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Purdue University Cytometry liquid state nmr data
Liquid State Nmr Data, supplied by Purdue University Cytometry, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Article Title: Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance.
Article Snippet: The authors would like to thank the Purdue University Center for Cancer Research, which supports the shared NMR and mass spectrometry facilities.

Proton NMR:

Article Title: Enantioselective Total Synthesis of (-)-Zampanolide, a Potent Microtubule-Stabilizing Agent
Article Snippet: .. Potent Microtubule-Stabilizing Agent Arun K. Ghosh* and Xu Cheng Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN 47907 akghosh@purdue.edu Contents 1 H-NMR and 13 C-NMR Spectra.............................................................S-2 to S-41 HPLC data.................................................................................S-42 to S-46 S-2 O E t O O H T B D P S O 9 S-3 O E t O O H T B D P S O 9 S-4 O E t O O T B D P S O P h 1 0 S-5 O E t O O T B D P S O P h 1 0 S-6 O T B D P S O P h T M S 1 1 S-7 O T B D P S O P h T M S 1 1 S-8 O O T B D P S 6 S-9 O O T B D P S 6 S-10 O O T B D P S 6 S-11 p p m (f1 ) 0 .0 1 .0 2 .0 3 .0 4 .0 5 .0 6 .0 7 .0 8 .0 -5 0 0 5 0 1 0 0 1 5 0 2 0 0 2 5 0 3 0 0 3 5 0 7.659 7.655 7.640 7.636 7.389 7.366 7.358 7.354 4.882 4.873 4.864 4.781 4.777 4.762 4.757 3.807 3.793 3.788 3.773 3.760 3.745 3.731 3.720 3.689 3.683 3.678 3.673 3.413 3.390 3.059 3.051 2.409 2.392 1.040 1.033 0.93 2.00 3.61 1.17 0.88 1.05 1.19 2.35 1.26 2.61 9.01 4.42 10.98 O O T B D P S P h O H P h S-12 O O T B D P S 1 3 S-13 O O T B D P S 1 3 S-14 O T E S O P M B1 2 S-15 O T E S O P M B1 2 S-16 O O H O P M B H O 1 5 S-17 O O H O P M B H O 1 5 S-18 S-19 S-20 O O1 7 S-21 O O1 7 S-22 O O E t O H 1 8 S-23 O O E t O H 1 8 S-24 O O E t O P M B S-25 O O E t O P M B S-26 O O H O P M B 5 S-27 O O H O P M B 5 S-28 O O H P M B O 1 9 S-29 O O H P M B O 1 9 S-30 O M e O P M B M e O O P M B O 2 0 S-31 O M e O P M B M e O O P M B O 2 0 S-32 O O H O O H O S-33 O O H O O H O S-34 O O H C O O O (-)-2 S-35 O O H C O O O (-)-2 S-36 N H 2 O2 1 S-37 N H 2 O2 1 S-38 O O O O O H NH O 1 S-39 O O O O O H NH O 1 S-40 p p m ( t1 ) 0 .0 1 .0 2 .0 3 .0 4 .0 5 .0 6 .0 7 .0 8 .0 05 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 5 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1.00 1.13 1.26 0.87 0.88 0.92 0.90 0.85 1.06 0.89 1.04 0.99 2.11 2.05 0.92 1.100.65 1.16 1.59 1.02 0.97 1.32 3.08 2.18 1.79 4.06 3.25 2.89 3.37 O O O O O H N H O 2 3 S-41 p p m (t1 ) 1 .0 2 .0 3 .0 4 .0 5 .0 6 .0 7 .0 8 .0 0 5 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 7.6817.658. ..

High Performance Liquid Chromatography:

Article Title: Enantioselective Total Synthesis of (-)-Zampanolide, a Potent Microtubule-Stabilizing Agent
Article Snippet: .. Potent Microtubule-Stabilizing Agent Arun K. Ghosh* and Xu Cheng Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN 47907 akghosh@purdue.edu Contents 1 H-NMR and 13 C-NMR Spectra.............................................................S-2 to S-41 HPLC data.................................................................................S-42 to S-46 S-2 O E t O O H T B D P S O 9 S-3 O E t O O H T B D P S O 9 S-4 O E t O O T B D P S O P h 1 0 S-5 O E t O O T B D P S O P h 1 0 S-6 O T B D P S O P h T M S 1 1 S-7 O T B D P S O P h T M S 1 1 S-8 O O T B D P S 6 S-9 O O T B D P S 6 S-10 O O T B D P S 6 S-11 p p m (f1 ) 0 .0 1 .0 2 .0 3 .0 4 .0 5 .0 6 .0 7 .0 8 .0 -5 0 0 5 0 1 0 0 1 5 0 2 0 0 2 5 0 3 0 0 3 5 0 7.659 7.655 7.640 7.636 7.389 7.366 7.358 7.354 4.882 4.873 4.864 4.781 4.777 4.762 4.757 3.807 3.793 3.788 3.773 3.760 3.745 3.731 3.720 3.689 3.683 3.678 3.673 3.413 3.390 3.059 3.051 2.409 2.392 1.040 1.033 0.93 2.00 3.61 1.17 0.88 1.05 1.19 2.35 1.26 2.61 9.01 4.42 10.98 O O T B D P S P h O H P h S-12 O O T B D P S 1 3 S-13 O O T B D P S 1 3 S-14 O T E S O P M B1 2 S-15 O T E S O P M B1 2 S-16 O O H O P M B H O 1 5 S-17 O O H O P M B H O 1 5 S-18 S-19 S-20 O O1 7 S-21 O O1 7 S-22 O O E t O H 1 8 S-23 O O E t O H 1 8 S-24 O O E t O P M B S-25 O O E t O P M B S-26 O O H O P M B 5 S-27 O O H O P M B 5 S-28 O O H P M B O 1 9 S-29 O O H P M B O 1 9 S-30 O M e O P M B M e O O P M B O 2 0 S-31 O M e O P M B M e O O P M B O 2 0 S-32 O O H O O H O S-33 O O H O O H O S-34 O O H C O O O (-)-2 S-35 O O H C O O O (-)-2 S-36 N H 2 O2 1 S-37 N H 2 O2 1 S-38 O O O O O H NH O 1 S-39 O O O O O H NH O 1 S-40 p p m ( t1 ) 0 .0 1 .0 2 .0 3 .0 4 .0 5 .0 6 .0 7 .0 8 .0 05 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 5 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1.00 1.13 1.26 0.87 0.88 0.92 0.90 0.85 1.06 0.89 1.04 0.99 2.11 2.05 0.92 1.100.65 1.16 1.59 1.02 0.97 1.32 3.08 2.18 1.79 4.06 3.25 2.89 3.37 O O O O O H N H O 2 3 S-41 p p m (t1 ) 1 .0 2 .0 3 .0 4 .0 5 .0 6 .0 7 .0 8 .0 0 5 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 7.6817.658. ..

Nuclear Magnetic Resonance:

Article Title: How Solvation Energetics Dampen the Hydrogen Evolution Reaction to Maximize Zinc Anode Stability
Article Snippet: The authors acknowledge Alexandra Clark who assisted/acquired the images of cycled electrodes for this paper on a Zeiss Xradia 510 Versa 3D X-ray Microscope that was supported by the EVPRP Major Multi-User Equipment Program 2017 at Purdue University. .. The authors acknowledge Dr. John Harwood for helping recording nuclear magnetic resonance spectra at the Purdue University interdepartmental NMR facility. ..

Article Title: Enhancing intratumoral spread of radioluminescent nanoparticles via collagenase functionalization for radiation-induced photodynamic cancer therapy.
Article Snippet: Radioluminescent nanoparticles enable radiotherapyor X-ray-triggered photodynamic therapy (RT-PDT, also referred to as X-PDT in the literature) using the 5-aminolevulinic acid (ALA) prodrug, thereby overcoming the limited tissue penetration of conventional PDT.. However, their therapeutic efficacy remains constrained by poor intratumoral nanoparticle distribution.. To address this challenge, we developed collagenase-functionalized calcium tungstate nanoparticles capable of enzymatically degrading the extracellular matrix (ECM) in solid tumors.

Article Title: Stereoselective Organocatalytic Fucosylation with Isothioureas.
Article Snippet: This letter describes a catalytic, α-selective glycosylation of fucosyl chloride donors mediated by a nucleophilic thiourea.. This reaction is highly selective in forming both α-fucosyl and α-2-deoxy-2-azido-fucosylated glycosides, including sterically encumbered linkages.. Both conformationally flexible and constrained donors participate, giving good to complete α selectivity without the need for directing groups or temperature control.

Article Title: Preformulation studies of levonorgestrel: A supplier variation analysis.
Article Snippet: .. The authors thank Prof. Eric J. Munson from Purdue University and Prof. Michael Pedersen from the Southern University of Denmark for their support with the interpretation of the solid-state and liquid-state NMR data. ..

Article Title:
Article Snippet: .. S1 Supporting Information A Facile Method to Transform trans-4-Carboxy-3,4-dihydro-3-phenyl-1(2H)- isoquinolones to Indeno[1,2-c]isoquinolines Xiangshu Xiao and Mark Cushman* Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN 47907, USA Title page S1 1H NMR of compound 4 S2 1H NMR of compound 11 S3 1H NMR of compound 12 S4 ORTEP drawing of compound 10 S5 Corresponding Author: Phone number: 765-494-1465; fax number: 765-494-6790, email: cushman@pharmacy.purdue.edu S2 S3 S4 S5 ORTEP drawing of 10. ..



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