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CapitalBio Corporation massarray platform
Massarray Platform, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dna+massarray/massarray+platform/pmc06062335-206-12-14
Average 90 stars, based on 1 article reviews
massarray platform - by Bioz Stars, 2026-09
90/100 stars

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Mass Spectrometry:

Article Title: CpG methylation of the GPX3 promoter in patients with Kashin-Beck Disease potentially promotes chondrocyte apoptosis.
Article Snippet: EZ-96 DNA methylation kit (Zymo Research, California, USA) was used to treat the genomic DNA (200 ng) of each participant with bisulfite according to the manufacturer’s instructions. .. The Agena MassARRAY platform (CapitalBio Corporation, Beijing, China) containing a matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometer and RNA base-specific cleavage (Mass CLEAVE), were both employed to quantify the methylation of GPX3 CpGs. .. Quantitative methylation data was obtained via a Spectro CHIP (Agena Bioscience, California, USA) and a Mass ARRAY Compact System (Agena Bioscience, California, USA).

Methylation:

Article Title: CpG methylation of the GPX3 promoter in patients with Kashin-Beck Disease potentially promotes chondrocyte apoptosis.
Article Snippet: EZ-96 DNA methylation kit (Zymo Research, California, USA) was used to treat the genomic DNA (200 ng) of each participant with bisulfite according to the manufacturer’s instructions. .. The Agena MassARRAY platform (CapitalBio Corporation, Beijing, China) containing a matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometer and RNA base-specific cleavage (Mass CLEAVE), were both employed to quantify the methylation of GPX3 CpGs. .. Quantitative methylation data was obtained via a Spectro CHIP (Agena Bioscience, California, USA) and a Mass ARRAY Compact System (Agena Bioscience, California, USA).

Article Title: Multigenerational genetic effects of paternal cadmium exposure on ovarian granulosa cell apoptosis.
Article Snippet: To explore whether paternal cadmium (Cd) exposure causes ovarian granulosa cell (GC) apoptosis in offspring and the multigenerational genetic effects.. From postnatal day 28 (PND28) until adulthood (PND56), SPF male Sprague–Dawley (SD) rats were gavaged daily with varying concentrations of CdCl2. (0, 0.5, 2, and 8 mg/kg).. After treatment, the F1 generation was produced by mating with untreated female rats, and the F1 generation male rats were mated with untreated female rats to produce the F2 generation.

Article Title: Hypomethylation of the ENPP3 promoter region contributes to the occurrence and development of ovarian endometriosis via the AKT/mTOR/4EBP1 signaling pathway.
Article Snippet: With a UV spectrophotometer (NanoDrop 2000; Thermo Fisher Scientific, Wilmington, DE), the concentration and purity of DNA were evaluated by the absorbance at 260 nm and 280 nm. .. Quantitative methylation analysis of the DNA fragments of ENPP3 gene was performed by using Agena MAssARRAY platform (CapitalBio, Beijing, China). .. A total of 1 μg of genomic DNA from each sample was converted with sodium bisulfite using the EZ DNA methylation kit (Zymo Research, Orange, CA, USA) and the modified DNA was amplified by PCR.

Article Title: Prenatal cadmium exposure has inter-generational adverse effects on Sertoli cells through the follicle-stimulating hormone receptor pathway
Article Snippet: .. The Sequenom MassARRAY platform (CapitalBio, Beijing, China) was used to perform the quantitative methylation analysis. ..

Article Title: Loss of SETD2-mediated downregulation of intracellular and exosomal miRNA-10b determines MAPK pathway activation and multidrug resistance in renal cancer.
Article Snippet: Department of Urology, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, China Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Department of Endocrinology, School of Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University, Hangzhou, China Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China

Article Title: DNA Hyper-methylation Associated With Schizophrenia May Lead to Increased Levels of Autoantibodies
Article Snippet: .. A Sequenom MassARRAY platform (CapitalBio) was used to perform the quantitative methylation analysis of candidate DMS. .. The PCR primers listed in were designed using Sequenom Epidesigner ( http://www.epidesigner.com ).

CpG Methylation Assay:

Article Title: Evaluating the link between DIO3-FA27 promoter methylation, biochemical indices, and heart failure progression.
Article Snippet: The genomic DNA was treated with bisulfite using EZ-96 DNA methylation kit (ZYMO Research, Irvine, CA) according to the manufacturer’s instructions and amplified by methylation-specific polymerase chain reaction (MSP). .. To measure the DIO3 CpG methylation, the Agena MassARRAY platform (CapitalBio Corporation, Beijing, China) was utilized. ..

other:

Article Title: CD2AP is a potential prognostic biomarker of renal clear cell carcinoma
Article Snippet: The Agena MassARRAY® platform (CapitalBio technology, Beijing) is used to detect methylation status of the promoter CpG site of CD2AP in multiple cells.



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Sequenom massarray quantitative dna methylation analysis
ZNF582-AS1 expression was regulated by <t>DNA</t> <t>methylation</t> in ccRCC. a Detection of CpG islands in ZNF582-AS1 promoter and design of MSP primers. The horizontal axis of the curved lines represents the input sequence of ZNF582-AS1, and the vertical axis of the curved lines represents GC percentage. TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom <t>MassARRAY</t> quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells. T refers to Tumor tissue of ccRCC, N refers to Adjacent normal kidney tissue. M = Methylated, U = Unmethylated
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ZNF582-AS1 expression was regulated by DNA methylation in ccRCC. a Detection of CpG islands in ZNF582-AS1 promoter and design of MSP primers. The horizontal axis of the curved lines represents the input sequence of ZNF582-AS1, and the vertical axis of the curved lines represents GC percentage. TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom MassARRAY quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells. T refers to Tumor tissue of ccRCC, N refers to Adjacent normal kidney tissue. M = Methylated, U = Unmethylated

Journal: Journal of Experimental & Clinical Cancer Research : CR

Article Title: Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1

doi: 10.1186/s13046-021-01889-8

Figure Lengend Snippet: ZNF582-AS1 expression was regulated by DNA methylation in ccRCC. a Detection of CpG islands in ZNF582-AS1 promoter and design of MSP primers. The horizontal axis of the curved lines represents the input sequence of ZNF582-AS1, and the vertical axis of the curved lines represents GC percentage. TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom MassARRAY quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells. T refers to Tumor tissue of ccRCC, N refers to Adjacent normal kidney tissue. M = Methylated, U = Unmethylated

Article Snippet: TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom MassARRAY quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells.

Techniques: Expressing, DNA Methylation Assay, Sequencing, Comparison, Methylation