triptolide (Thermo Fisher)
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Thermo Fisher
triptolide
Triptolide, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/triptolide/Triptolide/pmc12988324-38-32-33
Average 94 stars, based on 1 article reviews
Triptolide, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/triptolide/Triptolide/pmc12988324-38-32-33
Average 94 stars, based on 1 article reviews
triptolide - by Bioz Stars,
2026-10
94/100 stars
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1) Product Images from "Multiplexed TrAEL-seq captures DNA replication dynamics in mammalian cells"
Article Title: Multiplexed TrAEL-seq captures DNA replication dynamics in mammalian cells
Journal: Nucleic Acids Research
doi: 10.1093/nar/gkag212
Figure Legend Snippet: Causes of replication fork processivity differences across the genome. ( A ) Metaplot of TrAEL-seq read count in DLD-1 cells averaged across genes ± 100 kb. Genes are stratified for transcriptional activity based on PRO-seq into 0%–40%, 40–70%, 70%–90%, and 90%–100% categories. Profiles were normalized individually to make background read counts as close as possible. ( B ) Plots of total TrAEL-seq read count at increasing distance from replication Initiation Zones, stratified for nascent transcription level by PRO-seq. Analysis was performed as in Fig. , but the genomic windows included were filtered to remove the top 25%, 50%, or 75% of regions based on PRO-seq read count. ( C ) Total TrAEL-seq read count at increasing distance from replication Initiation Zones in untreated DLD-1 cells or cells treated for 2 h with 100 µM DRB or for 4 h with 3 µM triptolide. ( D ) Metaplot of TrAEL-seq read count over genes ± 100 kb as in panel (A) in DLD-1 cells ± DRB and triptolide (datasets as in panel (C), data is an average of the two biological replicates shown). ( E ) Total TrAEL-seq read count at increasing distance from replication Initiation Zones in untreated DLD-1 cells and cells treated for with 1 µM Cerelasertib for 24 h. ( F ) Total TrAEL-seq read count at increasing distance from replication Initiation Zones in untreated PC9 cells and cells treated for 24 h with 16 nM palbociclib.
Techniques Used: Activity Assay
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