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Applied Precision Inc laser scanner arrayworx e standard biochip reader
Laser Scanner Arrayworx E Standard Biochip Reader, supplied by Applied Precision Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/arrayworx+e+scanner/modified+biochip+scanner+arrayworx/pmc03236191-218-7-14
Average 90 stars, based on 1 article reviews
laser scanner arrayworx e standard biochip reader - by Bioz Stars, 2026-10
90/100 stars

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Related Articles

Fluorescence:

Article Title: Cell-Based Dose Responses from Open-Well Microchambers
Article Snippet: Cell-based assays play a critical role in discovery of new drugs and facilitating research in cancer, immunology, and stem cells.. Conventionally, they are performed in Petri dishes, tubes, or well plates, using milliliters of reagents and thousands of cells to obtain one data point.. Here, we are introducing a new platform to realize cell-based assay capable of increased throughput and greater sensitivity with a limited number of cells.

Article Title: Charting microbial phenotypes in multiplex nanoliter batch bioreactors.
Article Snippet: High-throughput growth phenotyping is receiving great attention for establishing the genotype−phenotype map of sequenced organisms owing to the ready availability of complete genome sequences.. To date, microbial growth phenotypes have been investigated mostly by the conventional method of batch cultivation using test tubes, Erlenmeyer flasks, or the recently available microwell plates.. However, the current batch cultivation methods are timeand labor-intensive and often fail to consider sophisticated environmental changes.

Modification:

Article Title: Cell-Based Dose Responses from Open-Well Microchambers
Article Snippet: Cell-based assays play a critical role in discovery of new drugs and facilitating research in cancer, immunology, and stem cells.. Conventionally, they are performed in Petri dishes, tubes, or well plates, using milliliters of reagents and thousands of cells to obtain one data point.. Here, we are introducing a new platform to realize cell-based assay capable of increased throughput and greater sensitivity with a limited number of cells.

Article Title: Log-scale Dose Response of Inhibitors on a Chip
Article Snippet: .. Image acquisition and data processing We used a modified biochip scanner (arrayWoRx®, Applied Precision, WA) to acquire the images of the on-chip dose response reaction. ..

Article Title: Log-scale Dose Response of Inhibitors on a Chip
Article Snippet: .. We used a modified biochip scanner (arrayWoRx®, Applied Precision, WA) to acquire the images of the on-chip dose response reaction. ..

Article Title: Charting microbial phenotypes in multiplex nanoliter batch bioreactors.
Article Snippet: High-throughput growth phenotyping is receiving great attention for establishing the genotype−phenotype map of sequenced organisms owing to the ready availability of complete genome sequences.. To date, microbial growth phenotypes have been investigated mostly by the conventional method of batch cultivation using test tubes, Erlenmeyer flasks, or the recently available microwell plates.. However, the current batch cultivation methods are timeand labor-intensive and often fail to consider sophisticated environmental changes.

other:

Article Title: Transition from parenteral to enteral nutrition induces immediate diet-dependent gut histological and immunological responses in preterm neonates.
Article Snippet: Jayda Siggers, Per T. Sangild, Tim K. Jensen, Richard H. Siggers, Kerstin Skovgaard, Ann Cathrine F. Støy, Bent B. Jensen, Thomas Thymann, Stine B. Bering, and Mette Boye Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Frederiksberg; National Veterinary Institute, Technical University of Denmark, Denmark; and Department of Animal Health and Bioscience, Aarhus University, Tjele, Denmark

Article Title: Determination of antibiotic EC50 using a zero-flow microfluidic chip based growth phenotype assay.
Article Snippet: At present, the emergence of antibiotic resistant pathogenic bacteria has become a global concern in public health [1], thus there is a significant demand of generating new antibiotics to treat infections caused by resistant bacteria.. In antimicrobial drug discovery, assay systems, such as, phenotype[2] or target-based [3], are used to perform antimicrobial activity screening during hit-tolead process [4].. Through such process, an important value, EC50, can be obtained.

Cell Culture:

Article Title: Charting microbial phenotypes in multiplex nanoliter batch bioreactors.
Article Snippet: High-throughput growth phenotyping is receiving great attention for establishing the genotype−phenotype map of sequenced organisms owing to the ready availability of complete genome sequences.. To date, microbial growth phenotypes have been investigated mostly by the conventional method of batch cultivation using test tubes, Erlenmeyer flasks, or the recently available microwell plates.. However, the current batch cultivation methods are timeand labor-intensive and often fail to consider sophisticated environmental changes.



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a) microfluidic design: the device consists of two PDMS layers: flow (blue) and control (red). The chip is an array of eight rows by 48 columns for 384 unit cells. Each unit cell is composed of: two antibody chambers divided by a reaction chamber (1–2), 4 MITOMI buttons (3), a valve that segregates the unit cells (4), a valve that separates antibody and reaction chambers (5) and a valve for releasing pressure in the antibody chambers (6). b) The PDMS chip is aligned to an epoxy-functionalized slide onto which primary and secondary antibodies were spotted. c) Assay details: schematic of the unit cell and cross section of a button region: i) functionalization of the surface: BSA-biotin is flowed though the chip followed by neutravidin. Next, the buttons are closed and BSA-biotin flowed again to passivate all neutravidin molecules except for those located underneath the MITOMI buttons, ii) the biotinylated primary antibody is allowed to diffuse into the MITOMI detection chamber and is bound by neutravidin immobilizing it in the MITOMI detection regions, iii) the sample is flown through the device and antigens are captured by the surface immobilized antibodies, iv) finally, the fluorescently labeled secondary antibody is allowed to diffuse into the MITOMI area, binds to the antigen if present, and is trapped by MITOMI. The entire device is then quantitated using a DNA <t>microarray</t> scanner.
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a) microfluidic design: the device consists of two PDMS layers: flow (blue) and control (red). The chip is an array of eight rows by 48 columns for 384 unit cells. Each unit cell is composed of: two antibody chambers divided by a reaction chamber (1–2), 4 MITOMI buttons (3), a valve that segregates the unit cells (4), a valve that separates antibody and reaction chambers (5) and a valve for releasing pressure in the antibody chambers (6). b) The PDMS chip is aligned to an epoxy-functionalized slide onto which primary and secondary antibodies were spotted. c) Assay details: schematic of the unit cell and cross section of a button region: i) functionalization of the surface: BSA-biotin is flowed though the chip followed by neutravidin. Next, the buttons are closed and BSA-biotin flowed again to passivate all neutravidin molecules except for those located underneath the MITOMI buttons, ii) the biotinylated primary antibody is allowed to diffuse into the MITOMI detection chamber and is bound by neutravidin immobilizing it in the MITOMI detection regions, iii) the sample is flown through the device and antigens are captured by the surface immobilized antibodies, iv) finally, the fluorescently labeled secondary antibody is allowed to diffuse into the MITOMI area, binds to the antigen if present, and is trapped by MITOMI. The entire device is then quantitated using a DNA <t>microarray</t> scanner.
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Scanner Model Arrayworx E, supplied by Applied Precision Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


a) microfluidic design: the device consists of two PDMS layers: flow (blue) and control (red). The chip is an array of eight rows by 48 columns for 384 unit cells. Each unit cell is composed of: two antibody chambers divided by a reaction chamber (1–2), 4 MITOMI buttons (3), a valve that segregates the unit cells (4), a valve that separates antibody and reaction chambers (5) and a valve for releasing pressure in the antibody chambers (6). b) The PDMS chip is aligned to an epoxy-functionalized slide onto which primary and secondary antibodies were spotted. c) Assay details: schematic of the unit cell and cross section of a button region: i) functionalization of the surface: BSA-biotin is flowed though the chip followed by neutravidin. Next, the buttons are closed and BSA-biotin flowed again to passivate all neutravidin molecules except for those located underneath the MITOMI buttons, ii) the biotinylated primary antibody is allowed to diffuse into the MITOMI detection chamber and is bound by neutravidin immobilizing it in the MITOMI detection regions, iii) the sample is flown through the device and antigens are captured by the surface immobilized antibodies, iv) finally, the fluorescently labeled secondary antibody is allowed to diffuse into the MITOMI area, binds to the antigen if present, and is trapped by MITOMI. The entire device is then quantitated using a DNA microarray scanner.

Journal: PLoS ONE

Article Title: A Microfluidic Platform for High-Throughput Multiplexed Protein Quantitation

doi: 10.1371/journal.pone.0117744

Figure Lengend Snippet: a) microfluidic design: the device consists of two PDMS layers: flow (blue) and control (red). The chip is an array of eight rows by 48 columns for 384 unit cells. Each unit cell is composed of: two antibody chambers divided by a reaction chamber (1–2), 4 MITOMI buttons (3), a valve that segregates the unit cells (4), a valve that separates antibody and reaction chambers (5) and a valve for releasing pressure in the antibody chambers (6). b) The PDMS chip is aligned to an epoxy-functionalized slide onto which primary and secondary antibodies were spotted. c) Assay details: schematic of the unit cell and cross section of a button region: i) functionalization of the surface: BSA-biotin is flowed though the chip followed by neutravidin. Next, the buttons are closed and BSA-biotin flowed again to passivate all neutravidin molecules except for those located underneath the MITOMI buttons, ii) the biotinylated primary antibody is allowed to diffuse into the MITOMI detection chamber and is bound by neutravidin immobilizing it in the MITOMI detection regions, iii) the sample is flown through the device and antigens are captured by the surface immobilized antibodies, iv) finally, the fluorescently labeled secondary antibody is allowed to diffuse into the MITOMI area, binds to the antigen if present, and is trapped by MITOMI. The entire device is then quantitated using a DNA microarray scanner.

Article Snippet: The microfluidic device was scanned using a fluorescent microarray scanner (ArrayWorx e-Biochip Reader, Applied Precision, USA).

Techniques: Control, Labeling, Microarray