic rearrangements in nucleus accumbens and reduces drug-seeking behavior.
Article Snippet: .. In brief, mice underwent pre- and post-tests when they were allowed to explore a two-chamber CPP apparatus (Med Associates) for 20-min. For 3 days between pre- and posttests, mice underwent two training sessions daily, during which oxycodone (15mg/kg, i.p.) and saline were paired with opposite compartments. ..

Article Title: ZFP612 controls neuropathic pain through epigenetic repression of Il1rl1 within the silencer–promoter loop in primary sensory neurons of male mice
Article Snippet: .. The conditioned place preference (CPP) chambers consisted of two equal-sized compartments with distinct tactile and visual cues, connected by an internal door (MED Associates Inc.). ..

Article Title: Projection-defined ventral tegmental area neurons exhibit distinct fentanyl-induced molecular and functional adaptations that differentially support drug-context associations
Article Snippet: Fentanyl citrate (#22659) obtained from Cayman chemical (Ann Arbor, MI), and deschloroclozapine (#7193) obtained from Tocris Bioscience (Minneapolis, MN), were dissolved in sterile saline (0.9%). .. Conditioned place preference (CPP) was performed as previously described [ ] in a three-chambered rectangular apparatus consisting of a neutral center compartment and two side compartments with different contextual cues, connected by automatic guillotine doors, and equipped with infrared photobeam detectors that track animal position and movement (ENV-3013, MED Associates). ..

Saline:

Expressing:

Article Title: Dopamine and serotonin inversely modulate D2 medium spiny neurons to regulate cocaine reward.
Article Snippet: Briefly, GRAB sensors were excited by 465 nm and 560 nm frequency-modulated light and fluorescence signals were collected through low-autofluorescence patch cords, filtered through a fluorescence minicube, (Doric FMC6_IE(400-410)_E1(460-490)_F1(500-540)_E2(555570)_F2(590-680)), measured with dedicated photodetectors for each channel (Newport, 2151), sampled at 1.1073 Khz, and demodulated with an Rz5P signal processor running Synapse software (Tucker-Davis Technologies)17. .. After 6-8 weeks of expression, mice were allowed to explore a 2-sided CPP chamber with distinct tactile floors and wall patterns (Med Associates Inc.) in a 15 min pretest. ..

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