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Chrom Tech cbx1 chrom seq
Cbx1 Chrom Seq, supplied by Chrom Tech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cbx1/captured+cbx1+chrom+seq/pm41107828-227-2-3
Average 86 stars, based on 1 article reviews
cbx1 chrom seq - by Bioz Stars, 2026-10
86/100 stars

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Article Title: Targeting PURPL RNA enabled rejuvenation of senescence cells via epigenetic reprogramming.
Article Snippet: By intersecting CBX1 Chrom-seq-captured RNAs with lncRNA upregulated in senescent cells, we identified PURPL as the sole potential epigenetic regulator of senescence (Fig. 4B, Supplementary Table S6).

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Article Title: Targeting PURPL RNA enabled rejuvenation of senescence cells via epigenetic reprogramming
Article Snippet: Chrom-seq, previously developed in our laboratory, identifies RNAs that are significantly associated with epigenetically modified chromatin loci, such as histone H3 lysine 9 trimethylation (H3K9me3) or histone H3 lysine 4 trimethylation (H3K4me3), depending on the engineered chromatin reader (eCR) used [ ]. .. Given the established characteristic of heterochromatin loss during ageing [ ], we referred to RNAs associated with loci enriched in H3K9me3, an epigenetic marker of heterochromatin, obtained from Chrom-seq experiments using CBX1 eCR. .. By intersecting CBX1 Chrom-seq-captured RNAs with lncRNA upregulated in senescent cells, we identified PURPL as the sole potential epigenetic regulator of senescence (Fig. B, Supplementary Table ).



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