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tcr activator pd l1 cho cell  (BPS Bioscience)


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    Structured Review

    BPS Bioscience tcr activator pd l1 cho cell
    Tcr Activator Pd L1 Cho Cell, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 94/100, based on 36 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tcr+activator/PD-L1+%2F+TCR+Activator+-+CHO+Recombinant+Cell+Line/us12583839-1286-9-17
    Average 94 stars, based on 36 article reviews
    tcr activator pd l1 cho cell - by Bioz Stars, 2026-10
    94/100 stars

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    Related Articles

    Recombinant:

    Article Title: Chlorin e6-associated photodynamic therapy enhances abscopal antitumor effects via inhibition of PD-1/PD-L1 immune checkpoint
    Article Snippet: .. Recombinant Jurkat T cells constitutively expressing human PD-1 and NFAT reporter genes (#60,535, hPD-1/NFAT Jurkat T cells) and recombinant CHO-K1 cells expressing human PD-L1 and TCR activator were both procured from BPS Bioscience. .. The Jurkat T cells were cultured in RPMI-1640 medium (GE Healthcare Life Sciences, Chicago, IL, USA) supplemented with 10% FBS and antibiotics (100 U/mL penicillin and 100 mg/mL streptomycin).

    Article Title: Plasma Extracellular Vesicles Enhance HIV-1 Infection of Activated CD4 + T Cells and Promote the Activation of Latently Infected J-Lat10.6 Cells via miR-139-5p Transfer
    Article Snippet: .. Recombinant Jurkat T cells which constitutively express PD-1 (BPS Bioscience, CA, USA) and Chinese Hamster Ovary (CHO) cells which constitutively express PD-L1 and an engineered TCR activator were purchased from BPS Bioscience (CA, USA). ..

    Expressing:

    Article Title: Chlorin e6-associated photodynamic therapy enhances abscopal antitumor effects via inhibition of PD-1/PD-L1 immune checkpoint
    Article Snippet: .. Recombinant Jurkat T cells constitutively expressing human PD-1 and NFAT reporter genes (#60,535, hPD-1/NFAT Jurkat T cells) and recombinant CHO-K1 cells expressing human PD-L1 and TCR activator were both procured from BPS Bioscience. .. The Jurkat T cells were cultured in RPMI-1640 medium (GE Healthcare Life Sciences, Chicago, IL, USA) supplemented with 10% FBS and antibiotics (100 U/mL penicillin and 100 mg/mL streptomycin).

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: .. CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: IC50 values were calculated by fitting the concentration– response curves with a four parameter logistic regression model using Prism 6.0 software (GraphPad Software). .. Neutralization of PD-L1/PD-1 interaction by NFAT reporter gene assay CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Stable Transfection:

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: .. CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: IC50 values were calculated by fitting the concentration– response curves with a four parameter logistic regression model using Prism 6.0 software (GraphPad Software). .. Neutralization of PD-L1/PD-1 interaction by NFAT reporter gene assay CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Incubation:

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: .. CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: IC50 values were calculated by fitting the concentration– response curves with a four parameter logistic regression model using Prism 6.0 software (GraphPad Software). .. Neutralization of PD-L1/PD-1 interaction by NFAT reporter gene assay CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Activation Assay:

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: .. CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: IC50 values were calculated by fitting the concentration– response curves with a four parameter logistic regression model using Prism 6.0 software (GraphPad Software). .. Neutralization of PD-L1/PD-1 interaction by NFAT reporter gene assay CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Neutralization:

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: IC50 values were calculated by fitting the concentration– response curves with a four parameter logistic regression model using Prism 6.0 software (GraphPad Software). .. Neutralization of PD-L1/PD-1 interaction by NFAT reporter gene assay CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..

    Reporter Gene Assay:

    Article Title: Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade
    Article Snippet: IC50 values were calculated by fitting the concentration– response curves with a four parameter logistic regression model using Prism 6.0 software (GraphPad Software). .. Neutralization of PD-L1/PD-1 interaction by NFAT reporter gene assay CHO cells stably expressing PD-L1 and a TCR activator (BPS Bioscience, cat. 60536) were incubated with Jurkat T cells stably expressing PD-1 and a reporter gene to monitor T cell activation (BPS Bioscience, 60535). ..



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    Image Search Results


    A Body weight of hPD-1 knock-in mice during the treatment period. The mice were treated with vehicle or TER (10 or 30 mpk) for the indicated time. B Spleen weight of mice at the endpoint of the experiment. C Tumor volume was measured over time in hPD-1 knock-in mice bearing hPD-L1 MC38 tumors treated with vehicle or TER (10 or 30 mpk). Representative images of excised tumors from each group are shown. D Tumor weight at the endpoint of the experiment. E Flow cytometry analysis of CD8 + T-cell populations in tumors from each treatment group. F PD-L1 expression in tumors from each group, as assessed by western blot analysis. GAPDH was used as a loading control. G IHC staining of tumor sections for immune-related markers, including CD8 + T cells and GrB. Representative images from each group are shown, and the quantitation of marker-positive cells per field is presented. * <0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001 compared with the respective control.

    Journal: Oncogenesis

    Article Title: Teriflunomide modulates the PD-1/PD-L1 axis and enhances antitumor immunity in colorectal cancer

    doi: 10.1038/s41389-026-00607-3

    Figure Lengend Snippet: A Body weight of hPD-1 knock-in mice during the treatment period. The mice were treated with vehicle or TER (10 or 30 mpk) for the indicated time. B Spleen weight of mice at the endpoint of the experiment. C Tumor volume was measured over time in hPD-1 knock-in mice bearing hPD-L1 MC38 tumors treated with vehicle or TER (10 or 30 mpk). Representative images of excised tumors from each group are shown. D Tumor weight at the endpoint of the experiment. E Flow cytometry analysis of CD8 + T-cell populations in tumors from each treatment group. F PD-L1 expression in tumors from each group, as assessed by western blot analysis. GAPDH was used as a loading control. G IHC staining of tumor sections for immune-related markers, including CD8 + T cells and GrB. Representative images from each group are shown, and the quantitation of marker-positive cells per field is presented. * <0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001 compared with the respective control.

    Article Snippet: Recombinant Jurkat-T cells expressing human PD-1 and an NFAT reporter gene (hPD-1/NFAT Jurkat-T cells, #60535) and recombinant CHO-K1 cells expressing human PD-L1 and a T-cell receptor (TCR) activator (hPD-L1/TCR CHO-K1 cells, #60536) were obtained from BPS Bioscience.

    Techniques: Knock-In, Flow Cytometry, Expressing, Western Blot, Control, Immunohistochemistry, Quantitation Assay, Marker

    A Body weight of hPD-1 knock-in mice during the treatment period. The mice were treated with vehicle or TER (30 mpk) and received either an isotype control or a CD8 depletion antibody. B Spleen weight of mice at the endpoint of the experiment. C Tumor volume was measured in hPD-1 knock-in mice bearing hPD-L1 MC38 tumors over time following treatment with vehicle or TER (30 mpk) with or without CD8 depletion. Representative images of excised tumors from each group are shown. D Tumor weight at the endpoint of the experiment. E Flow cytometry analysis confirming CD8 + T-cell depletion in tumors from each treatment group. The proportion of CD8 + cells among total live cells was quantified. F IHC staining of tumor sections for CD8 + T cells and GrB. Representative images from each treatment group are shown, and the quantitation of marker-positive cells per field is presented. * <0.05, ** p < 0.01, and **** p < 0.0001 compared with the respective control.

    Journal: Oncogenesis

    Article Title: Teriflunomide modulates the PD-1/PD-L1 axis and enhances antitumor immunity in colorectal cancer

    doi: 10.1038/s41389-026-00607-3

    Figure Lengend Snippet: A Body weight of hPD-1 knock-in mice during the treatment period. The mice were treated with vehicle or TER (30 mpk) and received either an isotype control or a CD8 depletion antibody. B Spleen weight of mice at the endpoint of the experiment. C Tumor volume was measured in hPD-1 knock-in mice bearing hPD-L1 MC38 tumors over time following treatment with vehicle or TER (30 mpk) with or without CD8 depletion. Representative images of excised tumors from each group are shown. D Tumor weight at the endpoint of the experiment. E Flow cytometry analysis confirming CD8 + T-cell depletion in tumors from each treatment group. The proportion of CD8 + cells among total live cells was quantified. F IHC staining of tumor sections for CD8 + T cells and GrB. Representative images from each treatment group are shown, and the quantitation of marker-positive cells per field is presented. * <0.05, ** p < 0.01, and **** p < 0.0001 compared with the respective control.

    Article Snippet: Recombinant Jurkat-T cells expressing human PD-1 and an NFAT reporter gene (hPD-1/NFAT Jurkat-T cells, #60535) and recombinant CHO-K1 cells expressing human PD-L1 and a T-cell receptor (TCR) activator (hPD-L1/TCR CHO-K1 cells, #60536) were obtained from BPS Bioscience.

    Techniques: Knock-In, Control, Flow Cytometry, Immunohistochemistry, Quantitation Assay, Marker