digital arraytm ifc microfluidic device (fluidigm)

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fluidigm digital arraytm ifc microfluidic device
Digital Arraytm Ifc Microfluidic Device, supplied by fluidigm, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/digital+arraytm/access+array+microfluidic+system/us10501786-1273-0-14
Average 90 stars, based on 1 article reviews

digital arraytm ifc microfluidic device - by Bioz Stars, 2026-10

90/100 stars

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Clinical Proteomics:

Article Title: Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients.
Article Snippet: .. DNA extracted from tumor and preamplified plasma DNA were subjected to single-plex amplification on the Access Array microfluidic system (Fluidigm) using target-specific TP53 primers flanked by universal sequences CS1 and CS2 as described in the TAm-Seq protocol 11 . .. The harvested and diluted products were tagged off-chip by PCR with sample indexing primers that were also complementary to Illumina flow-cell sequences PE1 and PE2.

Amplification:

Article Title: Nucleic acid encoding reactions
Article Snippet: .. In particular embodiments, the inner or (inner and outer) amplification(s) is/are carried out in a microfluidic device designed to facilitate recovery of amplification products after the amplification reaction has been carried out, such as the ACCESS ARRAYTM IFC described herein (See FIGS. 2-9) and available from Fluidigm, Inc., South San Francisco, CA In illustrative devices of this type, dilation pumping can utilized to remove substantially all of the reaction products from the microfluidic device, providing uniformity between the various reaction product pools. ..

Article Title: Methylation profiling of 48 candidate genes in tumor and matched normal tissues from breast cancer patients.
Article Snippet: Gene-specific methylation alterations in breast cancer have been suggested to occur early in tumorigenesis and have the potential to be used for early detection and prevention.. The continuous increase in worldwide breast cancer incidences emphasizes the urgent need for identification of methylation biomarkers for early cancer detection and patient stratification.. Using microfluidic PCR-based target enrichment and next-generation bisulfite sequencing technology, we analyzed methylation status of 48 candidate genes in paired tumor and normal tissues from 180 Chinese breast cancer patients.

other:

Article Title: Microfluidics for genome-wide studies involving next generation sequencing
Article Snippet: Forshew et al . used a microfluidic system (Access Array, Fluidigm) to perform parallel single-plex amplification from multiple preamplified samples using multiple primer sets.

Polymerase Chain Reaction:

Article Title: Next Generation-Targeted Amplicon Sequencing (NG-TAS): an optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA
Article Snippet: .. The NG-TAS experimental workflow (Fig. a), starts with a multiplexed PCR step (7–8 primer pairs) performed using Access ArrayTM, a microfluidic system from Fluidigm. ..

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