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Jackson Laboratory female mrl mpj fas lpr j mice
Female Mrl Mpj Fas Lpr J Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fa/lpr+mice+mrl/us12648945-607-0-12
Average 86 stars, based on 1 article reviews
female mrl mpj fas lpr j mice - by Bioz Stars, 2026-10
86/100 stars

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Article Title: Neutrophil-targeted liposomal inhibition of PAD4-mediated NETosis in systemic lupus erythematosus.
Article Snippet: Efficacy studies in MRL/MpJ-Faslpr/J mice Female MRL/MpJ-Faslpr/J mice from The Jackson Laboratory (Bar Harbor, ME), aged 7 weeks, were acclimatized for one week in the animal facility with free access to food and water.

Article Title: Compositions and methods for treating systemic lupus erythematosus
Article Snippet: Female MRL/MpJ-Fas lpr/J mice (18-20 g, 7-8 weeks old) were obtained from The Jackson Laboratory.

Article Title: Single‐Chain Anti‐IL‐1β Antibody Carried by Outer Membrane Vesicles of Bacteroides fragilis Alleviates Tubular Inflammation in Chronic Kidney Disease
Article Snippet: Specific pathogen‐free, 8‐week‐old female MRL/lpr and MRL/MpJ mice (The Jackson Laboratory) were used for the LN model.

Article Title: Animal Models of Lupus Nephritis: Current Status and Future Perspectives.
Article Snippet: Lupus nephritis (LN) represents one of the most severe complications associated with systemic lupus erythematosus (SLE) characterized by a complex pathogenesis.. Animal models play a pivotal role in elucidating the pathogenesis of LN, facilitating drug discovery, and evaluating therapeutic interventions.. A diverse array of LN animal models is currently employed in research.

Article Title: Ultra-precision deconvolution of spatial transcriptomics decodes immune heterogeneity and fate-defining programs in tissues.
Article Snippet: MRL/MpJ (MRL; RRID: IMSR_JAX:000486) and C57BL/6 (B6; RRID: MGI:2159769) mice of both sexes, aged 8-10 weeks, were used for ear wound creation.

Article Title: Single-Chain Anti-IL-1β Antibody Carried by Outer Membrane Vesicles of Bacteroides fragilis Alleviates Tubular Inflammation in Chronic Kidney Disease.
Article Snippet: See the T erm s and C onditions (https://onlinelibrary.w iley.com /term s-and-conditions) on W iley O nline L ibrary for rules of use; O A articles are governed by the applicable C reative 8-week-old female MRL/lpr and MRL/MpJ mice (The Jackson Laboratory) were used for the LN model.

Article Title: PPAR-α Agonist Suppresses Expression of Immune Mediators in B Cells in a Murine Model of Systemic Lupus Erythematosus.
Article Snippet: Female MRL/lpr mice and Balb/c mice (wild-type [WT]) were purchased from Jackson Laboratories (Bar Harbor, ME, USA); eight-week-old mice weighing 25–30 g were used.

Article Title: Neutrophil-targeted liposomal inhibition of PAD4-mediated NETosis in systemic lupus erythematosus.
Article Snippet: NET formation was visualized using Axio Observer Zeiss Z1 microscope (Zeiss, Oberkochen, Germany).



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The effect of fisetin (10 and 20 µM) on Jurkat cell survival, measured using XTT assay. In the presence and absence of Fas receptor inhibitor Met-12. Data represented as mean ± SEM ( n = 3) Statistical analysis carried out using ANOVA followed by Tukey’s post hoc test for significance (* p < 0.05) (*** p < 0.001) (**** p < 0.0001).

Journal: International Journal of Molecular Sciences

Article Title: Synergistic Induction of Caspase-8-Mediated Leukaemic Cell Death by Fisetin and Pinocembrin

doi: 10.3390/ijms27125622

Figure Lengend Snippet: The effect of fisetin (10 and 20 µM) on Jurkat cell survival, measured using XTT assay. In the presence and absence of Fas receptor inhibitor Met-12. Data represented as mean ± SEM ( n = 3) Statistical analysis carried out using ANOVA followed by Tukey’s post hoc test for significance (* p < 0.05) (*** p < 0.001) (**** p < 0.0001).

Article Snippet: Cells were treated with the Fas inhibitor Met-12 (CAS No. 1242964-46-0, purchased from MedChemExpress, catalogue number HY-P6440) at concentration of 20 μM and fisetin at concentrations of 10 μM and 20 μM, and combination treatments consisting of MET + fisetin (20 + 10 μM and 20 μM + 20 μM).

Techniques: XTT Assay