vx 702 (MedChemExpress)
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vx 702
Vx 702, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/vx+702/VX-702/bio_rxiv__64898__2026__03__12__711124-52-16-18
Average 94 stars, based on 5 article reviews
Vx 702, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/vx+702/VX-702/bio_rxiv__64898__2026__03__12__711124-52-16-18
Average 94 stars, based on 5 article reviews
vx 702 - by Bioz Stars,
2026-09
94/100 stars
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1) Product Images from "Rescuing functional defects in a zebrafish model of CDKL5 deficiency disorder: Contribution to the identification of new therapeutic compounds"
Article Title: Rescuing functional defects in a zebrafish model of CDKL5 deficiency disorder: Contribution to the identification of new therapeutic compounds
Journal: bioRxiv
doi: 10.64898/2026.03.12.711124
Figure Legend Snippet: A) Representative images of the WT, DMSO-treated cdkl5 ⁻/⁻ larvae and cdkl5 -/- larvae following drug treatment with fisetin, divalproex, resveratrol and VX-702, stained with Alcian blue. B) Schematic illustration of the analyzed craniofacial cartilage parameters, adapted from Raterman et al. C) Quantification of craniofacial cartilage parameters, including ceratohyal cartilage length (Ch-l), palatoquadrate length (Pq-l), and ceratohyal cartilage width (Ch-w). Data are presented as median with interquartile range (n=29). Statistical analysis was performed using one-way ANOVA followed by Tukey’s multiple comparisons test. Significant differences are indicated by distinct lowercase letters.
Techniques Used: Staining
Figure Legend Snippet: RT-qPCR analysis was performed on larvae treated with 10 µM of fisetin, divalproex, resveratrol or VX-702 for 48h. WT and cdkl5 -/- control groups were treated with 0.1% DMSO as vehicle. Relative gene expression levels are presented as mean±SD of three biological replicates, except for the resveratrol group, which included two biological replicates. Each replicate consisted of a pool of 15 larvae. Statistical analysis was performed using one-way ANOVA followed by Tukey’s multiple comparisons test. Statistically significant differences are indicated by distinct lowercase letters.
Techniques Used: Quantitative RT-PCR, Control, Gene Expression
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