recombinant mouse leptin (R&D Systems)

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R&D Systems recombinant mouse leptin
Recombinant Mouse Leptin, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 200 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leptin/Recombinant+Mouse+Leptin+Protein%2C+CF/pm42017526-76-0-3
Average 95 stars, based on 200 article reviews

recombinant mouse leptin - by Bioz Stars, 2026-09

95/100 stars

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Recombinant:

Article Title: Leptin Reduces Running in a Rodent Anorexia Nervosa Model via a Distributed Neural Network.
Article Snippet: .. Recombinant mouse leptin (R&D Systems, USA) was stored at −20°C and freshly prepared before use by dissolving in phosphate‐buffered saline (PBS; 137 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.3) at 1 μg/μL concentration. ..

Article Title: TonEBP as a key regulator of hypothalamic leptin signaling and resistance.
Article Snippet: .. AR TIC LE IN PR ES S ARTICLE IN PRESS Following a one-week recovery period in individual cages, mice fasted for 24 h were administered recombinant mouse leptin (1 or 3 μg/2 μl/mouse; R&D Systems, Minneapolis, MN) or saline (vehicle control) via Intracerebroventricular (i.c.v.) injection. ..

Article Title: A uniquely leptin sensitive hypothalamic neuron population limits hyperphagia and weight gain in diet-induced obesity
Article Snippet: .. Mouse recombinant leptin (R&D Systems, #498-OB) was reconstituted to 1 mg/ml in 20 mM Tris-HCl pH 8.0 (Invitrogen, #10434742). ..

Article Title: Phenethyl isothiocyanate ameliorates high-fat diet-induced obesity by antagonizing hypothalamic leptin resistance
Article Snippet: This is a PDF of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability.. This version will undergo additional copyediting, typesetting and review before it is published in its final form.. As such, this version is no longer the Accepted Manuscript, but it is not yet the definitive Version of Record; we are providing this early version to give early visibility of the article.

Saline:

Article Title: Metabolic regulation by tanycyte-derived extracellular vesicles through insulin precursor-mediated neuronal recognition and mTORC component delivery.
Article Snippet: The hypothalamus regulates feeding and metabolic balance in response to metabolic cues.. Here we report that extracellular vesicles (EVs) are secreted from the mediobasal hypothalamus in a diurnal manner that is influenced by daily feeding.. Sox2-positive tanycytes have a critical role in maintaining the diurnal pattern of hypothalamic EV release.

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Sterility:

Article Title: A catecholamine-independent pathway controlling adaptive adipocyte lipolysis.
Article Snippet: .. In brief, osmotic pumps (Alzet, model 1002) were filled according to the manufacturer’s instructions with sterile PBS or leptin (R&D Systems, 498-OB) reconstituted with PBS. .. For ICV surgeries, brain infusion cannulas and catheter tubes (Alzet, Brain Infusion Kit 3) were also filled and connected to the pumps.

Article Title: A catecholamine-independent pathway controlling adaptive adipocyte lipolysis
Article Snippet: .. In brief, osmotic pumps (Alzet, model 1002) were filled according to the manufacturer’s instructions with sterile PBS or leptin (R&D Systems, 498-OB) reconstituted with PBS. .. For ICV surgeries, brain infusion cannulas and catheter tubes (Alzet, Brain Infusion Kit 3) were also filled and connected to the pumps.

Review