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Biotechnology Information microarray gene expression datasets
Microarray Gene Expression Datasets, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Microarray:

Article Title: Possible involvement of tubular interleukin-34 in macrophage recruitment during colistin-induced nephrotoxicity in rats.
Article Snippet: .. Complete microarray data have been submitted and are readily retrievable from the public database National Center for Biotechnology Information Vol. ..

Article Title: Genetic underpinnings of type-2 diabetes (T2D) with colorectal cancer (CRC): In-silico discovery of common molecular signatures, pathogenetic processes and therapeutic candidates
Article Snippet: .. Two microarray gene expression datasets for each of T2D and CRC were downloaded from the Gene Expression Omnibus (GEO) repository of the National Center for Biotechnology Information (NCBI). ..

Article Title: Genetic underpinnings of type-2 diabetes (T2D) with colorectal cancer (CRC): In-silico discovery of common molecular signatures, pathogenetic processes and therapeutic candidates.
Article Snippet: .. Two microarray gene expression datasets for each of T2D and CRC were downloaded from the Gene Expression Omnibus (GEO) repository of the National Center for Biotechnology Information (NCBI). ..

Article Title: AI guided discovery of a murine model of asymptomatic Alzheimer’s disease
Article Snippet: .. Publicly available microarray and RNA-sequencing datasets were obtained from the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) repository [ – ]. .. For Affymetrix microarray platforms, raw intensity files were normalized using Robust Multichip Average (RMA) [ ].

Article Title: cIAP1 inhibitor of apoptosis is a tumor suppressor in Ewing sarcoma.
Article Snippet: Ewing sarcoma (EwS) is a highly aggressive pediatric malignancy driven by EWSR1::ETS fusion oncoproteins –primarily EWSR1::FLI1– which deregulate genes essential for differentiation, proliferation, and cell survival.. To uncover key downstream targets of this fusion involved in cell differentiation, we combined transcriptomic profiling of EwS cell lines following EWSR1::ETS inhibition with gene ontology analysis, a clinically annotated gene expression dataset derived from EwS patient material and network analyses.. This integrative approach identified inhibitor of apoptosis protein 1 (cIAP1, alias BIRC2) as an EWSR1::FLI1-suppressed gene.

Article Title: Zfand5 terminates TLR3/4 signaling and necroptosis by targeting TRIF to the proteasome for degradation.
Article Snippet: .. Given that PRR-driven innate immune response must be tightly regulated to ensure proper initiation and resolution of inflammation (42), we investigated how macrophages respond to the TLR4 agonist lipopolysaccharide (LPS) by analyzing publicly available microarray data from the National Center for Biotechnology Information (NCBI). ..

Article Title: Small proline-rich protein 1A is a novel target of peroxisome proliferator-activated receptor gamma in steatotic liver disease.
Article Snippet: Peroxisome proliferator-activated receptor gamma (PPARγ) is a central regulator of lipid homeostasis; however, the specific downstream effectors mediating hepatic steatosis remain incompletely defined.. In this study, we investigated the molecular basis, by which PPARγ regulates the expression of small proline-rich protein 1 A (SPRR1A) during the development of fatty liver.. We initially performed a bioinformatic re-analysis of publicly available microarray datasets to characterize the gene expression profiles associated with hepatic steatosis in leptin-deficient type 2 diabetic (ob/ob) mice and patients with metabolic dysfunction–associated steatotic liver disease (MASLD).

Article Title: Identification of susceptibility modules and genes through WGCNA and ceRNA network analysis in neuropathic pain-induced anxiodepression.
Article Snippet: .. The microarray data under access number GSE92718 were downloaded from the National Center of Biotechnology Information (NCBI) Gene Expression Omnibus (GEO; www.ncbi.nlm.nih.gov/). ..

Gene Expression:

Article Title: Genetic underpinnings of type-2 diabetes (T2D) with colorectal cancer (CRC): In-silico discovery of common molecular signatures, pathogenetic processes and therapeutic candidates
Article Snippet: .. Two microarray gene expression datasets for each of T2D and CRC were downloaded from the Gene Expression Omnibus (GEO) repository of the National Center for Biotechnology Information (NCBI). ..

Article Title: Genetic underpinnings of type-2 diabetes (T2D) with colorectal cancer (CRC): In-silico discovery of common molecular signatures, pathogenetic processes and therapeutic candidates.
Article Snippet: .. Two microarray gene expression datasets for each of T2D and CRC were downloaded from the Gene Expression Omnibus (GEO) repository of the National Center for Biotechnology Information (NCBI). ..

Article Title: AI guided discovery of a murine model of asymptomatic Alzheimer’s disease
Article Snippet: .. Publicly available microarray and RNA-sequencing datasets were obtained from the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) repository [ – ]. .. For Affymetrix microarray platforms, raw intensity files were normalized using Robust Multichip Average (RMA) [ ].

Article Title: Identification of susceptibility modules and genes through WGCNA and ceRNA network analysis in neuropathic pain-induced anxiodepression.
Article Snippet: .. The microarray data under access number GSE92718 were downloaded from the National Center of Biotechnology Information (NCBI) Gene Expression Omnibus (GEO; www.ncbi.nlm.nih.gov/). ..

RNA sequencing:

Article Title: AI guided discovery of a murine model of asymptomatic Alzheimer’s disease
Article Snippet: .. Publicly available microarray and RNA-sequencing datasets were obtained from the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) repository [ – ]. .. For Affymetrix microarray platforms, raw intensity files were normalized using Robust Multichip Average (RMA) [ ].



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Flowchart of the study design. Genomic and transcriptomic data were extracted from the GEO database ( <t>GSE83448</t> ).
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Flowchart of the study design. Genomic and transcriptomic data were extracted from the GEO database ( GSE83448 ).

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Flowchart of the study design. Genomic and transcriptomic data were extracted from the GEO database ( GSE83448 ).

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques:

Differentially expressed S-palmitoylation-related genes in 39 CD intestinal biopsies and 14 healthy controls. (A) PCA for GSE83448 . (B) Volcano plot illustrating 3743 DEGs. (C) Venn diagram depicting the overlap between DEGs and S-palmitoylation-related genes. (D) Heatmap representing the 23 SP-DEGs in CD and healthy controls. (E) Boxplots comparing the 23 SP-DEGs in CD and healthy controls. Abbreviations: CD: Crohn’s disease; PCA: Principal component analysis; DEGs: Differentially expressed genes; SP-DEGs: S-palmitoylation-related differentially expressed genes.

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Differentially expressed S-palmitoylation-related genes in 39 CD intestinal biopsies and 14 healthy controls. (A) PCA for GSE83448 . (B) Volcano plot illustrating 3743 DEGs. (C) Venn diagram depicting the overlap between DEGs and S-palmitoylation-related genes. (D) Heatmap representing the 23 SP-DEGs in CD and healthy controls. (E) Boxplots comparing the 23 SP-DEGs in CD and healthy controls. Abbreviations: CD: Crohn’s disease; PCA: Principal component analysis; DEGs: Differentially expressed genes; SP-DEGs: S-palmitoylation-related differentially expressed genes.

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques:

Functional enrichment analysis of SP-DEGs in the GSE83448 dataset. (A) The bubble plot illustrates key enriched terms across various categories. BP denotes biological processes; CC indicates cellular components; and MF represents molecular functions. (B) The circle map emphasizes BPs associated with S-palmitoylation. (C) The bar plot presents the results of the functional enrichment analysis, ranked by statistical significance. (D) The Circos plot visualizes the functional associations across categories. Abbreviations: SP-DEGs: S-palmitoylation-related differentially expressed genes; BP: Biological process; CC: Cellular component; MF: Molecular function.

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Functional enrichment analysis of SP-DEGs in the GSE83448 dataset. (A) The bubble plot illustrates key enriched terms across various categories. BP denotes biological processes; CC indicates cellular components; and MF represents molecular functions. (B) The circle map emphasizes BPs associated with S-palmitoylation. (C) The bar plot presents the results of the functional enrichment analysis, ranked by statistical significance. (D) The Circos plot visualizes the functional associations across categories. Abbreviations: SP-DEGs: S-palmitoylation-related differentially expressed genes; BP: Biological process; CC: Cellular component; MF: Molecular function.

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques: Functional Assay

Journal: bioRxiv

Article Title: Integrative Multi-Omic Profiling of the Human Phosphatome Identifies DUSP15 as a Tumour-Selective Regulator of Immune-Metabolic Reprogramming in Chromophobe Renal Cell Carcinoma

doi: 10.1101/2025.11.15.688610

Figure Lengend Snippet:

Article Snippet: Gene Expression Omnibus (GEO) microarray datasets used for independent validation were obtained from the National Center for Biotechnology Information (NCBI) GEO repository ( https://www.ncbi.nlm.nih.gov/geo/ ) under accession numbers GSE2748, GSE11024, GSE11151, GSE12090, GSE16441, GSE17895, GSE19982, GSE36895, GSE46699, and GSE53757.

Techniques: Expressing, Microarray