u87mg cell lines (ATCC)
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U87mg Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 10584 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/u87mg+cells/U-87+MG/pm42190431-440-3-10
Average 99 stars, based on 10584 article reviews
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In Vitro:Article Title: Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof Article Snippet: .. Test Purpose The purpose of this test is to test the in vitro inhibition effect of the drug compound of formula (D) of the present invention on the proliferation of Inhibition:Article Title: Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof Article Snippet: .. Test Purpose The purpose of this test is to test the in vitro inhibition effect of the drug compound of formula (D) of the present invention on the proliferation of Cell Culture:Article Title: Cell type-dependent suppression of the RNA helicase DDX3Y levels by the close paralog DDX3X Article Snippet: Secondary antibodies include HRP-conjugated mouse anti-β-actin (Cell Signaling Technology 8H10D10, 1:5,000), HRP-linked horse anti-mouse IgG (Cell Signaling Technology 7076, 1:10,000) and HRP-linked goat anti-rabbit IgG (Cell Signaling Technology 7074, 1:10,000). .. Article Title: Organelle contact reorganization drives calcium-dependent autophagy under proteostatic stress. Article Snippet: Organelle contact reorganization drives calciumdependent autophagy under proteostatic stress Yu B Ko, Minjeong Ko, Marius Ueffing , Hye Jin Kang & Ho Jeong Kwon To cite this article: Yu B Ko, Minjeong Ko, Marius Ueffing , Hye Jin Kang & Ho Jeong Kwon (18 May 2026): Organelle contact reorganization drives calcium-dependent autophagy under proteostatic stress, Autophagy, DOI: 10.1080/15548627.2026.2677184 To link to this article: https://doi.org/10.1080/15548627.2026.2677184 Article Title: Bayesian active learning-aided structure-based virtual screening reveals novel inhibitors of mutant IDH1. Article Snippet: Mutations in Isocitrate dehydrogenase 1 (IDH1) create neoenzymatic activity that drives the oncometabolite 2-hydroxyglutarate, motivating selective small-molecule inhibitors.. Here, we present a dual-strategy pipeline that integrates Bayesian neural network (BNN)-aided structure-based virtual screening (SBVS) with an active-learning-guided generative design loop.. Beginning from ~ 3.1 million candidate structures, a BNN provides calibrated activity means and uncertainties that drive upper-confidence-bound acquisition, while a Transformer-based generative model proposes scaffold-diverse analogs optimized for predicted binding affinity, physicochemical constraints, and ADMET priors. Modification:Article Title: Bayesian active learning-aided structure-based virtual screening reveals novel inhibitors of mutant IDH1. Article Snippet: Mutations in Isocitrate dehydrogenase 1 (IDH1) create neoenzymatic activity that drives the oncometabolite 2-hydroxyglutarate, motivating selective small-molecule inhibitors.. Here, we present a dual-strategy pipeline that integrates Bayesian neural network (BNN)-aided structure-based virtual screening (SBVS) with an active-learning-guided generative design loop.. Beginning from ~ 3.1 million candidate structures, a BNN provides calibrated activity means and uncertainties that drive upper-confidence-bound acquisition, while a Transformer-based generative model proposes scaffold-diverse analogs optimized for predicted binding affinity, physicochemical constraints, and ADMET priors. |
