Review




Structured Review

GenMark Diagnostics esensor 2c19 test reagents
Esensor 2c19 Test Reagents, supplied by GenMark Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/esensor+2c19+test+reagents/esensor+2c19+test/pmc03310336-191-39-49
Average 90 stars, based on 1 article reviews
esensor 2c19 test reagents - by Bioz Stars, 2026-11
90/100 stars

Images

Related Articles

Variant Assay:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Article Title: Identification of CYP2C19 * 4B : pharmacogenetic implications for drug metabolism including clopidogrel responsiveness
Article Snippet: .. 3 Eleven variant CYP2C19 alleles (* 2 –* 10 , * 13 and * 17 ) were genotyped using the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA, USA) as per the manufacturer’s instructions. ..

Positive Control:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Sequencing:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Mutagenesis:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

Software:

Article Title: An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Article Snippet: For both cohorts, genomic DNA was isolated with the Puregene DNA Purification kit (Qiagen, Valencia, CA) according to the manufacturer’s instructions. .. 1⁄2F1 1⁄2T1 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 Genotyping The designations of all CYP2C19 alleles refer to those defined by the Cytochrome P450 Allele Nomenclature Committee (http://www.cypalleles.ki.se/cyp2c19.htm, last accessed September 5, 2013).7 Eleven variant CYP2C19 alleles (*2 to *10, *13, *17) were genotyped with the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) according to the manufacturer’s instructions and as previously described.12 The wild-type (*1) CYP2C19 allele was assigned in the absence of other detectable variant alleles, and representative positive control samples for the CYP2C19*17 and CYP2C19*4 alleles were confirmed by bidirectional sequencing with the use of Mutation Surveyor software version 4.0 (SoftGenetics, State College, PA). ..

other:

Article Title: Identification of CYP2C19 * 4B : pharmacogenetic implications for drug metabolism including clopidogrel responsiveness
Article Snippet: This research was supported in part by a research training grant (5 T32 GM082773) and a grant (UL1RR029887) for the Mount Sinai Institutes for Clinical and Translational Sciences from the National Center for Research Resources, National Institutes of Health. eSensor 2C19 Test reagents for this study were supplied by GenMark Diagnostics (Carlsbad, CA, USA).

Article Title: Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes
Article Snippet: Analyte-specific detection primer extension and subsequent hybridization of fluorescent-labeled primers to capture probes arrayed on the biofilm chip is automated using the INFINITI analyzer, which then scans the microarray, analyzes the data, and produces a report on the detection of single-nucleotide polymorphisms, copy number variants (deletions, duplications), insertions, and other types of variants.

Article Title: Exome Sequencing of Extreme Clopidogrel Response Phenotypes Identifies B4GALT2 as a Determinant of On-treatment Platelet Reactivity
Article Snippet: For the replication cohort (see below), 11 CYP2C19 alleles (* 2 - * 10 , * 13 , * 17 ) were genotyped using the eSensor® 2C19 Test (GenMark Diagnostics, Carlsbad, CA, USA) as per the manufacturer's instructions.

Article Title: Multi-ethnic Distribution of Clinically Relevant CYP2C Genotypes and Haplotypes
Article Snippet: Eleven variant CYP2C19 alleles (* 2 – * 10 , * , * 17 ) were genotyped using the eSensor 2C19 Test (GenMark Diagnostics, Carlsbad, CA) as per the manufacturer's instructions, and five additional variant CYP2C19 alleles (* 12 , * 14 – * , * 22 ) and ABCB1 c.3435C>T were genotyped using a custom multiplexed SNaPshot single base extension assay (Applied Biosystems, Carlsbad, CA) as previously described.



Similar Products

90
GenMark Diagnostics esensor 2c19 test reagents
Esensor 2c19 Test Reagents, supplied by GenMark Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/esensor+2c19+test+reagents/esensor+2c19+test/pmc03310336-191-39-49
Average 90 stars, based on 1 article reviews
esensor 2c19 test reagents - by Bioz Stars, 2026-11
90/100 stars
  Buy from Supplier

Image Search Results