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nikon phase contrast microscope  (Nikon)


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    Structured Review

    Nikon nikon phase contrast microscope
    Nikon Phase Contrast Microscope, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 59970 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/phase+contrast+microscope/Objectives/pm41955441-67-5-5
    Average 99 stars, based on 59970 article reviews
    nikon phase contrast microscope - by Bioz Stars, 2026-10
    99/100 stars

    Images

    Related Articles

    Live Cell Imaging:

    Article Title: Proteomic and functional profiling of suspended jejunal enteroids reveals pharmacokinetic fidelity to native intestine
    Article Snippet: The enteroids were imaged using a Zeiss LSM800 confocal microscope equipped with a 20x objective and a 40x immersion oil objective. .. Live-cell imaging was performed on a custom-built microscope based on an Eclipse Ti2 body (Nikon), using a 10x/0.45 Plan Apo Lambda air objective (Nikon), and a back-lit sCMOS camera with a physical pixel size of 11 μm (Prime 95B, Photometrics), and a final image pixel size of 1.12 μm. ..

    Microscopy:

    Article Title: Proteomic and functional profiling of suspended jejunal enteroids reveals pharmacokinetic fidelity to native intestine
    Article Snippet: The enteroids were imaged using a Zeiss LSM800 confocal microscope equipped with a 20x objective and a 40x immersion oil objective. .. Live-cell imaging was performed on a custom-built microscope based on an Eclipse Ti2 body (Nikon), using a 10x/0.45 Plan Apo Lambda air objective (Nikon), and a back-lit sCMOS camera with a physical pixel size of 11 μm (Prime 95B, Photometrics), and a final image pixel size of 1.12 μm. ..

    Article Title: Comparative analysis of select 3D human mesenchymal stromal cell-derived spheroid models for adipogenic differentiation
    Article Snippet: .. Brightfield images were acquired using Epi-Fluorescence Eclipse TE300 microscope, equipped with a 10x objective (Nikon, Tokyo, Japan), and analysed with ImageJ Fiji software (National Institutes of Health, USA) to quantify spheroid size and morphology. ..

    Article Title: A method for expressing two proteins at a tunable ratio allows for studying the kinetics of creatine transport by MCT12
    Article Snippet: .. Two weeks later, single cell clones were identified by visual inspection with a 4 x /0.10 objective using a Nikon ECLIPSE Ts2 microscope (Nikon, Tokyo, Japan) and expanded. ..

    Article Title: A Nitric Oxide–Based STING Agonist Nanoadjuvant With ICD‐Derived Membrane Antigens Unleashes Robust Antitumor Immunity
    Article Snippet: .. Imaging was performed on a Nikon A1R HD25 confocal microscope using a 60× oil objective. ..

    Article Title: Sex‐Specific Effects of Dexmedetomidine on Brain Microvascular Endothelial Cell Function After Traumatic Brain Injury in Juvenile Mice
    Article Snippet: Cells were then incubated with BioTracker 633 Red Mitochondria Dye (100 nM; MilliporeSigma, MA, USA) and BioTracker Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator (100 nM; MilliporeSigma, MA, USA) for 30 min before imaging. .. Images were acquired using a Nikon Plan Apo 20×/0.9 objective mounted on a Nikon Eclipse TS2R fluorescence microscope (Nikon, NY, USA). ..

    Brightfield:

    Article Title: Comparative analysis of select 3D human mesenchymal stromal cell-derived spheroid models for adipogenic differentiation
    Article Snippet: .. Brightfield images were acquired using Epi-Fluorescence Eclipse TE300 microscope, equipped with a 10x objective (Nikon, Tokyo, Japan), and analysed with ImageJ Fiji software (National Institutes of Health, USA) to quantify spheroid size and morphology. ..

    Article Title: Gasdermin D-mediated delivery of caspase inhibitors to suppress pyroptosis.
    Article Snippet: Caspase-1, -4, -5 and -11 activate gasdermin D (GSDMD) pores, causing pyroptotic cell death and the release of the interleukins IL-1β and IL-18 (ref. 1).. Blocking this pathway holds therapeutic promise for the treatment of inflammatory disorders, but cellpermeable caspase inhibitors have not proved successful in clinical trials.. Here we describe covalent caspase inhibitors that selectively block pyroptosis and IL-1β secretion despite being excluded from healthy cells.

    Software:

    Article Title: Comparative analysis of select 3D human mesenchymal stromal cell-derived spheroid models for adipogenic differentiation
    Article Snippet: .. Brightfield images were acquired using Epi-Fluorescence Eclipse TE300 microscope, equipped with a 10x objective (Nikon, Tokyo, Japan), and analysed with ImageJ Fiji software (National Institutes of Health, USA) to quantify spheroid size and morphology. ..

    Article Title: O‐GlcNAcylation Stimulation Modulates Na+/K+ ATPase and Improves Outcomes in Hemorrhagic Shock
    Article Snippet: .. Images were acquired using a Nikon Eclipse Ti2 inverted microscope equipped with a Nikon DS‐Qi2 digital camera using a 40× objective and were analyzed using Image J software (V1.53U version). ..

    Morphology:

    Article Title: Comparative analysis of select 3D human mesenchymal stromal cell-derived spheroid models for adipogenic differentiation
    Article Snippet: .. Brightfield images were acquired using Epi-Fluorescence Eclipse TE300 microscope, equipped with a 10x objective (Nikon, Tokyo, Japan), and analysed with ImageJ Fiji software (National Institutes of Health, USA) to quantify spheroid size and morphology. ..

    Single Cell:

    Article Title: A method for expressing two proteins at a tunable ratio allows for studying the kinetics of creatine transport by MCT12
    Article Snippet: .. Two weeks later, single cell clones were identified by visual inspection with a 4 x /0.10 objective using a Nikon ECLIPSE Ts2 microscope (Nikon, Tokyo, Japan) and expanded. ..

    Clone Assay:

    Article Title: A method for expressing two proteins at a tunable ratio allows for studying the kinetics of creatine transport by MCT12
    Article Snippet: .. Two weeks later, single cell clones were identified by visual inspection with a 4 x /0.10 objective using a Nikon ECLIPSE Ts2 microscope (Nikon, Tokyo, Japan) and expanded. ..

    Process/Product Development:

    Article Title: A method for expressing two proteins at a tunable ratio allows for studying the kinetics of creatine transport by MCT12
    Article Snippet: .. Two weeks later, single cell clones were identified by visual inspection with a 4 x /0.10 objective using a Nikon ECLIPSE Ts2 microscope (Nikon, Tokyo, Japan) and expanded. ..

    Fluorescence:

    Article Title: Gasdermin D-mediated delivery of caspase inhibitors to suppress pyroptosis.
    Article Snippet: Caspase-1, -4, -5 and -11 activate gasdermin D (GSDMD) pores, causing pyroptotic cell death and the release of the interleukins IL-1β and IL-18 (ref. 1).. Blocking this pathway holds therapeutic promise for the treatment of inflammatory disorders, but cellpermeable caspase inhibitors have not proved successful in clinical trials.. Here we describe covalent caspase inhibitors that selectively block pyroptosis and IL-1β secretion despite being excluded from healthy cells.

    Article Title: Sex‐Specific Effects of Dexmedetomidine on Brain Microvascular Endothelial Cell Function After Traumatic Brain Injury in Juvenile Mice
    Article Snippet: Cells were then incubated with BioTracker 633 Red Mitochondria Dye (100 nM; MilliporeSigma, MA, USA) and BioTracker Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator (100 nM; MilliporeSigma, MA, USA) for 30 min before imaging. .. Images were acquired using a Nikon Plan Apo 20×/0.9 objective mounted on a Nikon Eclipse TS2R fluorescence microscope (Nikon, NY, USA). ..

    Spinning Disk:

    Article Title: Gasdermin D-mediated delivery of caspase inhibitors to suppress pyroptosis.
    Article Snippet: Caspase-1, -4, -5 and -11 activate gasdermin D (GSDMD) pores, causing pyroptotic cell death and the release of the interleukins IL-1β and IL-18 (ref. 1).. Blocking this pathway holds therapeutic promise for the treatment of inflammatory disorders, but cellpermeable caspase inhibitors have not proved successful in clinical trials.. Here we describe covalent caspase inhibitors that selectively block pyroptosis and IL-1β secretion despite being excluded from healthy cells.

    Confocal:

    Article Title: Gasdermin D-mediated delivery of caspase inhibitors to suppress pyroptosis.
    Article Snippet: Caspase-1, -4, -5 and -11 activate gasdermin D (GSDMD) pores, causing pyroptotic cell death and the release of the interleukins IL-1β and IL-18 (ref. 1).. Blocking this pathway holds therapeutic promise for the treatment of inflammatory disorders, but cellpermeable caspase inhibitors have not proved successful in clinical trials.. Here we describe covalent caspase inhibitors that selectively block pyroptosis and IL-1β secretion despite being excluded from healthy cells.

    Article Title: A Nitric Oxide–Based STING Agonist Nanoadjuvant With ICD‐Derived Membrane Antigens Unleashes Robust Antitumor Immunity
    Article Snippet: .. Imaging was performed on a Nikon A1R HD25 confocal microscope using a 60× oil objective. ..

    Inverted Microscopy:

    Article Title: O‐GlcNAcylation Stimulation Modulates Na+/K+ ATPase and Improves Outcomes in Hemorrhagic Shock
    Article Snippet: .. Images were acquired using a Nikon Eclipse Ti2 inverted microscope equipped with a Nikon DS‐Qi2 digital camera using a 40× objective and were analyzed using Image J software (V1.53U version). ..

    Imaging:

    Article Title: A Nitric Oxide–Based STING Agonist Nanoadjuvant With ICD‐Derived Membrane Antigens Unleashes Robust Antitumor Immunity
    Article Snippet: .. Imaging was performed on a Nikon A1R HD25 confocal microscope using a 60× oil objective. ..

    Phase Contrast:

    Article Title: Polyphasic taxonomic description of Micromonospora aquaegermanicae sp. nov. and Plantactinospora tunisiensis sp. nov.
    Article Snippet: A colony of strain JZT32T was streaked onto Glucose-Yeast ExtractMalt Extract agar (GYM, DSMZ 65) and incubated at 28 °C for 14 days. .. The purity of the strain was checked using phase-contrast light microscopy without staining (Nikon Eclipse, 100x objective lens). ..

    Light Microscopy:

    Article Title: Polyphasic taxonomic description of Micromonospora aquaegermanicae sp. nov. and Plantactinospora tunisiensis sp. nov.
    Article Snippet: A colony of strain JZT32T was streaked onto Glucose-Yeast ExtractMalt Extract agar (GYM, DSMZ 65) and incubated at 28 °C for 14 days. .. The purity of the strain was checked using phase-contrast light microscopy without staining (Nikon Eclipse, 100x objective lens). ..

    Staining:

    Article Title: Polyphasic taxonomic description of Micromonospora aquaegermanicae sp. nov. and Plantactinospora tunisiensis sp. nov.
    Article Snippet: A colony of strain JZT32T was streaked onto Glucose-Yeast ExtractMalt Extract agar (GYM, DSMZ 65) and incubated at 28 °C for 14 days. .. The purity of the strain was checked using phase-contrast light microscopy without staining (Nikon Eclipse, 100x objective lens). ..



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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Image Search Results


    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain

    Journal: BMC Oral Health

    Article Title: Dose-dependent effects of Metformin on proliferation and odontogenic differentiation of dental pulp stem cells

    doi: 10.1186/s12903-026-08221-w

    Figure Lengend Snippet: Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain

    Article Snippet: Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14.

    Techniques: Staining, Cell Culture, Control, Microscopy, Software, Derivative Assay