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Genotypic Technology Pvt Ltd whole-genome gene-expression microarray
Uptake and transport of silver in C. <t>reinhardtii.</t> Intracellular concentrations of silver (A) on exposure to 100 and 200 nM, and (Inset) to 500-nM exposure. No intracellular silver was quantifiable in C. reinhardtii exposed to 10 nM silver and is therefore not shown in the graph. Heat map of Cu transporters (B) in C. reinhardtii exposed to silver for varying durations with each box representing a protein at the transcriptome and proteome level, green being down-regulated and red up-regulated. The SD is shown in the figures. Atx1, antioxidant 1, copper chaperone; Cox2A, subunit 2A of cytochrome oxidase; Ctr1 and -3, copper transporter 1 and 3; Fox1, Ferroxidase; Pcy1, Plastocyanin. For the molecular responses, algae exposed to 500 nM Ag+ were not analyzed (see Methods).
Whole Genome Gene Expression Microarray, supplied by Genotypic Technology Pvt Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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whole-genome gene-expression microarray - by Bioz Stars, 2026-11
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1) Product Images from "Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver"

Article Title: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver

Journal: Proceedings of the National Academy of Sciences of the United States of America

doi: 10.1073/pnas.1319388111

Uptake and transport of silver in C. reinhardtii. Intracellular concentrations of silver (A) on exposure to 100 and 200 nM, and (Inset) to 500-nM exposure. No intracellular silver was quantifiable in C. reinhardtii exposed to 10 nM silver and is therefore not shown in the graph. Heat map of Cu transporters (B) in C. reinhardtii exposed to silver for varying durations with each box representing a protein at the transcriptome and proteome level, green being down-regulated and red up-regulated. The SD is shown in the figures. Atx1, antioxidant 1, copper chaperone; Cox2A, subunit 2A of cytochrome oxidase; Ctr1 and -3, copper transporter 1 and 3; Fox1, Ferroxidase; Pcy1, Plastocyanin. For the molecular responses, algae exposed to 500 nM Ag+ were not analyzed (see Methods).
Figure Legend Snippet: Uptake and transport of silver in C. reinhardtii. Intracellular concentrations of silver (A) on exposure to 100 and 200 nM, and (Inset) to 500-nM exposure. No intracellular silver was quantifiable in C. reinhardtii exposed to 10 nM silver and is therefore not shown in the graph. Heat map of Cu transporters (B) in C. reinhardtii exposed to silver for varying durations with each box representing a protein at the transcriptome and proteome level, green being down-regulated and red up-regulated. The SD is shown in the figures. Atx1, antioxidant 1, copper chaperone; Cox2A, subunit 2A of cytochrome oxidase; Ctr1 and -3, copper transporter 1 and 3; Fox1, Ferroxidase; Pcy1, Plastocyanin. For the molecular responses, algae exposed to 500 nM Ag+ were not analyzed (see Methods).

Techniques Used: Algae

Regulation of functional pathways in C. reinhardtii at physiological (A, C, E, G) and molecular (B, D, F, H) levels. Photosynthesis (A, B); lipid peroxidation compared with the control (C) and oxidative stress response (D); growth (E, F); ATP content (G) and synthesis (H). In the heat maps each square represents a protein, with green being down-regulated and red up-regulated. For the molecular responses, algae exposed to 500 nM Ag+ were not analyzed (see Methods).
Figure Legend Snippet: Regulation of functional pathways in C. reinhardtii at physiological (A, C, E, G) and molecular (B, D, F, H) levels. Photosynthesis (A, B); lipid peroxidation compared with the control (C) and oxidative stress response (D); growth (E, F); ATP content (G) and synthesis (H). In the heat maps each square represents a protein, with green being down-regulated and red up-regulated. For the molecular responses, algae exposed to 500 nM Ag+ were not analyzed (see Methods).

Techniques Used: Functional Assay, Control, Algae

Molecular and physiological changes of lipid synthesis in C. reinhardtii exposed to silver for 1 h. Regulation of proteins (A) and lipid bodies containing precursors of lipids stained green with Nile red (B). The chloroplasts autoflourescence is seen as red. (Scale bars in B, 10 µm.) For the molecular responses, algae exposed to 500 nM Ag+ were not analyzed (see Methods).
Figure Legend Snippet: Molecular and physiological changes of lipid synthesis in C. reinhardtii exposed to silver for 1 h. Regulation of proteins (A) and lipid bodies containing precursors of lipids stained green with Nile red (B). The chloroplasts autoflourescence is seen as red. (Scale bars in B, 10 µm.) For the molecular responses, algae exposed to 500 nM Ag+ were not analyzed (see Methods).

Techniques Used: Staining, Algae

The toxicity and adaptive response pathways, as derived from linking transcriptome and proteome responses to physiological effects. (A) Schematic representation of biological pathways in C. reinhardtii affected by Ag+. (B) Schematic representation of the toxicity pathway. (C) Schematic representation of the adaptive-response pathway.
Figure Legend Snippet: The toxicity and adaptive response pathways, as derived from linking transcriptome and proteome responses to physiological effects. (A) Schematic representation of biological pathways in C. reinhardtii affected by Ag+. (B) Schematic representation of the toxicity pathway. (C) Schematic representation of the adaptive-response pathway.

Techniques Used: Derivative Assay

Related Articles

Microarray:

Article Title: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver
Article Snippet: A C. reinhardtii whole-genome gene-expression microarray (Genotypic Technology) was designed using the JGI V4 Chlamydomonas best-transcripts database.

Algae:

Article Title: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver
Article Snippet: A C. reinhardtii whole-genome gene-expression microarray (Genotypic Technology) was designed using the JGI V4 Chlamydomonas best-transcripts database.

Functional Assay:

Article Title: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver
Article Snippet: A C. reinhardtii whole-genome gene-expression microarray (Genotypic Technology) was designed using the JGI V4 Chlamydomonas best-transcripts database.

Control:

Article Title: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver
Article Snippet: A C. reinhardtii whole-genome gene-expression microarray (Genotypic Technology) was designed using the JGI V4 Chlamydomonas best-transcripts database.

Staining:

Article Title: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver
Article Snippet: A C. reinhardtii whole-genome gene-expression microarray (Genotypic Technology) was designed using the JGI V4 Chlamydomonas best-transcripts database.

Derivative Assay:

Article Title: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver
Article Snippet: A C. reinhardtii whole-genome gene-expression microarray (Genotypic Technology) was designed using the JGI V4 Chlamydomonas best-transcripts database.



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Image Search Results


Flowchart of the study design. Genomic and transcriptomic data were extracted from the GEO database ( GSE83448 ).

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Flowchart of the study design. Genomic and transcriptomic data were extracted from the GEO database ( GSE83448 ).

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques:

Differentially expressed S-palmitoylation-related genes in 39 CD intestinal biopsies and 14 healthy controls. (A) PCA for GSE83448 . (B) Volcano plot illustrating 3743 DEGs. (C) Venn diagram depicting the overlap between DEGs and S-palmitoylation-related genes. (D) Heatmap representing the 23 SP-DEGs in CD and healthy controls. (E) Boxplots comparing the 23 SP-DEGs in CD and healthy controls. Abbreviations: CD: Crohn’s disease; PCA: Principal component analysis; DEGs: Differentially expressed genes; SP-DEGs: S-palmitoylation-related differentially expressed genes.

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Differentially expressed S-palmitoylation-related genes in 39 CD intestinal biopsies and 14 healthy controls. (A) PCA for GSE83448 . (B) Volcano plot illustrating 3743 DEGs. (C) Venn diagram depicting the overlap between DEGs and S-palmitoylation-related genes. (D) Heatmap representing the 23 SP-DEGs in CD and healthy controls. (E) Boxplots comparing the 23 SP-DEGs in CD and healthy controls. Abbreviations: CD: Crohn’s disease; PCA: Principal component analysis; DEGs: Differentially expressed genes; SP-DEGs: S-palmitoylation-related differentially expressed genes.

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques:

Functional enrichment analysis of SP-DEGs in the GSE83448 dataset. (A) The bubble plot illustrates key enriched terms across various categories. BP denotes biological processes; CC indicates cellular components; and MF represents molecular functions. (B) The circle map emphasizes BPs associated with S-palmitoylation. (C) The bar plot presents the results of the functional enrichment analysis, ranked by statistical significance. (D) The Circos plot visualizes the functional associations across categories. Abbreviations: SP-DEGs: S-palmitoylation-related differentially expressed genes; BP: Biological process; CC: Cellular component; MF: Molecular function.

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Functional enrichment analysis of SP-DEGs in the GSE83448 dataset. (A) The bubble plot illustrates key enriched terms across various categories. BP denotes biological processes; CC indicates cellular components; and MF represents molecular functions. (B) The circle map emphasizes BPs associated with S-palmitoylation. (C) The bar plot presents the results of the functional enrichment analysis, ranked by statistical significance. (D) The Circos plot visualizes the functional associations across categories. Abbreviations: SP-DEGs: S-palmitoylation-related differentially expressed genes; BP: Biological process; CC: Cellular component; MF: Molecular function.

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques: Functional Assay

Journal: bioRxiv

Article Title: Integrative Multi-Omic Profiling of the Human Phosphatome Identifies DUSP15 as a Tumour-Selective Regulator of Immune-Metabolic Reprogramming in Chromophobe Renal Cell Carcinoma

doi: 10.1101/2025.11.15.688610

Figure Lengend Snippet:

Article Snippet: Gene Expression Omnibus (GEO) microarray datasets used for independent validation were obtained from the National Center for Biotechnology Information (NCBI) GEO repository ( https://www.ncbi.nlm.nih.gov/geo/ ) under accession numbers GSE2748, GSE11024, GSE11151, GSE12090, GSE16441, GSE17895, GSE19982, GSE36895, GSE46699, and GSE53757.

Techniques: Expressing, Microarray