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The effect of fisetin (10 and 20 µM) on Jurkat cell survival, measured using XTT assay. In the presence and absence of Fas receptor inhibitor Met-12. Data represented as mean ± SEM ( n = 3) Statistical analysis carried out using ANOVA followed by Tukey’s post hoc test for significance (* p < 0.05) (*** p < 0.001) (**** p < 0.0001).

Journal: International Journal of Molecular Sciences

Article Title: Synergistic Induction of Caspase-8-Mediated Leukaemic Cell Death by Fisetin and Pinocembrin

doi: 10.3390/ijms27125622

Figure Lengend Snippet: The effect of fisetin (10 and 20 µM) on Jurkat cell survival, measured using XTT assay. In the presence and absence of Fas receptor inhibitor Met-12. Data represented as mean ± SEM ( n = 3) Statistical analysis carried out using ANOVA followed by Tukey’s post hoc test for significance (* p < 0.05) (*** p < 0.001) (**** p < 0.0001).

Article Snippet: Cells were treated with the Fas inhibitor Met-12 (CAS No. 1242964-46-0, purchased from MedChemExpress, catalogue number HY-P6440) at concentration of 20 μM and fisetin at concentrations of 10 μM and 20 μM, and combination treatments consisting of MET + fisetin (20 + 10 μM and 20 μM + 20 μM).

Techniques: XTT Assay