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ssm  (Element Science)

 
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    Element Science ssm
    Ssm, supplied by Element Science, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ssm/product/Element Science
    Average 86 stars, based on 1 article reviews
    ssm - by Bioz Stars, 2026-06
    86/100 stars

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    Furin inhibition reduces cIR-driven UII production, and UT and furin blockade attenuate cIR-induced cytotoxicity in primary neonatal pig proximal tubule epithelial cells. (A) Representative fluorescence microscopy images showing furin and UII immunostaining and their colocalization in primary neonatal pig proximal tubule epithelial cells (PTECs; 3 biological replicates). (B) Quantification of intracellular furin levels in control (ctrl) and chemical ischemia-reperfusion (cIR)–treated cells ( n = 4). (C) Secreted UII levels in cIR-treated cells in the absence or presence of the furin inhibitor <t>SSM3</t> <t>trifluoroacetate</t> (SSM3; n = 4). (D) cIR-induced cytotoxicity was significantly reduced by pharmacological inhibition of furin (SSM3) and by UT inhibition with urantide (URTD). * p < 0.05 ctrl vs. cIR; p < 0.05 cIR vs. SSM3 + cIR; $ p < 0.05 cIR vs. both SSM3 + cIR and URTD + cIR. Unpaired t -test (B); One-way ANOVA and Holm-Šídák’s multiple comparisons tests (C–D); n = 4, each. Scale bar = 50 µm.
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    A case of hemoptysis due to pulmonary carcinoma. (A) Preoperative computed tomography angiography showing the tumor-supplying arteries (arrowheads). (B) Prior coil embolization (arrowheads). (C) Acute angulation (<30°) between the thyrocervical trunk (thick arrowheads) and subclavian artery (thin arrowheads). (D) Steerable <t>microcatheter</t> tip angulation (arrowheads). (E) Postembolization angiography confirming the success of the procedure. Delayed angiography after embolization to confirm the absence of collateral regurgitation (arrowheads).
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    Image Search Results


    Furin inhibition reduces cIR-driven UII production, and UT and furin blockade attenuate cIR-induced cytotoxicity in primary neonatal pig proximal tubule epithelial cells. (A) Representative fluorescence microscopy images showing furin and UII immunostaining and their colocalization in primary neonatal pig proximal tubule epithelial cells (PTECs; 3 biological replicates). (B) Quantification of intracellular furin levels in control (ctrl) and chemical ischemia-reperfusion (cIR)–treated cells ( n = 4). (C) Secreted UII levels in cIR-treated cells in the absence or presence of the furin inhibitor SSM3 trifluoroacetate (SSM3; n = 4). (D) cIR-induced cytotoxicity was significantly reduced by pharmacological inhibition of furin (SSM3) and by UT inhibition with urantide (URTD). * p < 0.05 ctrl vs. cIR; p < 0.05 cIR vs. SSM3 + cIR; $ p < 0.05 cIR vs. both SSM3 + cIR and URTD + cIR. Unpaired t -test (B); One-way ANOVA and Holm-Šídák’s multiple comparisons tests (C–D); n = 4, each. Scale bar = 50 µm.

    Journal: Renal Failure

    Article Title: Urotensin II system contributes to ischemic acute kidney injury in neonatal pigs

    doi: 10.1080/0886022X.2025.2534018

    Figure Lengend Snippet: Furin inhibition reduces cIR-driven UII production, and UT and furin blockade attenuate cIR-induced cytotoxicity in primary neonatal pig proximal tubule epithelial cells. (A) Representative fluorescence microscopy images showing furin and UII immunostaining and their colocalization in primary neonatal pig proximal tubule epithelial cells (PTECs; 3 biological replicates). (B) Quantification of intracellular furin levels in control (ctrl) and chemical ischemia-reperfusion (cIR)–treated cells ( n = 4). (C) Secreted UII levels in cIR-treated cells in the absence or presence of the furin inhibitor SSM3 trifluoroacetate (SSM3; n = 4). (D) cIR-induced cytotoxicity was significantly reduced by pharmacological inhibition of furin (SSM3) and by UT inhibition with urantide (URTD). * p < 0.05 ctrl vs. cIR; p < 0.05 cIR vs. SSM3 + cIR; $ p < 0.05 cIR vs. both SSM3 + cIR and URTD + cIR. Unpaired t -test (B); One-way ANOVA and Holm-Šídák’s multiple comparisons tests (C–D); n = 4, each. Scale bar = 50 µm.

    Article Snippet: SSM3 trifluoroacetate was obtained from Tocris Bioscience (Bristol, UK), and urantide from Biosynth.

    Techniques: Inhibition, Fluorescence, Microscopy, Immunostaining, Control

    A case of hemoptysis due to pulmonary carcinoma. (A) Preoperative computed tomography angiography showing the tumor-supplying arteries (arrowheads). (B) Prior coil embolization (arrowheads). (C) Acute angulation (<30°) between the thyrocervical trunk (thick arrowheads) and subclavian artery (thin arrowheads). (D) Steerable microcatheter tip angulation (arrowheads). (E) Postembolization angiography confirming the success of the procedure. Delayed angiography after embolization to confirm the absence of collateral regurgitation (arrowheads).

    Journal: Journal of Thoracic Disease

    Article Title: Application of an advanced steerable microcatheter for challenging arterial embolization in massive hemoptysis

    doi: 10.21037/jtd-2025-815

    Figure Lengend Snippet: A case of hemoptysis due to pulmonary carcinoma. (A) Preoperative computed tomography angiography showing the tumor-supplying arteries (arrowheads). (B) Prior coil embolization (arrowheads). (C) Acute angulation (<30°) between the thyrocervical trunk (thick arrowheads) and subclavian artery (thin arrowheads). (D) Steerable microcatheter tip angulation (arrowheads). (E) Postembolization angiography confirming the success of the procedure. Delayed angiography after embolization to confirm the absence of collateral regurgitation (arrowheads).

    Article Snippet: • The SwiftNINJA ® steerable microcatheter (SSM) (Merit Medical) has been shown to be advantageous for the superselective embolization of complex vessels.

    Techniques: Computed Tomography

    The SSM (Merit Medical). (A) The SSM is a joint-style microcatheter with a near-end operation disc (thick arrowheads) and a far-end controllable tip (thin arrows) connected by two wires through the lumen of the catheter axis. (B) The SSM features an adjustable tip. (C) The proximal handle allows for single-handed operation. (D) The SSM features a tip with an adjustable angle of up to 180°. SSM, SwiftNINJA steerable microcatheter.

    Journal: Journal of Thoracic Disease

    Article Title: Application of an advanced steerable microcatheter for challenging arterial embolization in massive hemoptysis

    doi: 10.21037/jtd-2025-815

    Figure Lengend Snippet: The SSM (Merit Medical). (A) The SSM is a joint-style microcatheter with a near-end operation disc (thick arrowheads) and a far-end controllable tip (thin arrows) connected by two wires through the lumen of the catheter axis. (B) The SSM features an adjustable tip. (C) The proximal handle allows for single-handed operation. (D) The SSM features a tip with an adjustable angle of up to 180°. SSM, SwiftNINJA steerable microcatheter.

    Article Snippet: • The SwiftNINJA ® steerable microcatheter (SSM) (Merit Medical) has been shown to be advantageous for the superselective embolization of complex vessels.

    Techniques:

    A case of hemoptysis due to pulmonary carcinoma. (A) Preoperative computed tomography angiography showing the tumor-supplying arteries (arrowheads). (B) Prior coil embolization (arrowheads). (C) Acute angulation (<30°) between the thyrocervical trunk (thick arrowheads) and subclavian artery (thin arrowheads). (D) Steerable microcatheter tip angulation (arrowheads). (E) Postembolization angiography confirming the success of the procedure. Delayed angiography after embolization to confirm the absence of collateral regurgitation (arrowheads).

    Journal: Journal of Thoracic Disease

    Article Title: Application of an advanced steerable microcatheter for challenging arterial embolization in massive hemoptysis

    doi: 10.21037/jtd-2025-815

    Figure Lengend Snippet: A case of hemoptysis due to pulmonary carcinoma. (A) Preoperative computed tomography angiography showing the tumor-supplying arteries (arrowheads). (B) Prior coil embolization (arrowheads). (C) Acute angulation (<30°) between the thyrocervical trunk (thick arrowheads) and subclavian artery (thin arrowheads). (D) Steerable microcatheter tip angulation (arrowheads). (E) Postembolization angiography confirming the success of the procedure. Delayed angiography after embolization to confirm the absence of collateral regurgitation (arrowheads).

    Article Snippet: Subsequently, by using the SwiftNINJA ® steerable microcatheter (SSM) (Merit Medical, South Jordan, UT, USA), we accessed the responsible artery and successfully performed embolization.

    Techniques: Computed Tomography

    The SSM (Merit Medical). (A) The SSM is a joint-style microcatheter with a near-end operation disc (thick arrowheads) and a far-end controllable tip (thin arrows) connected by two wires through the lumen of the catheter axis. (B) The SSM features an adjustable tip. (C) The proximal handle allows for single-handed operation. (D) The SSM features a tip with an adjustable angle of up to 180°. SSM, SwiftNINJA steerable microcatheter.

    Journal: Journal of Thoracic Disease

    Article Title: Application of an advanced steerable microcatheter for challenging arterial embolization in massive hemoptysis

    doi: 10.21037/jtd-2025-815

    Figure Lengend Snippet: The SSM (Merit Medical). (A) The SSM is a joint-style microcatheter with a near-end operation disc (thick arrowheads) and a far-end controllable tip (thin arrows) connected by two wires through the lumen of the catheter axis. (B) The SSM features an adjustable tip. (C) The proximal handle allows for single-handed operation. (D) The SSM features a tip with an adjustable angle of up to 180°. SSM, SwiftNINJA steerable microcatheter.

    Article Snippet: Subsequently, by using the SwiftNINJA ® steerable microcatheter (SSM) (Merit Medical, South Jordan, UT, USA), we accessed the responsible artery and successfully performed embolization.

    Techniques:

    A case of hemoptysis due to pulmonary carcinoma. (A) Preoperative computed tomography angiography showing the tumor-supplying arteries (arrowheads). (B) Prior coil embolization (arrowheads). (C) Acute angulation (<30°) between the thyrocervical trunk (thick arrowheads) and subclavian artery (thin arrowheads). (D) Steerable microcatheter tip angulation (arrowheads). (E) Postembolization angiography confirming the success of the procedure. Delayed angiography after embolization to confirm the absence of collateral regurgitation (arrowheads).

    Journal: Journal of Thoracic Disease

    Article Title: Application of an advanced steerable microcatheter for challenging arterial embolization in massive hemoptysis

    doi: 10.21037/jtd-2025-815

    Figure Lengend Snippet: A case of hemoptysis due to pulmonary carcinoma. (A) Preoperative computed tomography angiography showing the tumor-supplying arteries (arrowheads). (B) Prior coil embolization (arrowheads). (C) Acute angulation (<30°) between the thyrocervical trunk (thick arrowheads) and subclavian artery (thin arrowheads). (D) Steerable microcatheter tip angulation (arrowheads). (E) Postembolization angiography confirming the success of the procedure. Delayed angiography after embolization to confirm the absence of collateral regurgitation (arrowheads).

    Article Snippet: The SwiftNINJA ® steerable microcatheter (SSM) (Merit Medical) optimizes the navigation of complex vessels through preset tip angles.

    Techniques: Computed Tomography

    The SSM (Merit Medical). (A) The SSM is a joint-style microcatheter with a near-end operation disc (thick arrowheads) and a far-end controllable tip (thin arrows) connected by two wires through the lumen of the catheter axis. (B) The SSM features an adjustable tip. (C) The proximal handle allows for single-handed operation. (D) The SSM features a tip with an adjustable angle of up to 180°. SSM, SwiftNINJA steerable microcatheter.

    Journal: Journal of Thoracic Disease

    Article Title: Application of an advanced steerable microcatheter for challenging arterial embolization in massive hemoptysis

    doi: 10.21037/jtd-2025-815

    Figure Lengend Snippet: The SSM (Merit Medical). (A) The SSM is a joint-style microcatheter with a near-end operation disc (thick arrowheads) and a far-end controllable tip (thin arrows) connected by two wires through the lumen of the catheter axis. (B) The SSM features an adjustable tip. (C) The proximal handle allows for single-handed operation. (D) The SSM features a tip with an adjustable angle of up to 180°. SSM, SwiftNINJA steerable microcatheter.

    Article Snippet: The SwiftNINJA ® steerable microcatheter (SSM) (Merit Medical) optimizes the navigation of complex vessels through preset tip angles.

    Techniques: