Review



human ccl21 6ckine  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    R&D Systems human ccl21 6ckine
    Human Ccl21 6ckine, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 33 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/Recombinant+Human+CCL21%2F6Ckine+Protein%2C+CF/pmc04339430-189-16-20
    Average 94 stars, based on 33 article reviews
    human ccl21 6ckine - by Bioz Stars, 2026-11
    94/100 stars

    Images

    Related Articles

    Recombinant:

    Article Title: A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease.
    Article Snippet: Full length recombinant mouse CCL21 protein was purchased from R&D Systems. .. Full length recombinant human CCL21 protein was purchased from Novus Biologicals, Centennial, CO, USA. .. CCL21 (8–20 aa) and CCL21 (43–56 aa) peptides were synthesized by New England Peptide (Gardner, MA, USA).

    Article Title: CXCL12-stimulated lymphocytes produce secondary stimulants that affect the surrounding cell chemotaxis
    Article Snippet: .. Immediately after the addition of each CM, 1 μL of the cell suspension was loaded into each well of the microchamber, and 100 ng of recombinant human CCL21 (R & D Systems) was applied to the contra-wells. ..

    Suspension:

    Article Title: CXCL12-stimulated lymphocytes produce secondary stimulants that affect the surrounding cell chemotaxis
    Article Snippet: .. Immediately after the addition of each CM, 1 μL of the cell suspension was loaded into each well of the microchamber, and 100 ng of recombinant human CCL21 (R & D Systems) was applied to the contra-wells. ..



    Similar Products

    ccr7  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology ccr7
    Ccr7, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/10__3390_slash_biom16101499-75-34-35
    Average 98 stars, based on 1 article reviews
    ccr7 - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier
    ecl kit  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology ecl kit
    Ecl Kit, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/pm42874830-112-6-9
    Average 98 stars, based on 1 article reviews
    ecl kit - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier
    chemiluminescent substrate ecl  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology chemiluminescent substrate ecl
    Chemiluminescent Substrate Ecl, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/bio_rxiv__64898__2026__10__08__757814-138-15-18
    Average 98 stars, based on 1 article reviews
    chemiluminescent substrate ecl - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier
    ecl substrate  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology ecl substrate
    Ecl Substrate, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/pmc13563566-392-21-25
    Average 98 stars, based on 1 article reviews
    ecl substrate - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier
    ecl enhanced plus kit  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology ecl enhanced plus kit
    Ecl Enhanced Plus Kit, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/10__1016_slash_j__identj__2026__111182-68-1-6
    Average 98 stars, based on 1 article reviews
    ecl enhanced plus kit - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier
    ccl21  (R&D Systems)
    93
    R&D Systems ccl21
    Ccl21, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/Human+CCL21%2F6Ckine+DuoSet+ELISA/pm42775509-140-9-24
    Average 93 stars, based on 1 article reviews
    ccl21 - by Bioz Stars, 2026-11
    93/100 stars
    		  Buy from Supplier
    ecl super kit  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology ecl super kit
    Ecl Super Kit, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/pmc13587703-71-12-16
    Average 98 stars, based on 1 article reviews
    ecl super kit - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier
    pln540  (Addgene inc)
    94
    Addgene inc pln540
    A Experimental design. Primary human CD8⁺ T cells were co-engineered with a lentiviral construct encoding the NR4A2-responsive synthetic promoter SP73 driving mCherry and constitutive EGFP to identify transduced cells, together with a retroviral NY-ESO-1–specific TCR. Engineered T cells were expanded and co-cultured with NY-ESO-1–expressing SK-MEL23 melanoma cells. B Quantification of mCherry⁺ T cells over time during co-culture. SP73-engineered T cells show progressive reporter induction, whereas control cells transduced with the control promoter SP01 (lacking NR4A2 binding sites) remain at baseline levels. Data represent mean ± SEM of n = 3 independent donors. C Representative IncuCyte® live-cell images showing SP73-driven mCherry fluorescence during co-culture with SK-MEL23 melanoma cells; SP01 controls show negligible signal. D Expression of NR4A2 and activation/dysfunction-associated markers in engineered T cells during co-culture. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test. P values: CD39, P < 0.0001 for R0vsR2 and R0vsR4, P = 0.0048 for R2vsR4. NR4A2, P = 0.0375 for R0vsR2. LAG-3, P = 0.0194 for R0vsR2, P = 0.0097 for R0vsR4. TIM-3, P = 0.008 for R0vsR2, P = 0.0433 for R2vsR4. TIGIT, P = 0.0082 for R0vsR4, P = 0.0433 for R2vsR4. E Functional assessment of engineered T cells prior co-culture (R0) and following persistent antigen exposure (R4). Left: Quantification of IL-2⁺, TNFα⁺, CD107a⁺, and IFNγ⁺ cells following Leukocyte Activation Cocktail (LAC) stimulation. Right: Representative flow cytometry histograms illustrating shifts in cytokine-producing populations. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using a two-tailed paired t test comparing R0 vs R4. P values: IL-2, P = 0.0074; TNFα, P = 0.0068; CD107a, P = 0.0401; IFNγ, P = 0.0147. Source data for this figure is available in the file. Created in BioRender.
    Pln540, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/pLN540+(FuGW-G8p-IL12-P2A-CCL21-1Pe)+(Plasmid+%23105201)/pmc13677741-420-7-9
    Average 94 stars, based on 1 article reviews
    pln540 - by Bioz Stars, 2026-11
    94/100 stars
    		  Buy from Supplier
    ecl chemiluminescent substrate kit  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology ecl chemiluminescent substrate kit
    A Experimental design. Primary human CD8⁺ T cells were co-engineered with a lentiviral construct encoding the NR4A2-responsive synthetic promoter SP73 driving mCherry and constitutive EGFP to identify transduced cells, together with a retroviral NY-ESO-1–specific TCR. Engineered T cells were expanded and co-cultured with NY-ESO-1–expressing SK-MEL23 melanoma cells. B Quantification of mCherry⁺ T cells over time during co-culture. SP73-engineered T cells show progressive reporter induction, whereas control cells transduced with the control promoter SP01 (lacking NR4A2 binding sites) remain at baseline levels. Data represent mean ± SEM of n = 3 independent donors. C Representative IncuCyte® live-cell images showing SP73-driven mCherry fluorescence during co-culture with SK-MEL23 melanoma cells; SP01 controls show negligible signal. D Expression of NR4A2 and activation/dysfunction-associated markers in engineered T cells during co-culture. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test. P values: CD39, P < 0.0001 for R0vsR2 and R0vsR4, P = 0.0048 for R2vsR4. NR4A2, P = 0.0375 for R0vsR2. LAG-3, P = 0.0194 for R0vsR2, P = 0.0097 for R0vsR4. TIM-3, P = 0.008 for R0vsR2, P = 0.0433 for R2vsR4. TIGIT, P = 0.0082 for R0vsR4, P = 0.0433 for R2vsR4. E Functional assessment of engineered T cells prior co-culture (R0) and following persistent antigen exposure (R4). Left: Quantification of IL-2⁺, TNFα⁺, CD107a⁺, and IFNγ⁺ cells following Leukocyte Activation Cocktail (LAC) stimulation. Right: Representative flow cytometry histograms illustrating shifts in cytokine-producing populations. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using a two-tailed paired t test comparing R0 vs R4. P values: IL-2, P = 0.0074; TNFα, P = 0.0068; CD107a, P = 0.0401; IFNγ, P = 0.0147. Source data for this figure is available in the file. Created in BioRender.
    Ecl Chemiluminescent Substrate Kit, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/pmc13597843-61-5-9
    Average 98 stars, based on 1 article reviews
    ecl chemiluminescent substrate kit - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier
    ecl basic kit  (ABclonal Biotechnology)
    98
    ABclonal Biotechnology ecl basic kit
    A Experimental design. Primary human CD8⁺ T cells were co-engineered with a lentiviral construct encoding the NR4A2-responsive synthetic promoter SP73 driving mCherry and constitutive EGFP to identify transduced cells, together with a retroviral NY-ESO-1–specific TCR. Engineered T cells were expanded and co-cultured with NY-ESO-1–expressing SK-MEL23 melanoma cells. B Quantification of mCherry⁺ T cells over time during co-culture. SP73-engineered T cells show progressive reporter induction, whereas control cells transduced with the control promoter SP01 (lacking NR4A2 binding sites) remain at baseline levels. Data represent mean ± SEM of n = 3 independent donors. C Representative IncuCyte® live-cell images showing SP73-driven mCherry fluorescence during co-culture with SK-MEL23 melanoma cells; SP01 controls show negligible signal. D Expression of NR4A2 and activation/dysfunction-associated markers in engineered T cells during co-culture. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test. P values: CD39, P < 0.0001 for R0vsR2 and R0vsR4, P = 0.0048 for R2vsR4. NR4A2, P = 0.0375 for R0vsR2. LAG-3, P = 0.0194 for R0vsR2, P = 0.0097 for R0vsR4. TIM-3, P = 0.008 for R0vsR2, P = 0.0433 for R2vsR4. TIGIT, P = 0.0082 for R0vsR4, P = 0.0433 for R2vsR4. E Functional assessment of engineered T cells prior co-culture (R0) and following persistent antigen exposure (R4). Left: Quantification of IL-2⁺, TNFα⁺, CD107a⁺, and IFNγ⁺ cells following Leukocyte Activation Cocktail (LAC) stimulation. Right: Representative flow cytometry histograms illustrating shifts in cytokine-producing populations. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using a two-tailed paired t test comparing R0 vs R4. P values: IL-2, P = 0.0074; TNFα, P = 0.0068; CD107a, P = 0.0401; IFNγ, P = 0.0147. Source data for this figure is available in the file. Created in BioRender.
    Ecl Basic Kit, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccl21/CCL21+Rabbit+pAb/pm42687121-71-1-7
    Average 98 stars, based on 1 article reviews
    ecl basic kit - by Bioz Stars, 2026-11
    98/100 stars
    		  Buy from Supplier

    Image Search Results


    A Experimental design. Primary human CD8⁺ T cells were co-engineered with a lentiviral construct encoding the NR4A2-responsive synthetic promoter SP73 driving mCherry and constitutive EGFP to identify transduced cells, together with a retroviral NY-ESO-1–specific TCR. Engineered T cells were expanded and co-cultured with NY-ESO-1–expressing SK-MEL23 melanoma cells. B Quantification of mCherry⁺ T cells over time during co-culture. SP73-engineered T cells show progressive reporter induction, whereas control cells transduced with the control promoter SP01 (lacking NR4A2 binding sites) remain at baseline levels. Data represent mean ± SEM of n = 3 independent donors. C Representative IncuCyte® live-cell images showing SP73-driven mCherry fluorescence during co-culture with SK-MEL23 melanoma cells; SP01 controls show negligible signal. D Expression of NR4A2 and activation/dysfunction-associated markers in engineered T cells during co-culture. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test. P values: CD39, P < 0.0001 for R0vsR2 and R0vsR4, P = 0.0048 for R2vsR4. NR4A2, P = 0.0375 for R0vsR2. LAG-3, P = 0.0194 for R0vsR2, P = 0.0097 for R0vsR4. TIM-3, P = 0.008 for R0vsR2, P = 0.0433 for R2vsR4. TIGIT, P = 0.0082 for R0vsR4, P = 0.0433 for R2vsR4. E Functional assessment of engineered T cells prior co-culture (R0) and following persistent antigen exposure (R4). Left: Quantification of IL-2⁺, TNFα⁺, CD107a⁺, and IFNγ⁺ cells following Leukocyte Activation Cocktail (LAC) stimulation. Right: Representative flow cytometry histograms illustrating shifts in cytokine-producing populations. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using a two-tailed paired t test comparing R0 vs R4. P values: IL-2, P = 0.0074; TNFα, P = 0.0068; CD107a, P = 0.0401; IFNγ, P = 0.0147. Source data for this figure is available in the file. Created in BioRender.

    Journal: Nature Communications

    Article Title: A modular synthetic promoter toolkit for programmable gene control in activated and chronically stimulated T cells

    doi: 10.1038/s41467-026-77730-7

    Figure Lengend Snippet: A Experimental design. Primary human CD8⁺ T cells were co-engineered with a lentiviral construct encoding the NR4A2-responsive synthetic promoter SP73 driving mCherry and constitutive EGFP to identify transduced cells, together with a retroviral NY-ESO-1–specific TCR. Engineered T cells were expanded and co-cultured with NY-ESO-1–expressing SK-MEL23 melanoma cells. B Quantification of mCherry⁺ T cells over time during co-culture. SP73-engineered T cells show progressive reporter induction, whereas control cells transduced with the control promoter SP01 (lacking NR4A2 binding sites) remain at baseline levels. Data represent mean ± SEM of n = 3 independent donors. C Representative IncuCyte® live-cell images showing SP73-driven mCherry fluorescence during co-culture with SK-MEL23 melanoma cells; SP01 controls show negligible signal. D Expression of NR4A2 and activation/dysfunction-associated markers in engineered T cells during co-culture. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test. P values: CD39, P < 0.0001 for R0vsR2 and R0vsR4, P = 0.0048 for R2vsR4. NR4A2, P = 0.0375 for R0vsR2. LAG-3, P = 0.0194 for R0vsR2, P = 0.0097 for R0vsR4. TIM-3, P = 0.008 for R0vsR2, P = 0.0433 for R2vsR4. TIGIT, P = 0.0082 for R0vsR4, P = 0.0433 for R2vsR4. E Functional assessment of engineered T cells prior co-culture (R0) and following persistent antigen exposure (R4). Left: Quantification of IL-2⁺, TNFα⁺, CD107a⁺, and IFNγ⁺ cells following Leukocyte Activation Cocktail (LAC) stimulation. Right: Representative flow cytometry histograms illustrating shifts in cytokine-producing populations. Data represent mean ± SEM of n = 3 independent biological donors. Statistical analysis was performed using a two-tailed paired t test comparing R0 vs R4. P values: IL-2, P = 0.0074; TNFα, P = 0.0068; CD107a, P = 0.0401; IFNγ, P = 0.0147. Source data for this figure is available in the file. Created in BioRender.

    Article Snippet: The sequence of IL12p70 was obtained from pLN540 (FuGW-G8p-IL12-P2A-CCL21-1Pe) (Addgene #105201 ).

    Techniques: Construct, Retroviral, Cell Culture, Expressing, Co-culture Assay, Control, Transduction, Binding Assay, Fluorescence, Activation Assay, Analysis, Functional Assay, Flow Cytometry, Two Tailed Test