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u133 plus2 microarray  (Thermo Fisher)


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    Structured Review

    Thermo Fisher u133 plus2 microarray
    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
    U133 Plus2 Microarray, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/u133+plus2+microarray/pmc11760970-204-19-19
    Average 90 stars, based on 1 article reviews
    u133 plus2 microarray - by Bioz Stars, 2026-10
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    Images

    1) Product Images from "Fam170a deficiency causes male infertility by impairing histone-to-protamine exchange during mouse spermiogenesis"

    Article Title: Fam170a deficiency causes male infertility by impairing histone-to-protamine exchange during mouse spermiogenesis

    Journal: Nucleic Acids Research

    doi: 10.1093/nar/gkaf023

    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and GDS2697 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
    Figure Legend Snippet: Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and GDS2697 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.

    Techniques Used: Immunofluorescence, Staining, Quantitative RT-PCR, Control

    Related Articles

    Expressing:

    Article Title: Fam170a deficiency causes male infertility by impairing histone-to-protamine exchange during mouse spermiogenesis.
    Article Snippet: Illumina Sentrix Expression (HumanRef-8) microbead microarray detection of 10 human male sperm samples (GDS2695, four normal and six teratozoospermia samples) revealed that the Fam170a transcription levels were significantly lower in the teratozoospermia samples than in the normal controls after t -test analysis (Fig. 1 D, P < .01). .. Similarly, the data from the Illumina Sentrix Expression (HumanRef-8) microbead microarray (five normal and eight teratozoospermia samples, GDS2696) and Affymetrix U133 plus2 microarray (13 normal and 8 teratozoospermia samples, GDS2697) revealed significantly decreased Fam170a mRNA abundance in the teratozoospermia samples (Fig. 1 D; P < .05, P < .01). ..

    Article Title: Fam170a deficiency causes male infertility by impairing histone-to-protamine exchange during mouse spermiogenesis
    Article Snippet: Illumina Sentrix Expression (HumanRef-8) microbead microarray detection of 10 human male sperm samples (GDS2695, four normal and six teratozoospermia samples) revealed that the Fam170a transcription levels were significantly lower in the teratozoospermia samples than in the normal controls after t -test analysis (Fig. , P < .01). .. Similarly, the data from the Illumina Sentrix Expression (HumanRef-8) microbead microarray (five normal and eight teratozoospermia samples, GDS2696) and Affymetrix U133 plus2 microarray (13 normal and 8 teratozoospermia samples, GDS2697) revealed significantly decreased Fam170a mRNA abundance in the teratozoospermia samples (Fig. ; P < .05, P < .01). ..

    Microarray:

    Article Title: Fam170a deficiency causes male infertility by impairing histone-to-protamine exchange during mouse spermiogenesis.
    Article Snippet: Illumina Sentrix Expression (HumanRef-8) microbead microarray detection of 10 human male sperm samples (GDS2695, four normal and six teratozoospermia samples) revealed that the Fam170a transcription levels were significantly lower in the teratozoospermia samples than in the normal controls after t -test analysis (Fig. 1 D, P < .01). .. Similarly, the data from the Illumina Sentrix Expression (HumanRef-8) microbead microarray (five normal and eight teratozoospermia samples, GDS2696) and Affymetrix U133 plus2 microarray (13 normal and 8 teratozoospermia samples, GDS2697) revealed significantly decreased Fam170a mRNA abundance in the teratozoospermia samples (Fig. 1 D; P < .05, P < .01). ..

    Article Title: Fam170a deficiency causes male infertility by impairing histone-to-protamine exchange during mouse spermiogenesis
    Article Snippet: Illumina Sentrix Expression (HumanRef-8) microbead microarray detection of 10 human male sperm samples (GDS2695, four normal and six teratozoospermia samples) revealed that the Fam170a transcription levels were significantly lower in the teratozoospermia samples than in the normal controls after t -test analysis (Fig. , P < .01). .. Similarly, the data from the Illumina Sentrix Expression (HumanRef-8) microbead microarray (five normal and eight teratozoospermia samples, GDS2696) and Affymetrix U133 plus2 microarray (13 normal and 8 teratozoospermia samples, GDS2697) revealed significantly decreased Fam170a mRNA abundance in the teratozoospermia samples (Fig. ; P < .05, P < .01). ..

    Article Title: STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL and BCLXL following glucocorticoid treatment
    Article Snippet: .. Affymetrix U133 Plus2 microarray data for the 117 patients as previously published were normalized using the robust multi-array average, computed by the affy package. ..



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    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
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    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
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    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
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    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
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    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
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    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
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    Thermo Fisher u133 plus2 microarray data
    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and <t>GDS2697</t> ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.
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    Image Search Results


    Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and GDS2697 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.

    Journal: Nucleic Acids Research

    Article Title: Fam170a deficiency causes male infertility by impairing histone-to-protamine exchange during mouse spermiogenesis

    doi: 10.1093/nar/gkaf023

    Figure Lengend Snippet: Fam170a is located in the nucleus of spermatids at steps 9–13 and has a low level of mRNA in human sperm from individuals with teratozoospermia. ( A , B ) Immunofluorescence staining displayed the localization and distribution of Fam170a protein in mouse and human seminiferous tubules, respectively. Roman numerals indicate the spermatogenic stages of the tubules in WT testicular sections. S: spermatid. The specific stages of mouse tubules were determined according to published criteria [ , ]. ( C ) Schematic summary of Fam170a protein localization during spermiogenesis. ( D ) Three different microarrays captured Fam170a gene transcription levels in sperm samples from normal and teratozoospermia men. The original data source is marked at the top of the histogram. GDS2695 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2695±FAM170A ), GDS2696 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2696+FAM170A ), and GDS2697 ( https://www.ncbi.nlm.nih.gov/geoprofiles/?term=GDS2697+FAM170A ); ** P < .01, * P < .005. The data are displayed as mean ± SEM. A t -test was performed, and false discovery rate (FDR) P -values were shown. ( E ) The relative Fam170a mRNA abundance in sperm samples from normal ( n = 4) and teratozoospermia ( n = 3) men after qRT-PCR analysis. The control data are displayed as mean ± SEM.

    Article Snippet: Similarly, the data from the Illumina Sentrix Expression (HumanRef-8) microbead microarray (five normal and eight teratozoospermia samples, GDS2696) and Affymetrix U133 plus2 microarray (13 normal and 8 teratozoospermia samples, GDS2697) revealed significantly decreased Fam170a mRNA abundance in the teratozoospermia samples (Fig. ; P < .05, P < .01).

    Techniques: Immunofluorescence, Staining, Quantitative RT-PCR, Control